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Validated Cleaning Technologies for Pharmaceutical Manufacturing
ISBN: 9781574911169 / Angielski / Twarda / 304 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Written by an expert for those who must design validatable cleaning processes and then validate those processes, this book discusses interdependent topics from various technical areas and disciplines. It shows how each piece of the cleaning process fits into the validation program, making it more defensible in both internal quality audits and external regulatory audits. Designed for use in the overall validation program, the book demonstrates how to build a comprehensive program, and includes discussion and examples of cleaning systems, regulatory requirements, and special topics and issues....
Written by an expert for those who must design validatable cleaning processes and then validate those processes, this book discusses interdependent to...
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1089,27 zł |
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Pharmaceutical Marketing: A Practical Guide
ISBN: 9781574911183 / Angielski / Twarda / 400 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Designed as a practical guide for the pharmaceutical industry, this book covers how to apply cutting-edge marketing concepts and tools to the real-world intricacies of marketing a heavily regulated product whose success is determined not by the actual end-user, but by various industry stakeholders. From creating a worldwide vision that cascades into local tactics to managing a drug portfolio or pricing a particular product, this book guides readers through developing, implementing, and auditing a successful marketing strategy geared specifically to the pharmaceutical industry. It provides...
Designed as a practical guide for the pharmaceutical industry, this book covers how to apply cutting-edge marketing concepts and tools to the real-wor...
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959,60 zł |
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Understanding and Treating Adults with Attention Deficit Hyperactivity Disorder
ISBN: 9781585622214 / Angielski / Miękka / 354 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An estimated seven million American adults have attention deficit hyperactivity disorder. Understanding and Treating Adults With Attention Deficit Hyperactivity Disorder provides accurate, timely information about the nature and treatment of this disorder. Written in a collegial style, this resource combines evidence-based material with clinical experience to address problems in diagnosing and treating adults with ADHD. Dr. Doyle shows how diagnostic and treatment methods in children with ADHD also apply to affected adults. He examines the role of medications, including new agents that... An estimated seven million American adults have attention deficit hyperactivity disorder. Understanding and Treating Adults With Attention Deficit ... |
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343,98 zł |
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Pharmacoethics: A Problem-Based Approach
ISBN: 9781587160356 / Angielski / Miękka / 472 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Due to the changing nature of the practice of pharmacy, today's pharmacists, pharmaceutical scientists, and researchers are faced with an increasing amount of ethical dilemmas. Pharmacoethics: A Problem Based Approach not only introduces the current ethical issues, it also provides decision making tools that can be applied to any ethical issue that may arise in the future.
The authors have identified seven clinical and research ethical competencies that pharmacists will face in their practice: professional responsibility, patient's rights, privacy and confidentiality, truth telling,... Due to the changing nature of the practice of pharmacy, today's pharmacists, pharmaceutical scientists, and researchers are faced with an increasing a...
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518,70 zł |
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Dietary Supplements: Toxicology and Clinical Pharmacology
ISBN: 9781588290144 / Angielski / Twarda / 410 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A treasure trove of uncommon and reliable scientific and clinical information for the toxicity and usefulness of today's leading nonherbal dietary supplements. The supplements detailed were chosen for their popularity, toxicity, and the quantity and quality of information available. Each monograph discusses the history of the compound; its chemical structure; its current and promoted uses, sources, and chemical composition; and its toxicity, pharmacokinetics, and physiological role. Also presented are case reports of adverse effects and interactions, as well as information on reproductive...
A treasure trove of uncommon and reliable scientific and clinical information for the toxicity and usefulness of today's leading nonherbal dietary sup...
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cena:
765,72 zł |
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Chemoinformatics: Concepts, Methods, and Tools for Drug Discovery
ISBN: 9781588292612 / Angielski / Twarda / 524 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the literature, several terms are used synonymously to name the topic of this book: chem-, chemi-, or chemo-informatics. A widely recognized de- nition of this discipline is the one by Frank Brown from 1998 (1) who defined chemoinformatics as the combination of all the information resources that a scientist needs to optimize the properties of a ligand to become a drug. In Brown s definition, two aspects play a fundamentally important role: de- sion support by computational means and drug discovery, which distinguishes it from the term chemical informatics that was introduced at least ten...
