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Deciphering the Role of Succinate Dehydrogenase in Drug Discovery: SDH in Drug Discovery
ISBN: 9789819668304 / Angielski Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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The Biology of Taurine: Methods and Mechanisms
ISBN: 9780306426650 / Angielski / Twarda / 406 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The book is the outcome of the Symposium held in Firenze-San Miniato (PI), October 6-9, 1986. The symposium was entitled "Sulfur Amino Acids, Peptides and Related Compounds" and was the 7th international symposium on taurine ssnd assooiated substances. It is always difficult to introduce, with the right brevity end emphasis, a topic which has been studied in depth by numerous experte. Nevertheless, I shall do my best to give a historical perspeotive...
I was pleased and at the same time filled with some misgivings when Professors Alberto Giotti end Ryan Huxtable asked me to introduce this book. The b...
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New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control
ISBN: 9780306440359 / Angielski / Twarda / 520 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Marking the 200th National Meeting of the American Chemical Society, The Division of Nuclear Chemistry and Technology hosted a group of about 90 scientists from 15 different countries to discuss the new trends in radiopharmaceutical synthesis, quality assurance and regulatory control. This event took place in Washington, D.C. on August 27-30, 1990. When I first suggested the idea for this symposium, a group of scientists who pioneered the proposed topics offered their help to organize and run such a big task with me. Their names are listed here in appreciation. Thomas E. Boothe Cyclotron...
Marking the 200th National Meeting of the American Chemical Society, The Division of Nuclear Chemistry and Technology hosted a group of about 90 scien...
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Poly(ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications
ISBN: 9780306440786 / Angielski / Twarda / 385 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu. It was the majority opinion of this group that a volume dedicated to biotechnical and biomedical applications of PEG chemistry would enhance research and development in this area. Though the book was conceived at the Honolulu meeting, it is not a proceedings of this symposium. Several groups who did not participate in this meeting are repre- sented in the book, and the book incorporates much work done after the meeting. The book does not...
The idea for this book came from discussions among participants in a symposium on biotechnical applications at the "Pacifichem 89" meeting in Honolulu...
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Advances in Mercury Toxicology
ISBN: 9780306441165 / Angielski / Twarda / 490 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is based on an international meeting organized by the University of Tokyo and the University of Rochester, and is published as one belonging to the series of Rochester International Conferences in Environmental Toxicity. The meeting on "Advances in Mercury Toxicology" was held at the University of Tokyo on August 1 to 3, 1990. The invited papers are published in this book along with an "Overview" chapter that was written by the editors at a meeting held at the University of Rochester on August 1 to 2, 1991. The purpose of the meeting was to assemble leading scientists to discuss...
This book is based on an international meeting organized by the University of Tokyo and the University of Rochester, and is published as one belonging...
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Heparin and Related Polysaccharides
ISBN: 9780306442124 / Angielski / Twarda / 376 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume is a record of a meeting entitled "Heparin and Related Polysaccharides" that was held at the Biomedical Center, Uppsala, Sweden between 1-6 September 1991. The meeting was hosted by U. Lindahl, L. Kjellen and I. Bjork, who were helped in their preparations by a scientific advisory panel that included U. Abildgaard, B. Casu, E. Holmer and D. Lane. Altogether, 230 participants from 18 countries attended the meeting, and most were present to be included in a photograph, which is to be found at the end of this volume. The selection of presentations for inclusion in the Symposia of the...
This volume is a record of a meeting entitled "Heparin and Related Polysaccharides" that was held at the Biomedical Center, Uppsala, Sweden between 1-...
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Phytochemical Resources for Medicine and Agriculture
ISBN: 9780306442452 / Angielski / Twarda / 445 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book was tbe result of a symposium beld at tbe American Cbernical Society meeting in Miami Beacb, Florida, September 10-15, 1989. The symposium was jointly sponsored by Tbe Society for Economfc Botany and tbe American Cbernical Society Food and Natural Product sub division. Tbere were five speakers. During tbe social sessions (mostly over drinks in abotel room), it became obvious tbat, regardless of tbe discipline, we were all speaking tbe same language. Yet, prior to tbe symposium, only a few of tbe participants knew one anotber. We decided to expand tbe symposium into a book. The book...
This book was tbe result of a symposium beld at tbe American Cbernical Society meeting in Miami Beacb, Florida, September 10-15, 1989. The symposium w...
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Botulinum and Tetanus Neurotoxins
ISBN: 9780306444128 / Angielski / Twarda / 689 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Three days in Madison have thoroughly modified my view on clostridial neurotoxins. While still realizing the numerous activating, modifying and protective inputs, I cannot judge the meaningfulness of the meeting impartially. Neither may the reader expect a complete summary of all presentations. Collected in this volume, they speak for themselves without requiring an arbiter. Instead I shall write down my very personal opinions as a researcher who has studied clostridial neurotoxins for nearly 25 years. Comparable conferences have been rare during this time. A comprehensive symposium 4 on C....
Three days in Madison have thoroughly modified my view on clostridial neurotoxins. While still realizing the numerous activating, modifying and protec...
