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Pathophysiology of Cardiovascular Disease
ISBN: 9781461350842 / Angielski / Miękka / 648 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions.
This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it. Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated char...
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603,81 |
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Cardiovascular Genomics: New Pathophysiological Concepts: Proceedings of the 2001 European Science Foundation Workshop in Maastricht
ISBN: 9781461353478 / Angielski / Miękka / 275 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Four years ago-in December 1997-the first European Science Foundation Workshop on Cardiovascular Specific Gene Expression was held in Maastricht. It was hardly possible to imagine the progress in the field in those four years. In 1997, gene expression was still an art focused on individual genes; in 200 I, many labs have access to micro-array facilities to determine the expression of thousands of genes simultaneously. In 1997, gene expression was an area of fundamental research in basis molecular biology laboratories; in 200 I, clinical cardiovascular research has incorporated gene expression...
Four years ago-in December 1997-the first European Science Foundation Workshop on Cardiovascular Specific Gene Expression was held in Maastricht. It w...
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805,10 |
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Collateral Circulation: Heart, Brain, Kidney, Limbs
ISBN: 9781461363514 / Angielski / Miękka / 406 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Collateral blood vessels develop by growth of pre or newly formed structures in almost all vascular provinces as a consequence of progressing stenosis of the main artery. These alternative routes of blood supply are potentially able to alter the course of vascular disease. Collateral development is a time consuming process, and arterial stenosis and occlusion often progress faster than growth of the alternative routes.
The authors' ultimate goal is to provide a better understanding of collateral growth in order to pave the way for improving the conditions for these potentially... Collateral blood vessels develop by growth of pre or newly formed structures in almost all vascular provinces as a consequence of progressing stenosis...
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402,53 |
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Pathophysiology of Pain Perception
ISBN: 9781461347804 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Readers have access to legions of books dealing with the molecular, genetic, neurochemical, neurophysiological, neuroanatomical, neuroradiological and psychological aspects of pain as well as with the clinical approaches to pain from various medical disciplines. Why then is it necessary to publish a book on the pathophysiologyofpain perception? Pain can result either from noxious events due to lesions, injuries, diseases, etc., or from disturbances in the system transducing, transforming, and processing the potential pain signal or from an interaction of both. Under certain pathological...
Readers have access to legions of books dealing with the molecular, genetic, neurochemical, neurophysiological, neuroanatomical, neuroradiological and...
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402,53 |
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Potassium Channels in Cardiovascular Biology
ISBN: 9781461354871 / Angielski / Miękka / 899 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology. K+ channels determine or modulate many functions of vascular smooth muscle, endothelial and inflammatory cells, and thus are central to regulation of arterial tone and control of cell proliferation. They are also promising targets for antihypertensive treatments with drugs which open and close specific types of K+ channels, making for an active field of research. With their ability to control vascular tone, voltage-gated...
Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology. K |
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805,10 |
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Growth Factors and Wound Healing: Basic Science and Potential Clinical Applications
ISBN: 9781461273219 / Angielski / Miękka / 366 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The aim of this symposium was to provide basic and clinical investigators with the latest information on the biology of wound healing and tissue repair. Written and edited by eminent experts in the field, the papers cover the general concepts of wound healing; the role of nutrients; endogenous growth factors; clinical applications of growth hormone and IGF-1 therapy; and clinical applications of peptide growth factors.
The aim of this symposium was to provide basic and clinical investigators with the latest information on the biology of wound healing and tissue repai...
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201,24 |
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In Vitro Fertilization and Embryo Transfer: A Manual of Basic Techniques
ISBN: 9781461282884 / Angielski / Miękka / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg interaction. "The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process. The observations of Don Wolf on sperm penetration, the block to polyspermy and, most recently, sperm hyperactivation in the monkey and human, Gregory Kopf's elucidation of the mechanisms of sperm activation during penetration and the reciprocal dialogue between sperm and egg, and Barry Bavister's definition of...
The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg in...