In the literature, several terms are used synonymously to name the topic of this book: chem-, chemi-, or chemo-informatics. A widely recognized de- ni...
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574,29 zł |
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Optimization in Drug Discovery
ISBN: 9781588293329 / Angielski / Twarda / 420 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to absorption, distribution, metabolism, elimination (ADME), and toxicity issues. Lead optimization in drug discovery, a process attempting to uncover and correct these defects of drug candidates, is highly beneficial in lowering the cost and time to develop therapeutic drugs by reducing drug candidate failures in development. At present, parallel synthesis combining with high-throughput screening has made it easier to generate highly potent...
Recent analyses of drug attrition rates reveal that a significant number of drug candidates fail in the later stage of clinical development owing to a...
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574,29 zł |
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Bioinformatics and Drug Discovery
ISBN: 9781588293466 / Angielski / Twarda / 456 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the identification of specific drug candidates. The authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situations. Because these technologies are still emergent, each chapter contains an extended introduction that explains the theory and application of the technology and techniques...
A collection of readily reproducible bioinformatic methods to advance the drug discovery process from gene identification to protein modeling to the i...
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cena:
574,29 zł |
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Marijuana and Cannabinoid Research: Methods and Protocols
ISBN: 9781588293503 / Angielski / Twarda / 306 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A cutting-edge collection of readily reproducible in vitro and in vivo methods to elucidate the mechanisms associated with cannabinoid function in health and disease. The techniques can be used in studies across the board from genes to behavior. The molecular neurobiological methods are invaluable in analyzing the structure, the polymorphisms, and the molecular expression of the cannabinoid receptors (CBrs), as well as their association with polysubstance abuse. There are also methods for localizing cannabinoid receptors in different systems, visualizing cannabinoid effects using brain slice...
A cutting-edge collection of readily reproducible in vitro and in vivo methods to elucidate the mechanisms associated with cannabinoid function in hea...
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574,29 zł |
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Natural Products: Drug Discovery and Therapeutic Medicine
ISBN: 9781588293831 / Angielski / Twarda / 386 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal...
A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-perf...
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842,30 zł |
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The Adrenergic Receptors: In the 21st Century
ISBN: 9781588294234 / Angielski / Twarda / 404 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential...
An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of...
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cena:
765,72 zł |
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High Content Screening
ISBN: 9781588297310 / Angielski / Twarda / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. Academic research has been primarily focused on hypothesis-driven research. However, the success of the human genome project, a discovery-driven research approach, has opened the door to adding other types of discovery-driven research to a continuum of research approaches. In contrast, drug discovery research in the pharmaceutical industry has embraced discovery-driven research for many years. A good example has been the discovery of active compounds...
There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. Academic...
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574,29 zł |
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Local Drug Delivery for Coronary Artery Disease: Established and Emerging Applications
ISBN: 9781841840451 / Angielski / Twarda / 608 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The two greatest problems associated with PTCA are abrupt or threatened vessel closure and restenosis, stents were initially thought to be the remedy. Unfortunately, this has not proven so: the material of which the stent is composed, along with stent-induced vascular injury, has led to thrombotic effects. Numerous pharmacological agents have been tested in order to reduce acute thrombosis and the hyperproliferative cellular response. Many of these work. Given that stents are used frequently in the catheter lab, it is no surprise that stents are being used for local drug delivery. Pioneers in...
The two greatest problems associated with PTCA are abrupt or threatened vessel closure and restenosis, stents were initially thought to be the remedy....
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cena:
1556,10 zł |
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The Therapeutic Nightmare: The battle over the world's most controversial sleeping pill
ISBN: 9781853836503 / Angielski / Miękka / 196 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Presents an account of how the psychotropic drug Halcion came onto the market in the UK and the US and how it was subsequently withdrawn in the UK after having serious effects on many patients - such as amnesia, suicidal behaviour and psychosis. The text is a study in the issues and difficulties of controlling the safety of new drugs, the interests at stake, the science involved and the problems confronted both by regulators and consumers.
Presents an account of how the psychotropic drug Halcion came onto the market in the UK and the US and how it was subsequently withdrawn in the UK aft...
