Molecular and Cell Biology of Human Gene Therapeutics
ISBN: 9780412625503 / Angielski / Twarda / 403 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine environment and hence unique response to immune modu lation. A differential response to immunotherapy is thus inevitable. 4. Many of the human trials described are not randomized and report survival or response against historical controls. Most tumors described are immunogenic human tumors: renal cell cancer and melanoma are most common. In order to avoid the well-described inter-patient vari ation and rare incidence of spontaneous response...
advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine...
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cena:
776,43 zł |
The New Genetics and the Public's Health
ISBN: 9780415221429 / Angielski / Miękka / 264 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The rapid advancement of genetic science, fuelled by the Human Genome Project and other related initiatives, promises a new kind of public health practice based on the pre-detection of disease according to calculations of genetic risk.This book by two well-known sociologists explores the implications of the new genetics for public health as a body of knowledge and a domain of practice. It assesses the impact of new genetic information and technologies on conceptions of health, illness, embodiment, self and citizenship and critically examines the complex discourses surrounding human genetics...
The rapid advancement of genetic science, fuelled by the Human Genome Project and other related initiatives, promises a new kind of public health prac...
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146,32 zł |
Stem Cell Biology and Gene Therapy
ISBN: 9780471146568 / Angielski / Twarda / 584 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents stem cells and gene therapy together in one volume. Advances in molecular genetics and recombinant DNA technology have led to the identification of a plethora of disease causing genes. Encouraged by an understanding of the molecular basis of human disease and its connection to genetic changes that result in abnormal structure and function, human gene therapy research for medical therapeutic purposes has emerged as a global drug development effort.
This volume presents stem cells and gene therapy together in one volume. Advances in molecular genetics and recombinant DNA technology have led to the...
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1264,23 zł |
Handbook of Chromosomal Syndromes
ISBN: 9780471372172 / Angielski / Twarda / 376 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Consisting of more than 200 chromosomal aneuploidy syndromes, the Handbook Chromosomal Syndromes is the up-to-date reference to focus exclusively on clinical syndromes due to chromosomal abnormalities. For each syndrome, easy-to-use guide offers a complete description of clinical presentation, with illustrations, as well as information on behavioral aspects, life expectancy, diagnosis, and cytogenetics. Features of the text include:
- A section devoted to the nomenclature of chromosome abnormalities - Pictorial material suitable to be shown to patient populations -... Consisting of more than 200 chromosomal aneuploidy syndromes, the Handbook Chromosomal Syndromes is the up-to-date reference to focus exclusively on c...
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897,63 zł |
An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases
ISBN: 9780471474265 / Angielski / Twarda / 656 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An Introduction to Human Molecular Genetics
Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been... An Introduction to Human Molecular Genetics
Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed te... |
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832,58 zł |
Genetic Testing: Care, Consent and Liability
ISBN: 9780471649878 / Angielski / Twarda / 624 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A complete review of the issues with specific recommendations and guidelines.
With over 1,000 tests commercially available, genetic testing is revolutionizing medicine. Health care professionals diagnosing and treating patients today must consider genetic factors, the risks and limitations of genetic testing, and the relevant law. Genetic Testing: Care, Consent, and Liability offers the only complete, practical treatment of the genetic, clinical, ethical, and legal issue surrounding genetic testing. The authors present protocols, policies, and models of care that are currently in... A complete review of the issues with specific recommendations and guidelines.
With over 1,000 tests commercially available, genetic testi... |
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663,86 zł |
Gene Therapy Technologies, Applications and Regulations: From Laboratory to Clinic
ISBN: 9780471967095 / Angielski / Twarda / 400 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gene therapy is probably the most exciting area of current biomedical research. This volume brings together current data previously separated in health authority and regulatory guidelines, government legislative documents, and primary literature. It combines information on gene therapy technologies and the attendant regulatory requirements for gene therapy products and procedures.
Gene therapy is probably the most exciting area of current biomedical research. This volume brings together current data previously separated in healt...
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1476,75 zł |
The Consequences of Chromosome Imbalance: Principles, Mechanisms, and Models
ISBN: 9780521038096 / Angielski / Miękka / 512 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book considers in detail the mechanisms of a major human problem. Chromosome imbalance affects all stages of life in ways ranging from spontaneous abortion and retardation to behavioural problems and malignancy. Charles J. Epstein concerns himself with how and why a particular chromosome imbalance produces a specific phenotype. His fundamental goal is to connect chromosome aberrations with functional abnormalities in terms of gene expression, developmental and cell biology, and metabolism. Through his examination of this relationship, we learn more about normal development and function....
This book considers in detail the mechanisms of a major human problem. Chromosome imbalance affects all stages of life in ways ranging from spontaneou...
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277,56 zł |
The Ethics of Inheritable Genetic Modification: A Dividing Line?
ISBN: 9780521529730 / Angielski / Miękka / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether these procedures will ever...
Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine...
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cena:
227,08 zł |
The Troubled Helix: Social and Psychological Implications of the New Human Genetics
ISBN: 9780521586122 / Angielski / Miękka / 380 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The availability of increasingly sophisticated information on our genetic makeup presents individuals, and society as a whole, with difficult decisions. Although it is hoped that these advances will ultimately lead the way to the effective treatment and screening of all diseases with a genetic component, at present many individuals agonize over the knowledge that they have or will develop an incurable genetic disease. This book explores and surveys these issues from a variety of perspectives: from personal accounts of individuals coping with the threat of genetic disease, to those of...
The availability of increasingly sophisticated information on our genetic makeup presents individuals, and society as a whole, with difficult decision...
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368,40 zł |
Velo-Cardio-Facial Syndrome : A Model for Understanding Microdeletion Disorders
ISBN: 9780521821858 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Velo-Cardio-Facial Syndrome (VCFS) is a genetic disorder caused by the deletion of part of chromosome 22. It occurs in approximately one in 4000 births and there are now more than 100 physical phenotypic features reported. VCFS affects every major system in the body and this 2005 book was the first to describe its full clinical impact. It has been authored by leading international VCFS clinicians/researchers. The focus is on clinical issues with chapters devoted to psychiatric disorders (with the sufferer showing very high levels of schizophrenia), neuroimaging, speech and language disorders,...
Velo-Cardio-Facial Syndrome (VCFS) is a genetic disorder caused by the deletion of part of chromosome 22. It occurs in approximately one in 4000 birth...
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cena:
499,63 zł |
The Ethics of Inheritable Genetic Modification: A Dividing Line?
ISBN: 9780521822770 / Angielski / Twarda / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether these procedures will ever...
Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine...
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cena:
681,40 zł |
Derailed Evolution
ISBN: 9780595373536 / Angielski / Miękka / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A general genetic catastrophe has been developing during the last 120 years, but mostly after 1950. The HIGH and INCREASING prevalence and HIGH and INCREASING incidence of genetic damage/genetic disorders/genetic diseases all over the world logically prove that we have a general genetic catastrophe (GGe.
A general genetic catastrophe has been developing during the last 120 years, but mostly after 1950. The HIGH and INCREASING prevalence and HIGH and IN...
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cena:
98,08 zł |
Your Genealogy Affects Your Health: Know Your Family Tree
ISBN: 9780595396863 / Angielski / Miękka / 116 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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55,35 zł |
Genetic Polymorphisms and Susceptibility to Disease
ISBN: 9780748408221 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but thorough overview of how allelic gene differences influence disease susceptibility in the human population, and will be a useful reference to researchers across a range of disciplines, for example, oncology, cardiology and immunology . In addition, this book serves as a primer for students first entering the field of genetic research.
Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but ...
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1059,94 zł |
Genetics of Colorectal Cancer for Clinical Practice
ISBN: 9780792321002 / Angielski / Twarda / 187 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic predisposition. Those directly involved in the treatment of patients with cancer of the large bowel are confronted to an increasing degree with the genetic aspects of the disease. In familial and hereditary forms of the disorder periodic screening of the close relatives of the patients can in principle prevent disease and death from colorectal cancer. Presymptomatic diagnosis by means of DNA technology is now possible in many cases of familial...
Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic...
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cena:
776,43 zł |
Gene Therapy for Acute and Acquired Diseases
ISBN: 9780792372684 / Angielski / Twarda / 291 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of gene transfer technology will eventually surmount these limitations.
Gene Therapy for Acute and Acquired Diseases includes selected examples of ongoing studies in molecular genetics... In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and c...
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cena:
388,20 zł |
Genetic Influences on Human Fertility and Sexuality: Theoretical and Empirical Contributions from the Biological and Behavioral Sciences
ISBN: 9780792378600 / Angielski / Twarda / 331 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences on fertility, sexuality, and related processes. Genetic Influences on Human Fertility and Sexuality takes the next step, and presents a number of successful empirical searches for such genetic influence on a broad range of processes, such as puberty, marriage, sexual behavior, and twinning. Employing a broad range of methodological approaches, including molecular and behavioral genetics, this book weaves a new theoretical framework...
Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences...
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cena:
776,43 zł |
Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning
ISBN: 9780792382423 / Angielski / Twarda / 172 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. When first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level of specificity in controlling gene expression. Following this initial enthusiasm, antisense oligonucleotides have been maligned as nonspecific, toxic, and essentially useless. However, application of antisense oligonucleotide technology in the nervous system stands apart from the use of this technique in peripheral systems, largely because of its enormous success. The source of this success remains a matter of some controversy.
Modulating Gene... When first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level of specificit...
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cena:
582,32 zł |
Analysis of Human Genetic Linkage
ISBN: 9780801861406 / Angielski / Twarda / 416 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book. New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to... The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg O... |
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cena:
446,29 zł |