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Monitoring for Adverse Drug Reactions
ISBN: 9780852008768 / Angielski / Twarda / 152 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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805,10 |
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Long-Term Animal Studies: Their Predictive Value for Man
ISBN: 9780852009314 / Angielski / Twarda / 156 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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805,10 |
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Antidepressants
ISBN: 9780896034693 / Angielski / Twarda / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and genetic approaches that will lead to the development of novel antidepressants. The contributors' critical reviews and commentaries illuminate our understanding of the mechanism(s) responsible for antidepressant action. The book's goal is to move beyond current biogenic amine-based concepts and therapies to the development of new and improved antidepressants that are more effective and have a more rapid onset than current.
In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and...
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805,10 |
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Antifolate Drugs in Cancer Therapy
ISBN: 9780896035966 / Angielski / Twarda / 456 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Antifolates are an important class of anticancer drugs originally developed as anti leu kemic agents, but now used, usually in combination with other drugs, for the treatment of a wide range of tumors, notably carcinomas of the head and neck, breast, germ cell tumors, non-Hodgkin's lymphoma, acute lymphoblastic leukemia, and osteogenic sar comas. 5-Fluorouracil and its prodrugs also target, in part, the folate-dependent enzyme, thymidylate synthase. Furthermore, folate supplementation in the form of leucovorin, modulates 5-fluororuacil activity. 5-Fluorouracil is widely used in the treatment...
Antifolates are an important class of anticancer drugs originally developed as anti leu kemic agents, but now used, usually in combination with other ...
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805,10 |
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Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery
ISBN: 9780896036703 / Angielski / Twarda / 396 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and...
Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the late...
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805,10 |
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Toxicology and Clinical Pharmacology of Herbal Products
ISBN: 9780896037915 / Angielski / Twarda / 325 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The herbai medicine industry is growing at an astounding rate. Trade group estimates suggest that total sales exceeded $4 billion dollars in 1999. Herbai remedies are for sale not just in health food stores, but in supermar kets, drug stores, and even discount warehouses. Along with the proliferation in sales has come a proliferation ofinformation sources. Not all ofthe sources are equally reliable, or even intelligible. Traditional herbalists c1assify thistle and mugwort as "cholagogues," substances used to make the gallbladder con tract and release bile. Medical school graduates are...
The herbai medicine industry is growing at an astounding rate. Trade group estimates suggest that total sales exceeded $4 billion dollars in 1999. Her...
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805,10 |
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Tumor Suppressor Genes in Human Cancer
ISBN: 9780896038073 / Angielski / Twarda / 386 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describing the broad roles of tumor suppressors from a perspective based in molecular biology and genetics, the authors detail the major suppressors and the pathways they regulate, including cell cycle progression, stress responses, apoptosis, and responses to DNA damage. Leading-edge and forward-looking, Tumor Suppressor Genes in Human Cancer illuminates what is currently known of tumor suppressor genes and their regulation, work that is already...
David Fisher, MD, PhD, and an authoritative panel of academic, cutting-edge researchers review and summarize the current state of the field. Describin...
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805,10 |
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Cytokines in the Genesis and Treatment of Cancer
ISBN: 9780896038202 / Angielski / Twarda / 504 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress both in animal models and humans in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the... Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tu... |
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805,10 |
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Glutamate and Addiction
ISBN: 9780896038790 / Angielski / Twarda / 440 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, stimulant, and alcohol addiction. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate affects such addictions and how modifying certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that...
In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, s...
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805,10 |
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Tumor Targeting in Cancer Therapy
ISBN: 9780896039193 / Angielski / Twarda / 463 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Tumor Targeting in Cancer Therapy, Dr. Michel Page and a panel of authoritative experts from the drug industry, clinics, and academia introduce the principles and techniques of tumor targeting and critically survey their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme...
In Tumor Targeting in Cancer Therapy, Dr. Michel Page and a panel of authoritative experts from the drug industry, clinics, and academia introduce the...
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805,10 |
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Environmental Specimen Banking and Monitoring as Related to Banking: Proceedings of the International Workshop, Saarbruecken, Federal Republic of Germ
ISBN: 9780898386219 / Angielski / Twarda / 358 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. There is a great dispar.ity between the ability of the major industrial nations to produce and distribute chemicals and our ability to comprehend the nature and potential severity of unintended consequences for man, his life support systems and the environment generally. Furthermore, the gap between our ability to produce and distribute myriad chemicals and our ability to identify, understand or predict unfavorable environmental impacts may widen. As environmental scientists we are conscious of the interrelatedness, not only of environmental systems, but of nations as well. Materials are...
There is a great dispar.ity between the ability of the major industrial nations to produce and distribute chemicals and our ability to comprehend the ...