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119,25 zł |
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Vienna - A Doctor's Guide: 15 Walking Tours Through Vienna's Medical History
ISBN: 9783211489499 / Angielski / Miękka / 190 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Vienna - medically. One can look at Vienna from this perspective, too. There are traces to be found almost everywhere in the city, as not all that long ago Vienna was, from the viewpoint of medical history, regarded as the "Mecca of Medicine." This book describes a total of 15 walking tours through old medical Vienna. Naturally, these tours are concentrated on the inner city and the ninth district; the former was once the heart of mediaeval Vienna while the Allgemeines Krankenhaus (General Hospital) was established in Alsergrund, as the ninth district is known. However, a number of tours lead...
Vienna - medically. One can look at Vienna from this perspective, too. There are traces to be found almost everywhere in the city, as not all that lon...
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229,69 zł |
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World Spice Plants: Economic Usage, Botany, Taxonomy
ISBN: 9783540222798 / Angielski / Twarda / 592 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite their long tradition spices are subject to international modern scientific research. This has made it necessary to disseminate knowledge to a large audience of interest. The book addresses this need by informing the reader about the complex worldwide use of spice plants. The many spice and aromatic plants are arranged in alphabetical order of their botanical relevance. It includes all species which have been cultivated for the above purposes. It also covers species whose usage has long ceased or which are used only rarely or have become wild. In this respect the author has... Despite their long tradition spices are subject to international modern scientific research. This has made it necessary to disseminate knowledge to... |
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1148,61 zł |
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Sterile Filtration
ISBN: 9783540286257 / Angielski / Twarda / 203 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 1 R. Levy: Types of Filtration.- 2 T. Meltzer: Modus of Filtration.- 3 O.W. Reif: Microfiltration Membranes: Characteristics and Manufacturing.- 4 M. Jornitz: Filter Constructions and Design.- 5 R. Madsen: Filter Validation.- 6 M. Jornitz: Integrity Testing.-
1 R. Levy: Types of Filtration.- 2 T. Meltzer: Modus of Filtration.- 3 O.W. Reif: Microfiltration Membranes: Characteristics and Manufacturing.- 4 M. ...
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1148,61 zł |
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Stereochemical Aspects of Drug Action and Disposition
ISBN: 9783540415930 / Angielski / Twarda / 442 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book aims to guide and inspire drug researchers as they enter the 21st century. Stereochemistry is an essential dimension in pharmacology and should be understood as such by all drug researchers whatever their background. When used as probes or medicines, stereoisomeric drugs offer invaluable insights or innovative therapeutic strategies. The book spans the subject from the molecular to the clinical. The first section on chemical aspects contains chapters on chemical synthesis, analysis, natural products, chiral stability (racemezation) and physical properties. The second section is on...
This book aims to guide and inspire drug researchers as they enter the 21st century. Stereochemistry is an essential dimension in pharmacology and sho...
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540,94 zł |
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South American Medicinal Plants: Botany, Remedial Properties and General Use
ISBN: 9783540419297 / Angielski / Twarda / 492 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Books dealing with medicinal herbs have been forests by man. Furthermore, the knowledge of use ful and medicinal plants is lost as soon as tradition much in demand in the last decade, since interest in the use of 'healing plants' instead of chemistry vanishes through the import of new products from wrapped up in the form of pills has gradually in industrialized countries. Already in 1926, PITTIER creased. Interest in natural methods of healing by regreted that the use as well as the production of medicinal plants advanced with the ecological con indigenous medicinal-herbal products,...
Books dealing with medicinal herbs have been forests by man. Furthermore, the knowledge of use ful and medicinal plants is lost as soon as tradition m...
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cena:
1148,61 zł |
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Interfacial Phenomena in Drug Delivery and Targeting
ISBN: 9783718656332 / Angielski / Twarda / 304 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Interfaces are of vital importance in many fields of application, but the phenomena are hard to visualize, and the theories are often linked to complex mathematical models. This work addresses a range of pharmaceutical issues, ranging from product development to research.
Interfaces are of vital importance in many fields of application, but the phenomena are hard to visualize, and the theories are often linked to comple...
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cena:
1089,27 zł |
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