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Protein - Protein Interaction
ISBN: 9783642088384 / Angielski / Miękka / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Individual organisms are de?ned by their genetic code. During development andasaresponsetoexternalstimulithegeneticinformationistranslated into awell-de?nedanswerresultingintheexpressionandmodi?cationofproteins. The processes that control protein protein interactions (PPI) are presently mostly described in terms of individual protein protein interactions. In vivo suchinteractions are partof complex molecular interaction networksthat are highlydynamicintimeandspace.Onthebasisofquantitative experiments, it would be possible to understand such complex biological systems leading to...
Individual organisms are de?ned by their genetic code. During development andasaresponsetoexternalstimulithegeneticinformationistranslated into awell-...
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Chemistry of Opioids
ISBN: 9783642181061 / Angielski / Twarda / 314 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Traials; by K. Kawai and S. Sakami * Twin and Triplet Drugs in Opioid; by H. Fujii * Synthesis of Neoclerodane Diterpenes (Salvinorin Derivatives) and Their Pharmacological Effects; by T. E. Prisinzano * Synthesis of Novel Basic Opioid Skeletons Derived from Naltrexone; by H. Nagase * Nonpeptidic d Opioid Agonists: What Have We Learned?; by S. N. Calderson * Synthesis of 14-Alkoxy- and 14-Aminomorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M....
Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Traials; by K. Kawai and S. Saka...
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Phosphodiesterases as Drug Targets
ISBN: 9783642179686 / Angielski / Twarda / 522 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use...
Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective e...
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Cell Culture Engineering
ISBN: 9783642070518 / Angielski / Miękka / 168 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that...
Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon o...
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Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids
ISBN: 9783642085833 / Angielski / Miękka / 247 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them...
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The ...
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Anthracycline Chemistry and Biology I: Biological Occurence and Biosynthesis, Synthesis and Chemistry
ISBN: 9783642094965 / Angielski / Miękka / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Still valid and useful after up to a decade, this series presents critical reviews of the present position and future trends in modern chemical research. It is made up of short and concise reports on chemistry, each written by the world renowned experts.
Still valid and useful after up to a decade, this series presents critical reviews of the present position and future trends in modern chemical resear...
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Cellular and Molecular Biology of Plant Seed Development
ISBN: 9789048148783 / Angielski / Miękka / 650 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The beginnings of human civili zation can be traced back to the time , ne- ly 12 ,000 years ago , when th e early humans gradually ch anged from a life of hunting and gathering food , to producing food. This beginning of pri- tive agriculture ensured a dependable supply of food , and fostered the living together of people in groups and the development of s o c i e ty. During th is time, plant s e e ds were recognized a s a valuable s o ur c e of food and nutrition , and began to be used for growing plants for food. Ever s i n c e , plant seeds have played an important role in the development...
The beginnings of human civili zation can be traced back to the time , ne- ly 12 ,000 years ago , when th e early humans gradually ch anged from a lif...
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Photosystem I: The Light-Driven Plastocyanin: Ferredoxin Oxidoreductase
ISBN: 9789048170883 / Angielski / Miękka / 713 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book summarizes recent advances made in the biophysics, biochemistry, and molecular biology of the enzyme known as Photosystem I, the light-induced plastocyanin: ferredoxin oxidoreductase. The volume provides a unique compilation of chapters that includes information highlighting controversial issues to indicate the frontiers of research and places special emphasis on methodology and practice for new researchers. This book summarizes recent advances made in the biophysics, biochemistry, and molecular biology of the enzyme known as Photosystem I, the light-in... |
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Signal Transduction Mechanisms
ISBN: 9780792336631 / Angielski / Twarda / 325 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains the proceedings of an International Symposium on Second Messenger Systems - Molecular, Cellular and Behavioural Aspects', which was held at Tobago on June 16-17, 1994.
The interaction of an extracellular agonist (First Messenger) with its plasma membrane receptor leads to the transmission of a signal across the cell membrane and results in the production and/or activation of other signalling molecules (Second Messengers). These Second Messengers control the action of many protein kinases and protein phosphatases and so lead to cellular responses. Although the... This volume contains the proceedings of an International Symposium on Second Messenger Systems - Molecular, Cellular and Behavioural Aspects', which w...
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Biochemistry of Signal Transduction in Myocardium
ISBN: 9780792340676 / Angielski / Twarda / 274 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research on Signal Transduction in Normal and Diseased Myocardium' which was held in Rotterdam at the Faculty of Medicine & Health Sciences of the Erasmus University, June 30 and July 1, 1995.
Diverse and distinct auto-, para-, and endocrine stimuli arriving at the surface of endothelium, smooth muscle cells, cardiomyocytes and fibroblasts within the myocardium, engage cell type-specific receptors, which lead to transmission of signals across the... The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research...
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Biochemical Mechanisms in Heart Function
ISBN: 9780792341185 / Angielski / Twarda / 330 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This special issue of Molecular and Cellular Biochemistry good source of information in this regard. contains original research papers as well as invited reviews We wish to thank all of the contributors for their help and dedicated, on the occasion of the 40th anniversary of the in cooperation. We also wish to thank Mrs. Verona Kuhle for auguration of the Heart Research Group in Beriin-Buch that her secretarial help. We are grateful to Dr. Naranjan S. Dhalla, today forms a part there ofthe Max Delbriick Center for Mo Editor-in-Chief of Molecular and Cellular Biochemistry for his lecular...
