Human Embryonic Stem Cells
ISBN: 9781588293114 / Angielski / Twarda / 461 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United...
A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from tr...
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585,00 zł |
Baculovirus and Insect Cell Expression Protocols
ISBN: 9781588295378 / Angielski / Twarda / 470 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Baculovirus Expression Protocols is a detailed guide for using the baculovirus expression vector system (BEVS) and/or insect cells to produce recombinant proteins. Procedures for the development and production of baculovirus insecticides at both laboratory and large scale are described in the kind of step-by-step format that the Methods in Molecular Biology series helped standardize. This book is a one-stop source for information on baculoviruses, and includes sections on using modified baculoviruses to express genes in mammalian cells, using Drosophila cell lines, isolating new cell... Baculovirus Expression Protocols is a detailed guide for using the baculovirus expression vector system (BEVS) and/or insect cells to produce recom... |
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585,00 zł |
PCR Primer Design
ISBN: 9781588297259 / Angielski / Twarda / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. At the heart of most high-throughput methods is the technique of polymerase chain reaction (PCR). This book focuses on primer design, which is critical to both the efficiency and the accuracy of the PCR. With intricate descriptions of basic approaches as well as specialized methods, "PCR Primer Design" is an exceptional reference for all those involved in studying the genome.
At the heart of most high-throughput methods is the technique of polymerase chain reaction (PCR). This book focuses on primer design, which is crit... |
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585,00 zł |
Gene Function Analysis
ISBN: 9781588297341 / Angielski / Twarda / 337 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume of Methods in Molecular Biology focuses on techniques to determine the function of a gene. Traditionally, the function of a gene was determined following cloning, which provided its DNA sequence and an ab- ity to modify this sequence. Experiments were performed that looked for p- notypic changes in a cell line or model organism following modifications to the sequence, knocking out of the gene, or enhancing expression of the gene. In the 1990 s, the growing sequence databases and the BLAST algorithm provided additional power by allowing identification of genes with known function...
This volume of Methods in Molecular Biology focuses on techniques to determine the function of a gene. Traditionally, the function of a gene was deter...
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585,00 zł |
Candida Albicans: Methods and Protocols
ISBN: 9781588297600 / Angielski / Twarda / 206 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place throughout a wide range of disciplines, and have come as the result of newly available genome sequences of pathogens such as candida albicans and other model fungi. In Candida Albicans: Methods and Protocols, expert researchers explore these exciting new insights, focusing on the study of medically important fungi and Candida spp in particular. Chapters examine critical aspects of molecular methods, providing information on reporter gene... Over the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place... |
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585,00 zł |
Plant Endocytosis
ISBN: 9783540281979 / Angielski / Twarda / 314 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Endocytosis is a fundamental biological process, which is conserved among all eukaryotes. It is essential not only for many physiological and signalling processes but also for interactions between eukaryotic cells and pathogens or symbionts. This book covers all aspects of endocytosis in both lower and higher plants, including basic types of endocytosis, endocytic compartments, and molecules involved in endocytic internalization and recycling in diverse plant cell types. It provides a comparison with endocytosis in animals and yeast and discusses future prospects in this new and rapidly... Endocytosis is a fundamental biological process, which is conserved among all eukaryotes. It is essential not only for many physiological and signa... |
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585,00 zł |
Signaling Pathways for Translation: Insulin and Nutrients
ISBN: 9783540417095 / Angielski / Twarda / 186 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The articles in the present volume are by major contributors to our under standing of signaling pathways affecting protein synthesis. They focus pri marily on two extracellular anabolic signals, although others are included as well. Insulin is one of the best-studied extracellular regulators of protein syn thesis. Several of the known pathways for regulation of protein synthesis were elucidated using insulin-dependent systems. Regulation of protein synthesis by amino acids, by contrast, is an emerging field that has recently received a great deal of attention. The dual role of amino acids as...
The articles in the present volume are by major contributors to our under standing of signaling pathways affecting protein synthesis. They focus pri m...
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585,00 zł |
Cell Immortalization
ISBN: 9783540656180 / Angielski / Twarda / 208 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The problem of the long-term proliferation of cells is a seminal one. It has always been a hot subject in biology, a source of far-reaching hypotheses, even more so now when explanations for the mechanisms of cell prolifera tive mortality or immortality seem within our reach. A question which is still debated is whether an infinite division potential can be a normal trait or is always the result of modifications leading to abnormal cell growth and escape from homeostasis. In general, investigators have been advocates of one of the two extremes, universal limited or unlim ited normal...
The problem of the long-term proliferation of cells is a seminal one. It has always been a hot subject in biology, a source of far-reaching hypotheses...
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585,00 zł |
Bioelectrochemistry of Membranes
ISBN: 9783764321666 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Bioelectrochemistry of Membranes is the last volume in the book series "Bioelectrochemistry: Principles and Practice" that provides a comprehensive compilation of physicochemical aspects of different biochemical and physiological processes. This sixth volume introduces basic knowledge and important electrochemical and biophysical aspects of membrane potentials, lipid bilayers and cell membranes. The volumes of this book series serve as source books for advanced students and researchers at all levels of bioelectrochemistry. Bioelectrochemistry of Membranes is the last volume in the book series "Bioelectrochemistry: Principles and Practice" that provide... |
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585,00 zł |
Biochemistry and Molecular Biology of Vitamin B6 and Pqq-Dependent Proteins
ISBN: 9783764361457 / Angielski / Twarda / 377 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The most recent information on proteins dependent upon Vitamin B6, PQQ or other quinones for function are included in this volume. It is a compilation of recent advances in the understanding of these proteins structures, mechanisms of action, and their biological roles and functions. In addition, the book contains sections devoted to the mechanisms of folding and to addressing the molecular physiology and pathology of these families of proteins, which are of intense biomedical interest. Emerging information regarding the participation of these proteins in enzymatic activity and their...