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201,24 |
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Proteases in Tissue Remodelling of Lung and Heart
ISBN: 9781461347866 / Angielski / Miękka / 237 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lung and heart under both physiological conditions and major diseases manifesting in these two organs. The individual chapters have been written by leaders in the field who paid much attention to outline in great detail the role of proteases in the pathogenesis, diagnosis and treatment of disease. Available animal models (of disease, transgenic, or knock-out) are extensively referred to and experimental data obtained thereby are discussed in the... Proteases in Tissue Remodelling of Lung and Heart is unique for its comprehensive presentation of protease function in lu... |
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Human Body Dynamics: Classical Mechanics and Human Movement
ISBN: 9781475773903 / Angielski / Miękka / 316 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A quantitative approach to studying human biomechanics, presenting principles of classical mechanics using case studies involving human movement. Vector algebra and vector differentiation are used to describe the motion of objects and 3D motion mechanics are treated in depth. Diagrams and software-created sequences are used to illustrate human movement.
A quantitative approach to studying human biomechanics, presenting principles of classical mechanics using case studies involving human movement. Vect...
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362,27 |
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Handbook of Pathology and Pathophysiology of Cardiovascular Disease
ISBN: 9781475783681 / Angielski / Miękka / 312 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Autopsy derives from the greek word autopsia, which means act of seeing with one's own eyes. It remains the most objective and accurate method to understand human. disease. Unfortunately, the volume of autopsies in teaching hospitals has decreased dramatically over the past years. The crucial factors that account for this are the recent progress and development of new technologies, especially in diagnostic imaging, immunology, cell biology and genetics. Additionally, the perpetual fear of legal liability by physicians accounts for its further decline. Consequently, physicians and medical...
Autopsy derives from the greek word autopsia, which means act of seeing with one's own eyes. It remains the most objective and accurate method to unde...
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885,61 |
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Nitric Oxide and Infection
ISBN: 9781475786170 / Angielski / Miękka / 518 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has established nitric oxide and related reactive nitrogen intermediates to be important molecular mediators of diverse physiologic processes such as control of vascular tone, regulation of the immune system, and microbial and tumor cell growth. This book contains chapters by the leading researchers in the field and examines the biology and biochemistry of nitric oxide and its role in a variety of specific infections ranging from sepsis,...
Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has estab...
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805,10 |
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Biochemistry of the Eye
ISBN: 9781475794434 / Angielski / Miękka / 476 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. My first introduction to the eye came more than three decades ago when my close friend and mentor, the late Professor Isaac C. Michaelson, convinced me that studying the biochemistry of ocular tissues would be a rewarding pursuit. I hastened to explain that I knew nothing about the subject, since relatively few basic biochemical studies on ocular tissues had appeared in the world literature. Professor Michaelson assured me, however, that two books on eye biochemistry had already been written. One of them, a beautiful monograph by Arlington Krause ( 1934) of Johns Hopkins Hospital, is we II...
My first introduction to the eye came more than three decades ago when my close friend and mentor, the late Professor Isaac C. Michaelson, convinced m...
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885,61 |
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The Role of Oxidative Stress in Neuronal Death
ISBN: 9783662225189 / Angielski / Miękka / 203 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. xidative stress refers to the cytotoxic consequences of reactive oxy- O gen species (ROS) which are generated as by-products of normal or aberrant metabolic processes that utilize molecular oxygen, or changes in protection systems. Thus, generation of ROS is a part of normal life and their interaction with host defense systems appears to exert a sig- nificant influence on the normal and abnormal functioning of the cen- tral nervous system. Oxidative stress could also be a secondary conse- quence of defects in energy metabolism involving mitochondria. A subbtle shift toward the prooxidant...
xidative stress refers to the cytotoxic consequences of reactive oxy- O gen species (ROS) which are generated as by-products of normal or aberrant met...
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402,53 |
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The Biology of Germinal Centers in Lymphoid Tissue
ISBN: 9783662131435 / Angielski / Miękka / 241 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.
This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, repres...