This special issue of Molecular and Cellular Biochemistry good source of information in this regard. contains original research papers as well as invi...
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Heterocyclic Polymethine Dyes: Synthesis, Properties and Applications
ISBN: 9783642097904 / Angielski / Miękka / 241 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This treatise pertains to dyes composed of a central polymethine moiety and two cyclic terminal subunits. The polymethine linker can be unsubstituted or substituted, and at least one terminal subunit is a heterocyclic system. The classes of compounds reviewed range from classical cyanines, ?rst s- thesized in the 1850s, to hemicyanines, to styryl dyes, to merocyanines, to coumarinpolymethines, andtosquarylium dyesthatweresynthesized forthe ?rst time in the 1960s. These structurally diverse classes of compounds have one commondenominator, namely electronconjugation that involves the t-...
This treatise pertains to dyes composed of a central polymethine moiety and two cyclic terminal subunits. The polymethine linker can be unsubstituted ...
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Bioactive Heterocycles VI: Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles I
ISBN: 9783642098093 / Angielski / Miękka / 283 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As part of the series Topics in Heterocyclic Chemistry, thisvolumetitledBio- tiveHeterocyclesII presentscomprehensiveandup-to-datereviewsonselected topicsconcerning?avonoidsandanthocyaninsinplants, andheterocyclessuch as bioactive phenothiazines, phenoxazines, and related compounds. The v- ume isseparated into two sections mainly concentrating onthese two topics. There are abundant and diverse ?avonoids with carbohydrates and lipids, alkaloids (betalain alkaloids and other alkaloids), phenols (chromones, c- marins, lignans, quinines, andotherphenolics), terpenoids(monoterpenoids,...
As part of the series Topics in Heterocyclic Chemistry, thisvolumetitledBio- tiveHeterocyclesII presentscomprehensiveandup-to-datereviewsonselected to...
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Biotechnology in China I: From Bioreaction to Bioseparation and Bioremediation
ISBN: 9783642260797 / Angielski / Miękka / 322 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years, biotechnology research and development (R&D) in China has been receiving increasing attention from the world. With the open-door policy of the Chinese government, many international publications (for academia) and large market potential (for industry) constitute the two big reasons for the above phen- enon. Biotechnology has become one of the priorities in Mainland China for so- ing many important problems, such as food supply, health care, environment protection, and even energy. The central government has been implementing a c- ple of programs which cover a wide spectrum in...
In recent years, biotechnology research and development (R&D) in China has been receiving increasing attention from the world. With the open-door poli...
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Reactivity Tuning in Oligosaccharide Assembly
ISBN: 9783642268243 / Angielski / Miękka / 296 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Armed-Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristobal Lopez Armed-Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristobal Lopez |
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Arrestins - Pharmacology and Therapeutic Potential
ISBN: 9783642411984 / Angielski / Twarda / 447 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners. This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing ... |
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Photosynthesis Research for Food, Fuel and Future: 15th International Conference on Photosynthesis
ISBN: 9783642320330 / Angielski / Twarda / 845 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Photosynthesis is the process by which plants, algae and certain species of bacteria transform solar energy into chemical energy in the form of organic molecules. In fact, all life on the planet ultimately depends on photosynthetic energy conversion. The book provides a compressive and state-of-the-art of very recent progress on photosynthesis research. The topics span from atom to intact plants, from femtosecond reactions to season long production, from physics to agronomy. The book is to offer advanced undergraduate students, graduate students, and research specialists the most recent...
Photosynthesis is the process by which plants, algae and certain species of bacteria transform solar energy into chemical energy in the form of organi...
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Cadmium: From Toxicity to Essentiality
ISBN: 9789400751781 / Angielski / Twarda / 560 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use...
Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations,...
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Plastid Development in Leaves During Growth and Senescence
ISBN: 9789400757233 / Angielski / Twarda / 685 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Chloroplast development is a key feature of leaf developmental program. Recent advances in plant biology reveal that chloroplasts also determine the development, the structure and the physiology of the entire plant. The books, published thus far, have emphasized the biogenesis of the organelle, but not the events associated with the transformation of the mature chloroplast to the gerontoplast during senescence. This book, with 28 chapters, is unique because it describes how the chloroplast matures and how it is subsequently transformed to become the gerontoplast during senescence, a... Chloroplast development is a key feature of leaf developmental program. Recent advances in plant biology reveal that chloroplasts also determine th... |
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Sulfur Metabolism in Phototrophic Organisms
ISBN: 9789048177424 / Angielski / Miękka / 518 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Sulfur is one of the most versatile elements in life. This book provides, for the first time, in-depth and integrated coverage of the functions of sulfur in phototrophic organisms including bacteria, plants and algae. It bridges gaps between biochemistry and cellular biology of sulfur in these organisms, and of biology and environments dominated by them. The book therefore provides a comprehensive overview of plant sulfur relations from genome to environment.
Sulfur is one of the most versatile elements in life. This book provides, for the first time, in-depth and integrated coverage of the functions of ... |
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