The most recent information on proteins dependent upon Vitamin B6, PQQ or other quinones for function are included in this volume. It is a compilation...
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585,00 zł |
Cox-2 Inhibitors
ISBN: 9783764369019 / Angielski / Twarda / 250 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.
COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this f...
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585,00 zł |
Heat Shock Proteins and Inflammation
ISBN: 9783764369323 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Heat shock proteins (HSP) have received ample interest by immunologists over recent years. Initially they were found to be dominantly immunogenic microbial antigens. The connection with inflammation was established when it was uncovered that T cells specific for these antigens have a crucial role in the induction and regulation of experimental arthritis. Since then, the raised presence of immunity to HSPs in virtually all conditions of inflammation, including autoimmune diseases, transplant rejection and atherosclerosis, has emphasised the critical significance of immunity to HSPs in...
Heat shock proteins (HSP) have received ample interest by immunologists over recent years. Initially they were found to be dominantly immunogenic micr...
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585,00 zł |
Skeletal Muscle Repair and Regeneration
ISBN: 9781402067679 / Angielski / Twarda / 379 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Skeletal muscle is the most abundant tissue of our body. Apart from its essential role in locomotion, it is also the body s main store of carbohydrate and protein as well as being one of the principal generators of heat. Its proper maintenance and function are, therefore, essential. A severe acute loss of muscle function is potentially lethal and the debilitating effects of chronic decline in mobility are commonplace experience, so repair and maintenance of the tissue must by both rapid and effective. Since the middle of the last century we have progressively built up a comprehensive... Skeletal muscle is the most abundant tissue of our body. Apart from its essential role in locomotion, it is also the body s main store of carbohydr... |
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585,00 zł |
Morphology Methods: Cell and Molecular Biology Techniques
ISBN: 9780896039551 / Angielski / Twarda / 422 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The past several decades have witnessed an impressive array of conceptual and techno logical advances in the biomedical sciences. Much of the progress in this area has developed directly as a result of new morphology-based methods that have permitted the assessment of chemical, enzymatic, immunological, and molecular parameters at the cellular and tissue levels. Additional novel approaches including laser capture microdissection have also emerged for the acquisition of homogeneous cell popula tions for molecular analyses. These methodologies have literally reshaped the approaches to...
The past several decades have witnessed an impressive array of conceptual and techno logical advances in the biomedical sciences. Much of the progress...
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585,00 zł |
Molecular Biology in Plant Pathogenesis and Disease Management: Microbial Plant Pathogens, Volume 1
ISBN: 9781402082429 / Angielski / Twarda / 249 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Studies on molecular biology of pathogens, infection process and disease resistance, have provided information essentially required to understand the vulnerable stages at which the pathogens can be tackled effectively and to adopt novel strategies to incorporate disease resistance genes from diverse sources and /or to induce resistance of cultivars with desirable agronomic attributes using biotic or abiotic agents. The nature of interaction between the gene products of the pathogen and plant appears to determine the outcome of the interaction resulting in either disease progression or...
Studies on molecular biology of pathogens, infection process and disease resistance, have provided information essentially required to understand the ...
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585,00 zł |
Molecular Biology in Plant Pathogenesis and Disease Management:: Disease Development, Volume 2
ISBN: 9781402082443 / Angielski / Twarda / 246 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Studies on the phenomenon of plant pathogenesis (disease development) have been useful to have a deep insight into the interactions between host plant and the pathogen. Depending on the levels of susceptibility (compatibility) or resistance (incompatibility) of the host plant and virulence of the pathogen, disease development may progress, either leading to symptom expression or result in the suppression of pathogen proliferation. Molecular techniques have been applied to elucidate the nature of interactions between the gene products of the plant and pathogen at cellular and molecular... Studies on the phenomenon of plant pathogenesis (disease development) have been useful to have a deep insight into the interactions between host pl... |
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585,00 zł |
The Golgi Apparatus: State of the Art 110 Years After Camillo Golgi's Discovery
ISBN: 9783211763094 / Angielski / Twarda / 716 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It collects the full range of expertise, different points of view and different approaches. The book is devoted to molecular modes of the function of the Golgi apparatus as a whole, taking into account all experimental data. The book aims to make the functional organization of the Golgi apparatus more understandable. This book summarizes all new data obtained after development of methods of Golgi complex sub fractionation, molecular biology and microscopy. It co... |
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585,00 zł |
Linkage Disequilibrium and Association Mapping: Analysis and Applications
ISBN: 9781588296696 / Angielski / Twarda / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. They provide cutting-edge analysis of the most up-to-date and preeminent information available. As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scien... |
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585,00 zł |
Breast Cancer Chemosensitivity
ISBN: 9780387740379 / Angielski / Twarda / 175 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated... In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer pati... |
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585,00 zł |
Mass Spectrometry of Proteins and Peptides: Methods and Protocols, Second Edition
ISBN: 9781934115480 / Angielski / Twarda / 470 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. When the last edition of this book was published in 2000, the field of proteomics was in its infancy. At that time, multidimensional liquid chromatographic separations were being introduced as an alternative to traditional gel-based techniques for separating complex protein and peptide mixtures prior to mass spectrometric detection. Today, this approach referred to as shotgun proteomics is considered routine for lar- scale global analyses of protein mixtures. Now in its adolescence, proteomics is fundamentally transforming biological and medical research. Much of this transformation can be...
When the last edition of this book was published in 2000, the field of proteomics was in its infancy. At that time, multidimensional liquid chromatogr...
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585,00 zł |