Chemistry of Opioids

ISBN-13: 9783642181061 / Angielski / Twarda / 2011 / 314 str.

Hiroshi Nagase

Opis

Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Traials; by K. Kawai and S. Sakami * Twin and Triplet Drugs in Opioid; by H. Fujii * Synthesis of Neoclerodane Diterpenes (Salvinorin Derivatives) and Their Pharmacological Effects; by T. E. Prisinzano * Synthesis of Novel Basic Opioid Skeletons Derived from Naltrexone; by H. Nagase * Nonpeptidic d Opioid Agonists: What Have We Learned?; by S. N. Calderson * Synthesis of 14-Alkoxy- and 14-Aminomorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea * Development of Novel Opioid Mimetics, Agonists and Antagonists; by Y. Okada and Y. Tsuda * 3D-Pharmacophore Identification for k Opioid Agonists Using Ligand-Based Drug Design Techniques; by N. Yamaotsu and S. Hironi.

Blurb

Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Trials; by H. Nagase and H. Fujii * Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea * 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions; by J. W. Lewis and S. M. Husbands * Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?; by S. N. Calderon * Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects; by K. M. Lovell, K. M. Prevatt-Smith, A. Lozama and T. E. Prisinzano * Synthesis of Novel Basic Skeletons Derived from Naltrexone; by H. Nagase and H. Fujii * Twin and Triplet Drugs in Opioid Research; by H. Fujii *  3D-Pharmacophore Identification for κ-Opioid Agonists Using Ligand-Based Drug-Design Techniques; by N. Yamaotsu and S. Hirono