The most recent information on proteins dependent upon Vitamin B6, PQQ or other quinones for function are included in this volume. It is a compilation of recent advances in the understanding of these proteins structures, mechanisms of action, and their biological roles and functions. In addition, the book contains sections devoted to the mechanisms of folding and to addressing the molecular physiology and pathology of these families of proteins, which are of intense biomedical interest. Emerging information regarding the participation of these proteins in enzymatic activity and their...

Since the first international meeting on Vitamin B6 involvement in catalysis took place in 1962, there have been periodic meetings every three or four years. In 1990, scientists studying another cofactor, PQQ, which had already attracted the scientific community's interest for its possible involvement in amino acid decarboxylation and reactions involving amino groups, joined forces with those investigating pyridoxal phosphate-dependent enzymes. Since then, the international PQQ/quinoproteins meetings have been held jointly. In the years following the original meeting 37 years ago in Rome,...