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805,10 |
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Calcium Antagonists: Mechanism of Action on Cardiac Muscle and Vascular Smooth Muscle
ISBN: 9780898386554 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. From the Proceedings of the Meeting of the American Section of the International Society for Heart Research (ISHR) at Hilton Head, South Carolina, September 21-24, 1983
From the Proceedings of the Meeting of the American Section of the International Society for Heart Research (ISHR) at Hilton Head, South Carolina, Sep...
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805,10 |
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Relaxin 2000: Proceedings of the Third International Conference on Relaxin & Related Peptides 22-27 October 2000, Broome, Australia
ISBN: 9781402000683 / Angielski / Twarda / 460 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The first international forum on relaxin was a workshop held in Hawaii in 1980. This was followed by the Kroc Foundation conference in Santa Ynes, California in 1981 and then the First International Congress on the Hormone Relaxin in Florence in 1982. After a hiatus of several years, the Second International Congress on the Hormone Relaxin was held in Adelaide in 1994. Since that time, the enormous advances in molecular biology and protein chemistry have led to a stellar growth in relaxin research. Novel sites of action of the hormone have been elucidated, numerous new mammalian primary...
The first international forum on relaxin was a workshop held in Hawaii in 1980. This was followed by the Kroc Foundation conference in Santa Ynes, Cal...
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805,10 |
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Cytokines and Mental Health
ISBN: 9781402073533 / Angielski / Twarda / 426 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplinary and "translational," bringing together information that spans the spectrum from the molecular and cellular levels to the patient and the clinic. Content includes chapters that discuss cytokine pathways in the brain, the neurochemical and neuroendocrine effects of cytokines, and the behavioral effects of cytokines including sickness behavior. These chapters in basic research are followed by a more clinical section that discusses the role of... Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplina... |
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805,10 |
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Medicinal Plants of the World, Volume 3: Chemical Constituents, Traditional and Modern Medicinal Uses
ISBN: 9781588291295 / Angielski / Twarda / 648 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An extraordinary compendium of information on herbal medicine, Medicinal Plants of the World, Volume 3 comprehensively documents the medicinal value of 16 major plant species widely used around the world in medical formulations. The book's exhaustive summary of available scientific data for the plants provides detailed information on how each plant is used in different countries, describing both traditional therapeutic applications and what is known from its use in clinical trials. A comprehensive bibliography of over 3000 references cites the literature available from a wide range of...
An extraordinary compendium of information on herbal medicine, Medicinal Plants of the World, Volume 3 comprehensively documents the medicinal value o...
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the role of microtubules in cell biology, neurobiology, and oncology
ISBN: 9781588292940 / Angielski / Twarda / 587 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I want to thank all who contributed to this first edition for their hard work and professionalism, and especially for their patience. I hope the readers will find this volume as helpful as I have found it. There is no doubt that the family of proteins we call the tubulins and the microtubules that they form when they aggregate are extremely important in the cell and, as we are increasingly learning, important in diseases that afflict so many. This field of investi- tion is a testament to how important both basic and clinical sciences are in understanding disease mechanisms and making inroads...
I want to thank all who contributed to this first edition for their hard work and professionalism, and especially for their patience. I hope the reade...
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805,10 |
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The Adrenergic Receptors: In the 21st Century
ISBN: 9781588294234 / Angielski / Twarda / 404 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential...
An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of...
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805,10 |
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Molecular Targeting in Oncology
ISBN: 9781588295774 / Angielski / Twarda / 748 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice. The volume is divided into five sections that cover the most important elements of drug development. The first section focuses... In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphas... |
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805,10 |
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Transforming Growth Factor-Beta in Cancer Therapy, Volume I: Basic and Clinical Biology
ISBN: 9781588297143 / Angielski / Twarda / 764 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF- in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF- was first isolated and characterized as a dimeric pep tide from both human and bovine sources (1-3), but the entire fieldofTGF- research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF- does not playa central...
Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that i...
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805,10 |
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Transforming Growth Factor-Beta in Cancer Therapy, Volume II: Cancer Treatment and Therapy
ISBN: 9781588297150 / Angielski / Twarda / 786 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Transforming Growth Factor-B in Cancer Therapy, Volume II: Cancer Treatment and Therapy The chapters in this volume confer an abundance of knowledge about the current state ofour understanding oftransforming growth factor-B (TGF-B) in cancer treatment and therapy. Unlike several more traditional positive polypeptide growth factors that stim ulate cellular proliferation, the prototypical TGF-B is now known to inhibit the growth of most normal cell types, including those of epithelial and mesenchymal origin. However, there are examplesofcell types that can be stimulated by TGF-B under certain...
Transforming Growth Factor-B in Cancer Therapy, Volume II: Cancer Treatment and Therapy The chapters in this volume confer an abundance of knowledge a...
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cena:
805,10 |
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