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201,24 |
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Nuclear Factor кb: Regulation and Role in Disease
ISBN: 9789401039833 / Angielski / Miękka / 426 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-kappaB is central to a number of cellular functions including cell proliferation, apoptosis, and cellular differentiation. This transcription factor also plays essential roles in innate and acquired immunity, and its deregulation leads to important human diseases such as inflammation and cancer. Therefore NF-kappaB, together with the signaling pathways leading to its activation, constitute an attractive therapeutic target. This book is the first...
The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-k...
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402,53 |
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Free Radicals and Inhalation Pathology: Respiratory System, Mononuclear Phagocyte System Hypoxia and Reoxygenation Pneumoconioses and Other Granulomat
ISBN: 9783642622014 / Angielski / Miękka / 773 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An encyclopedic summary of the highlights in the field of free radicals in medicine and biology, with a detailed analysis of the extensive recent literature. The text describes results from experimental research work on dust inhalation, hypoxia, and environmental toxicology that uses morphologic methods such as electron microscopy, interference microscopy and time-lapse technqiues in tissue cultures. The volume discusses free radical reactions that are probably involved in the pathogenesis of both physical and chemical environmental hazards. It lists radical scavengers that function as... An encyclopedic summary of the highlights in the field of free radicals in medicine and biology, with a detailed analysis of the extensive recent l... |
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201,24 |
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Reviews of Physiology, Biochemistry and Pharmacology
ISBN: 9783662310502 / Angielski / Miękka / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Protein transport events occurring at the endoplasmic reticulum (ER) of eukaryotic cells and the cytoplasmic membrane of prokaryotic organisms share many similarities. Resident proteins of both membranes span the lipid bilayer once or several times by a-helical stretches and their integration is usually mediated by uncleaved signal-anchor sequences. Proteins that are translocated across either membrane, collectively also termed secretory proteins, harbour cleavable N-terminal signal sequences. Prokaryotic and eukaryotic signal sequences have the same modular structure and are functionally...
Protein transport events occurring at the endoplasmic reticulum (ER) of eukaryotic cells and the cytoplasmic membrane of prokaryotic organisms share m...
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805,10 |
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Veins: Their Functional Role in the Circulation
ISBN: 9784431683872 / Angielski / Miękka / 144 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A bird's eye view of the most recent trends in studies of the venous system are given in this book. It covers the problems related to endothelium-derived relaxing factor (EDRF) and NO in venous relaxation. In addition, it discusses topics such as coronary venous flow velocity patterns, venous capacitance changes in experimental acute heart failure, drug actions including atrial natriuretic peptide (ANP), the effect of baroreflex on the experimentally measured mean circulatory filling pressure (MCFP), hepatic vascular capacitance, human pulmonary "venous" capacitance, human pulmonary venous...
A bird's eye view of the most recent trends in studies of the venous system are given in this book. It covers the problems related to endothelium-deri...
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201,24 |
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Cerebral Ischemia: Molecular and Cellular Pathophysiology
ISBN: 9781475747355 / Angielski / Miękka / 278 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The human brain represents about 2% of the body weight, yet it accounts for approximately 20% of aerobic metabolism. This high dependency on energy-consuming processes is mainly caused by the active transport of ions, which is necessary to compensate for the transmembrane ion currents that are part ofthe complex signaling processes in the brain. Ninety-five percent ofthe brain's ATP is derived from mitochondrial oxidative phosphorylation. Since that organ' s storage capacity for oxygen is minimal, any interruption of oxygen delivery to brain cells willlead to changes in membrane excitability...
The human brain represents about 2% of the body weight, yet it accounts for approximately 20% of aerobic metabolism. This high dependency on energy-co...
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201,24 |
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The Role of Nitric Oxide in Heart Failure
ISBN: 9781475788358 / Angielski / Miękka / 252 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Research on nitric oxide (NO) is a very hot topic since 1998, when three prominent researchers were recognized by Nobel prize awards. Addresses clinically pertinent issues related to nitric oxide in the pathophysiology and therapeutics of heart failure. Chapters written by basic scientists and clinicians to emphasize translation character of research in nitric oxide. An excellent reference source for researchers, practitioners and students. Research on nitric oxide (NO) is a very hot topic since 1998, when three prominent researchers were recognized by Nobel prize awards. Addres... |
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603,81 |
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