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Gene Therapy Technologies, Applications and Regulations: From Laboratory to Clinic
ISBN: 9780471967095 / Angielski / Twarda / 400 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gene therapy is probably the most exciting area of current biomedical research. This volume brings together current data previously separated in health authority and regulatory guidelines, government legislative documents, and primary literature. It combines information on gene therapy technologies and the attendant regulatory requirements for gene therapy products and procedures.
Gene therapy is probably the most exciting area of current biomedical research. This volume brings together current data previously separated in healt...
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cena:
1424,22 |
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The Consequences of Chromosome Imbalance: Principles, Mechanisms, and Models
ISBN: 9780521038096 / Angielski / Miękka / 512 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book considers in detail the mechanisms of a major human problem. Chromosome imbalance affects all stages of life in ways ranging from spontaneous abortion and retardation to behavioural problems and malignancy. Charles J. Epstein concerns himself with how and why a particular chromosome imbalance produces a specific phenotype. His fundamental goal is to connect chromosome aberrations with functional abnormalities in terms of gene expression, developmental and cell biology, and metabolism. Through his examination of this relationship, we learn more about normal development and function....
This book considers in detail the mechanisms of a major human problem. Chromosome imbalance affects all stages of life in ways ranging from spontaneou...
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cena:
347,56 |
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The Ethics of Inheritable Genetic Modification: A Dividing Line?
ISBN: 9780521529730 / Angielski / Miękka / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether these procedures will ever...
Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine...
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cena:
297,26 |
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The Troubled Helix: Social and Psychological Implications of the New Human Genetics
ISBN: 9780521586122 / Angielski / Miękka / 380 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The availability of increasingly sophisticated information on our genetic makeup presents individuals, and society as a whole, with difficult decisions. Although it is hoped that these advances will ultimately lead the way to the effective treatment and screening of all diseases with a genetic component, at present many individuals agonize over the knowledge that they have or will develop an incurable genetic disease. This book explores and surveys these issues from a variety of perspectives: from personal accounts of individuals coping with the threat of genetic disease, to those of...
The availability of increasingly sophisticated information on our genetic makeup presents individuals, and society as a whole, with difficult decision...
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cena:
361,35 |
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The Ethics of Inheritable Genetic Modification: A Dividing Line?
ISBN: 9780521822770 / Angielski / Twarda / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine, public health and biomedical ethics, have established a distinguished team of scientists and scholars to address the issues from the perspectives of biological and social science, law and ethics, including an intriguing Foreword from Peter Singer. Their purpose is to consider how society might deal with the ethical concerns raised by inheritable genetic modification, and to re-examine prevailing views about whether these procedures will ever...
Is inheritable genetic modification the new dividing line in gene therapy? The editors of this searching investigation, representing clinical medicine...
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cena:
661,14 |
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Derailed Evolution
ISBN: 9780595373536 / Angielski / Miękka / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A general genetic catastrophe has been developing during the last 120 years, but mostly after 1950. The HIGH and INCREASING prevalence and HIGH and INCREASING incidence of genetic damage/genetic disorders/genetic diseases all over the world logically prove that we have a general genetic catastrophe (GGe.
A general genetic catastrophe has been developing during the last 120 years, but mostly after 1950. The HIGH and INCREASING prevalence and HIGH and IN...
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cena:
88,20 |
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Your Genealogy Affects Your Health: Know Your Family Tree
ISBN: 9780595396863 / Angielski / Miękka / 116 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
cena:
49,77 |
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Genetic Polymorphisms and Susceptibility to Disease
ISBN: 9780748408221 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but thorough overview of how allelic gene differences influence disease susceptibility in the human population, and will be a useful reference to researchers across a range of disciplines, for example, oncology, cardiology and immunology . In addition, this book serves as a primer for students first entering the field of genetic research.
Genetic Polymorphisms and Susceptibity to Disease provides a reference for established researchers in genetic research. The book provides a broad but ...
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cena:
1070,92 |
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Genetics of Colorectal Cancer for Clinical Practice
ISBN: 9780792321002 / Angielski / Twarda / 187 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic predisposition. Those directly involved in the treatment of patients with cancer of the large bowel are confronted to an increasing degree with the genetic aspects of the disease. In familial and hereditary forms of the disorder periodic screening of the close relatives of the patients can in principle prevent disease and death from colorectal cancer. Presymptomatic diagnosis by means of DNA technology is now possible in many cases of familial...
Colorectal cancer is a collective term for a heterogeneous group of diseases. In a large proportion of cases, the condition is attributable to genetic...
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cena:
806,99 |
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Gene Therapy for Acute and Acquired Diseases
ISBN: 9780792372684 / Angielski / Twarda / 291 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of gene transfer technology will eventually surmount these limitations.
Gene Therapy for Acute and Acquired Diseases includes selected examples of ongoing studies in molecular genetics... In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and c...
