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A complex disease involves many etiological and risk factors operating at multiple levels molecular, cellular, organismal, and environmental. The incidence of such diseases as cancer, obesity, and diabetes are increasing in occurrence, urging us to think fundamentally and use a broader perspective to identify their connection and revolutionize treatments. The understanding of biological data derived from studying diseases can be enhanced by theories and mathematical models, which clarify the big picture and help to reveal the overarching mechanisms that govern complex biological phenomena....

The Chinese overseas now number 25 to 30 million, yet the 2,000-year history of Chinese attempts to venture abroad and the underlying values affecting that migration have never before been presented in a broad overview. Despite centuries of prohibition against leaving the land and traveling and settling overseas, the "earthbound" Chinese--first traders, then peasants and workers--eventually found new sources of livelihood abroad. The practice of sojourning, being always temporarily away from home, was the answer the Chinese overseas found to deal with imperial and orthodox concerns. Today...

With increasingly decentralized manufacturing systems and outsourcing, more robust and practical approaches and systems are needed to support agile manufacturing operations. Enterprise Networks and Logistics for Agile Manufacturing presents a focused collection of quality chapters on the state-of-the-art research efforts in the area of enterprise network and logistics, as well as their practical applications towards agile manufacturing. The book describes recent developments and innovations in this area, presenting both a broad-based review of the key areas of research in agile...

The reign of Emperor Jiaqing (1796-1820 CE) has long occupied an awkward position in studies of China's last dynasty, the Qing (1644-1911 CE). Conveniently marking a watershed between the prosperous eighteenth century and the tragic post-Opium War era, this quarter century has nevertheless been glossed over as an unremarkable interlude separating two well-studied epochs of great transformation. White Lotus Rebels and South China Pirates presents a major reassessment of this misunderstood period by examining how the emperors, bureaucrats, and foreigners responded to the two crises...