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Alcoholism and Women
ISBN: 9780306449215 / Angielski / Twarda / 472 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 'Solid, plausible, accurate and loaded with pertinent and highly referenced information regarding clinical and basic research in alcholism among women and ethnic groups...an essential text in the libraries of academicians, teachers, clinicians, researchers, and policy makers. The quality and scope of the work are groundbreaking, and it is convenient to have it all in one source.' -American Journal of Psychiatry Volume 12 highlights the remarkable evolution of alcoholism research during the last few years, focusing on gender in alcohol actions and consequences.
'Solid, plausible, accurate and loaded with pertinent and highly referenced information regarding clinical and basic research in alcholism among women...
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Protein Delivery: Physical Systems
ISBN: 9780306453595 / Angielski / Twarda / 433 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Protein and peptide therapeutics currently represent eight of the top 100 prescription pharmaceuticals in the U.S., and biotechnology products are projected to account for 15% of the total US. prescription drug market by 2003. Of the protein and peptide products now on the market, many are administered as daily injections, though several are deliveredby noninvasive routes. For example, desmopressin is delivered as a nasal spray, and deoxyribonuclease I is administered by inhalation. Although cyclosporin A is orally active, as yet there are no general means to confer oral bioava- ability to...
Protein and peptide therapeutics currently represent eight of the top 100 prescription pharmaceuticals in the U.S., and biotechnology products are pro...
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Saponins Used in Traditional and Modern Medicine
ISBN: 9780306453939 / Angielski / Twarda / 606 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. ''A wealth of information...these two volumes will be immensely valuable to anyone having to deal with this difficult group of compounds.'' ---Biochemical Systematics and Ecology, from a review of Saponins Used in Traditional and Modern Medicine and Saponins Used in Food and Agriculture
''A wealth of information...these two volumes will be immensely valuable to anyone having to deal with this difficult group of compounds.'' ---Biochem...
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Cytokines, Stress, and Depression
ISBN: 9780306461354 / Angielski / Twarda / 338 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cytokines had been characterized in the early eighties as communication mole- cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a...
Cytokines had been characterized in the early eighties as communication mole- cules between immune cells, and between immunocytes and other peripheral...
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Biological Reactive Intermediates VI: Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases
ISBN: 9780306466595 / Angielski / Twarda / 728 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, that is, toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair,...
This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolit...
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Development and Manufacture of Protein Pharmaceuticals
ISBN: 9780306467455 / Angielski / Twarda / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this era of biotechnology there have been many books covering the fundamentals of recombinant DNA technology and protein chemistry. However, not many sources are available for the pharmaceutical develop ment scientist and other personnel responsible for the commercialization of the finished dosage forms of these new biopharmaceuticals and other products from biotechnology. This text will help to fill this gap. Once active biopharmaceutical molecules are candidates for clinical trial investigation and subsequent commercialization, a number of other activities must take place while research...
In this era of biotechnology there have been many books covering the fundamentals of recombinant DNA technology and protein chemistry. However, not ma...
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Osteoimmunology
ISBN: 9780387720081 / Angielski / Twarda / 176 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with... A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteocla... |
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Oxidative Stress and Signal Transduction
ISBN: 9780412076817 / Angielski / Twarda / 475 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The...
In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constitu...
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Concise Dictionary of Pharmacological Agents: Properties and Synonyms
ISBN: 9780751404999 / Angielski / Twarda / 342 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The purpose of this dictionary is to provide a convenient and affordable personal desk reference resource. The authors, who have many years experience in pharmacological research, teaching and editing, recognized a need for a single up-to-date volume encompassing material that hitherto could be gathered only from a well-stocked library. This book comprises two main sections: an A-Z listing of drugs and their properties; and a descriptive glossary of technical terms. The level and scope of this reference material will make it essential for pharmacologists and medicinal chemists, from the...
The purpose of this dictionary is to provide a convenient and affordable personal desk reference resource. The authors, who have many years experience...
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Cyclodextrins in Pharmacy
ISBN: 9780792321392 / Angielski / Twarda / 225 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems.
The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with... Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. T...
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The Future of Medicines in Health Care: Scenario Report Commissioned by the Steering Committee on Future Health Scenarios
ISBN: 9780792336242 / Angielski / Miękka / 300 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The future place of medicines in health care is both exciting and uncertain. With an aging population, an increasing number of chronic sick, a growing range of treatment options and a developing European market, the one certainty is that medication patterns will change radically over the next 15 years or so. How the future might look, in terms of quality, volume and cost of pharmacotherapy, is the subject of this report.
Four scenarios for the future are set out, all of which take account of already visible trends. Sobriety in sufficiency envisages rational and restrained... The future place of medicines in health care is both exciting and uncertain. With an aging population, an increasing number of chronic sick, a growing...
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Topical Steroids in Gastroenterology and Hepatology
ISBN: 9780792387893 / Angielski / Twarda / 136 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book, the proceedings of a Falk Workshop on Topical Steroids in Gastroenterology and Hepatology', held in Berlin, Germany, on 14 June 2003, critically discusses the current role of budesonide in gastroenterology, hepatology, surgery and oncology and focuses especially on potential new indications for the use of budesonide. A number of smaller clinical studies and anecdotal case reports with impressive clinical effects are reported in patients with gastrointestinal, hepatic, oncological and surgical problems. In addition, the use of budesonide for the treatment of distal ulcerative...
This book, the proceedings of a Falk Workshop on Topical Steroids in Gastroenterology and Hepatology', held in Berlin, Germany, on 14 June 2003, criti...
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