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cena:
403,47 |
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Genetic Influences on Human Fertility and Sexuality: Theoretical and Empirical Contributions from the Biological and Behavioral Sciences
ISBN: 9780792378600 / Angielski / Twarda / 331 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences on fertility, sexuality, and related processes. Genetic Influences on Human Fertility and Sexuality takes the next step, and presents a number of successful empirical searches for such genetic influence on a broad range of processes, such as puberty, marriage, sexual behavior, and twinning. Employing a broad range of methodological approaches, including molecular and behavioral genetics, this book weaves a new theoretical framework...
Recent work in quantitative biology has shown theoretically why Fisher's Fundamental Theorem of Natural Selection does not preclude genetic influences...
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cena:
806,99 |
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Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning
ISBN: 9780792382423 / Angielski / Twarda / 172 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. When first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level of specificity in controlling gene expression. Following this initial enthusiasm, antisense oligonucleotides have been maligned as nonspecific, toxic, and essentially useless. However, application of antisense oligonucleotide technology in the nervous system stands apart from the use of this technique in peripheral systems, largely because of its enormous success. The source of this success remains a matter of some controversy.
Modulating Gene... When first introduced, antisense oligonucleotides were hailed as the long awaited magic bullet that would provide an unprecedented level of specificit...
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cena:
605,23 |
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Genomic Medicine: Articles from the New England Journal of Medicine
ISBN: 9780801879791 / Angielski / Miękka / 208 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. -Fifteen years ago, many questioned the wisdom of sequencing the human genome. There were concerns not only about the technical feasibility of such an effort, but also that its scientific worth would prove too modest to warrant the investment of human and financial capital that the project would require. This collection of essays stands as eloquent testimony to those who overcame such doubts to create, nurture, and finish the sequencing of the human genome in April 2003, a date that will forever stand out in human history. The wide and public availability of the human genome sequence and... -Fifteen years ago, many questioned the wisdom of sequencing the human genome. There were concerns not only about the technical feasibility of such... |
cena:
158,84 |
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The Troubled Dream of Genetic Medicine: Ethnicity and Innovation in Tay-Sachs, Cystic Fibrosis, and Sickle Cell Disease
ISBN: 9780801883262 / Angielski / Miękka / 264 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic difference become entangled with political debates about cultural and group differences in America? Such issues are a conspicuous part of the histories of three hereditary diseases: Tay-Sachs, commonly identified with Jewish Americans; cystic fibrosis, often labeled a -Caucasian- disease; and sickle cell disease, widely associated with African Americans. In this captivating account, historians Keith Wailoo and Stephen Pemberton reveal how these... Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic differen... |
cena:
122,98 |
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Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors
ISBN: 9780824700850 / Angielski / Twarda / 448 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An important new collection of clinical and preclinical reports on genetic therapy, this book describes illustrative examples of diseases in which gene-based interventions are presently plausible, and presents case studies of current research using both synthetic oligonucleotides and biological vectors.
Combining the insights of over 50 contributors, Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors An important new collection of clinical and preclinical reports on genetic therapy, this book describes illustrative examples of diseases in which gen...
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cena:
1460,34 |
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Medical Cytogenetics
ISBN: 9780824719999 / Angielski / Twarda / 728 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A discussion of research findings on many important topics in medical genetics - notably FISH (fluorescent in situ hybridization)-based molecular cytogenetic technologies and spectral karyotyping. Designed for cytogeneticists preparing for the certifying examination in clinical cytogenetics offered by the American Board of Medical Genetics (ABMG).
A discussion of research findings on many important topics in medical genetics - notably FISH (fluorescent in situ hybridization)-based molecular cyto...
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cena:
778,85 |
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Neurogenetics: Scientific and Clinical Advances
ISBN: 9780824729424 / Angielski / Twarda / 792 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Standing at the forefront of neurogenetic medicine, this reference supplies the tools and information required by clinicians to become familiar with modern neurogenetic approaches and apply the data gleaned from these technologies to the diagnosis and treatment of neurogenetic disorders, as well as traditionally non-genetic conditions such as Parkinson's and Alzheimer's disease.
Standing at the forefront of neurogenetic medicine, this reference supplies the tools and information required by clinicians to become familiar with m...
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cena:
1070,92 |
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Analytical Techniques in DNA Sequencing
ISBN: 9780824753429 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding.
Analytical Techniques in DNA Sequencing takes a look at the various DNA sequencing techniques that were developed and put to use during and after the Human Genome Project. Nunnally makes a special effort to trace the development of this branch of research since the early days of radioisotope sequencing. Special... While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing anal...
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cena:
1265,63 |
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Neurobehavioral Genetics: Methods and Applications, Second Edition
ISBN: 9780849319037 / Angielski / Twarda / 496 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. Providing solid historical background, the introductory chapters examine past conceptual streams of behavior genetics. Later chapters discuss the applications of quantitative and molecular genetics in basic and clinical research. This edition offers a contemporary approach to the study of the brain and behavior. It also serves as an excellent resource for investigators who want to incorporate genetic methods into...
Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetic...
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cena:
876,20 |
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DNA Methylation: Approaches, Methods, and Applications
ISBN: 9780849320507 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological...
DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promis...
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cena:
1119,59 |
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