Kategoria BISAC: Medical >> Biostatistics

The approach taken in this book is to studies monitored over time, what the Central Limit Theorem is to studies with only one analysis. Just as the Central Limit Theorem shows that test statistics involving very different types of clinical trial outcomes are asymptotically normal, this book shows that the joint distribution of the test statistics at different analysis times is asymptotically multivariate normal with the correlation structure of Brownian motion ("the B-value") irrespective of the test statistic. The so-called B-value approach to monitoring allows us to use, for different...

Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community.

This book provides an introduction to some of these new methods. The main biological topics treated include sequence...

Clustered survival data are encountered in many scientific disciplines including human and veterinary medicine, biology, epidemiology, public health and demography. Frailty models provide a powerful tool to analyse clustered survival data. In contrast to the large number of research publications on frailty models, relatively few statistical software packages contain frailty models.

It is demanding for statistical practitioners and graduate students to grasp a good knowledge on frailty models from the existing literature. This book provides an in-depth discussion and explanation of...

Das Buch fuhrt schrittweise in die faszinierende Welt statistischer Analysen ein. Es erfordert weder Vorwissen in Statistik noch in einem bestimmten Fachgebiet, nur einige Grundkenntnisse in Mathematik und Neugier auf Daten, die vor allem beobachtete Merkmale von Personen sind. Das Buch enthalt viele Beispiele fur Fragen, die mit Hilfe von Daten beantwortet werden konnen und einfache Zahlenbeispiele fur verschiedene Arten von Analysen. Es ist daher geeignet fur Erstsemester und fur alle, die damit beginnen, sich an Studien zu beteiligen, die Datenanalysen erfordern.

Der...

As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications.

Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized...

This book covers a wide range of recent statistical methods that are of interest to scientists in biostatistics as well as in other related fields such as chemometrics, environmetrics and geophysics. The contributed papers, from internationally recognized researchers, present various statistical methodologies together with a selected scope of their main mathematical properties and their application in a real case study.