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Neurogenetics: Scientific and Clinical Advances
ISBN: 9780824729424 / Angielski / Twarda / 792 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Standing at the forefront of neurogenetic medicine, this reference supplies the tools and information required by clinicians to become familiar with modern neurogenetic approaches and apply the data gleaned from these technologies to the diagnosis and treatment of neurogenetic disorders, as well as traditionally non-genetic conditions such as Parkinson's and Alzheimer's disease.
Standing at the forefront of neurogenetic medicine, this reference supplies the tools and information required by clinicians to become familiar with m...
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1114,81 zł |
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Analytical Techniques in DNA Sequencing
ISBN: 9780824753429 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding.
Analytical Techniques in DNA Sequencing takes a look at the various DNA sequencing techniques that were developed and put to use during and after the Human Genome Project. Nunnally makes a special effort to trace the development of this branch of research since the early days of radioisotope sequencing. Special... While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing anal...
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1317,50 zł |
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Neurobehavioral Genetics: Methods and Applications, Second Edition
ISBN: 9780849319037 / Angielski / Twarda / 496 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. Providing solid historical background, the introductory chapters examine past conceptual streams of behavior genetics. Later chapters discuss the applications of quantitative and molecular genetics in basic and clinical research. This edition offers a contemporary approach to the study of the brain and behavior. It also serves as an excellent resource for investigators who want to incorporate genetic methods into...
Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetic...
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912,11 zł |
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DNA Methylation: Approaches, Methods, and Applications
ISBN: 9780849320507 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological...
DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promis...
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1165,48 zł |
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Gaucher Disease
ISBN: 9780849338168 / Angielski / Twarda / 552 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In September of 2007 Gaucher Disease received a commendation in the Haematology category of the 2007 British Medical Association Medical Book Competition
Although rare in the general population, Gaucher disease is the most prevalent of the lysosomal storage disorders, making research into this particular orphan disorder an invaluable prototype for the diagnosis, research, and treatment of others. Like many rare conditions, Gaucher disease has benefited from the explosion of medical research in the last decade, the amount of new information on this disease is staggering and the rate of... In September of 2007 Gaucher Disease received a commendation in the Haematology category of the 2007 British Medical Association Medical Book Competit...
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1266,83 zł |
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Access to the Genome: The Challenge to Equality
ISBN: 9780878406784 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening tests for inherited disorders, gene therapies, and the ability to manipulate a person's inherited, non-disease traits. Most of the attention given to the social implications of these technologies has focused on their potential to harm the individual, for example, by denying employment or insurance. This book explores instead the potential harm to society if we unfairly distribute the enormous benefits of genetic technologies. The resulting... Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening te... |
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256,03 zł |
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Abraham Lincoln's DNA and Other Adventures in Genetics
ISBN: 9780879696498 / Angielski / Miękka / 339 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an eminent physician-lawyer who uses the stories to illustrate the principles of human genetics and to discuss the broader issues.
Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an emin...
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59,75 zł |
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Is It in Your Genes?: The Influence of Genes on Common Disorders and Diseases That Affect You and Your Family
ISBN: 9780879697211 / Angielski / Miękka / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician geneticist, who has given hundreds of lectures on this subject, takes a user friendly approach. Drawing on the many questions he has been asked (for example, My sister has multiple...
One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorder...
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77,66 zł |
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Gene Isolation and Mapping Protocols
ISBN: 9780896034822 / Angielski / Twarda / 318 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past 10 years great progress has been made in the development of efficient techniques for both gene isolation and mapping. The identifica tion and isolation of transcribed sequences from large chromosomal regions are central to the human genome mapping project. Techniques for isolating novel cDNAs have applications both in the overall construction and integra tion of long-range physical and transcription maps and in the identification of disease genes. A number of different techniques for the isolation of cDNAs from mam malian genomes have been developed, including screening "zoo"...
Over the past 10 years great progress has been made in the development of efficient techniques for both gene isolation and mapping. The identifica tio...
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599,56 zł |
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DNA Topoisomerase Protocols: Volume II: Enzymology and Drugs
ISBN: 9780896035126 / Angielski / Twarda / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that catalyze changes in the linkage of DNA strands. DNA topoisomerases are ubiquitous in nature and have been shown to play critical roles in most p- cesses involving DNA, including DNA replication, transcription, and rec- bination. These enzymes further constitute the cellular targets of a number of clinically important antibacterial and anticancer agents. Thus, further studies of DNA topology and DNA topoisomerases are critical to advance our und-...
Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that cataly...
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399,69 zł |
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Neurotrophin Protocols
ISBN: 9780896036994 / Angielski / Twarda / 274 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The past decade has seen an extraordinary growth in research interest in neurotrophic factors, and the study of the neurotrophin family has led this activity. Nevertheless, this area of research has often struggled as a result of techniques that were either inadequate or just emerging from other research fields and disciplines. Neurotrophin Protocols has brought together many leaders in the neurotrophin field who detail their special expertise in a wide variety of techniques. Though most procedures are valid across many diff- ent fields of research, some of those described here have been...
The past decade has seen an extraordinary growth in research interest in neurotrophic factors, and the study of the neurotrophin family has led this a...
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399,69 zł |
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Gene Engineering in Endocrinology
ISBN: 9780896037182 / Angielski / Twarda / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the past five to ten years, a variety of tools has been developed in the disciplines of both gene engineering, and molecular and structural biology. Some of these advances have permitted scientists not only to identify and characterize genes, but also to target these genes by disruption, thus eliminating their function in living animals, and to det- mine the biological responses to altered gene products. This has particular significance in endocrine systems, in which feedback mechanisms between the hypothalamus, pi- itary, and end organs are critical in normal physiology....
During the past five to ten years, a variety of tools has been developed in the disciplines of both gene engineering, and molecular and structural bio...
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799,43 zł |
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DNA Damage and Repair: Advances from Phage to Humans
ISBN: 9780896038035 / Angielski / Twarda / 412 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair...
Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes an...
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599,56 zł |
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Tumor Suppressor Genes in Human Cancer
ISBN: 9780896038073 / Angielski / Twarda / 386 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describing the broad roles of tumor suppressors from a perspective based in molecular biology and genetics, the authors detail the major suppressors and the pathways they regulate, including cell cycle progression, stress responses, apoptosis, and responses to DNA damage. Leading-edge and forward-looking, Tumor Suppressor Genes in Human Cancer illuminates what is currently known of tumor suppressor genes and their regulation, work that is already...
David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describin...
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799,43 zł |
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Gene Probes
ISBN: 9780896038851 / Angielski / Twarda / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Senior scientists Marilena Aquino de Muro and Ralph Rapley have brought together an outstanding collection of time-tested protocols for designing and using genes probes in a wide variety of applications. The applications covered range from searching for specific genes in the human chromosome to the detection of microorganisms and their toxins in the environment and in food samples, as well as in the diagnosis of human disease. Helpful tutorials explain the principles of gene probe design, labeling, detection, target formation, and hybridization conditions.
Senior scientists Marilena Aquino de Muro and Ralph Rapley have brought together an outstanding collection of time-tested protocols for designing and ...
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cena:
399,69 zł |
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Molecular Diagnosis of Genetic Diseases
ISBN: 9780896039322 / Angielski / Twarda / 387 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic diseases. The authors use such methodologies as PCR optimization dosage analysis, mutation scanning, and quantitative fluorescent PCR for aneuploidy analysis, Neurofibromatosis type 1, and Duchenne muscular dystrophy. These largely generic methodologies may be adapted to most genetic conditions for which a molecular diagnosis is relevant, no matter how frequent or rare their incidence. Molecular Diagnosis of Genetic Diseases, Second Edition offers...
This completely revised and updated second edition to integrates the many new technologies and insights now available for the diagnosis of genetic dis...
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cena:
599,56 zł |
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Origin and Evolution of New Gene Functions
ISBN: 9781402013966 / Angielski / Twarda / 199 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Although interest in evolutionary novelties can be that these different mechanisms cooperate in the mak traced back to the time of Darwin, the appreciation ing of new genes. In the second phase of new gene evolution, conventional models of new gene evolution, and systematical experimental pursuit of the origin and evolution of new gene functions did not appear for example by gene duplication, held that the muta until the early years of last decade. Since the 1970s, tions fixed in the early stages of the new genes are Susumu Ohno, Walter Gilbert, and others from the assumed to be neutral or...
Although interest in evolutionary novelties can be that these different mechanisms cooperate in the mak traced back to the time of Darwin, the appreci...
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399,69 zł |
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Genetics and Genomics for the Cardiologist
ISBN: 9781402073090 / Angielski / Twarda / 227 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Genetics and Genomics for the Cardiologist is a concise, but comprehensive volume for the clinical cardiologist or medical student interested in learning how molecular genetics is now being applied to prevention and treatment of heart diseases, from DNA tests to pharmacogenomics and gene-based therapeutics. The volume, written in a plain language, contains detailed figures. A rich glossary, three appendices, many references and several URLs provide additional sources of information.
Genetics and Genomics for the Cardiologist is a concise, but comprehensive volume for the clinical cardiologist or medical student in...
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399,69 zł |
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Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis
ISBN: 9781402073700 / Angielski / Twarda / 335 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to...
It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways....
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cena:
399,69 zł |
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Genomics: Applications in Human Biology
ISBN: 9781405108195 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Written by the successful author team of Sandy Primrose and Richard Twyman, Genomics: Applications in Human Biology is a topical book showing how the new science of genomics is adding impetus to the advances in human health provided by biotechnology.
Written by the successful author team of Sandy Primrose and Richard Twyman, Genomics: Applications in Human Biology is a topical book showing h...
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cena:
442,46 zł |
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