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Molecular Genetics and Therapy of Leukemia
ISBN: 9781461285373 / Angielski / Miękka / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of new basic knowledge about the malignant process and about the potential for controlling these malignant diseases. Molecular Genetics and Therapy of Leukemia presents contributions by leading investigators and scientific contributors to such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias, the p-53 suppressor gene and oncogene, hematopoietic stem cells, cytokines, detection of minimal residual disease in acute lymphoblastic leukemia, autologous marrow...
Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of new basic knowledge about the malignant process and ab...
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Drug Resistance
ISBN: 9781461285403 / Angielski / Miękka / 418 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Resistance to treatment represents the final common outcome for far too many patients with cancer. Even our most promising new drugs fall victim to drug resistance. Hormones and newer biological therapies, though safe and active, also lose their activity over time.
In this volume of Drug Resistance, leading investigators in the field have reviewed the most basic mechanisms of drug resistance, and have proposed ways to modulate resistance. This comprehensive volume should be of value for basic and clinical scientists who wish to delve more deeply into this intriguing problem in... Resistance to treatment represents the final common outcome for far too many patients with cancer. Even our most promising new drugs fall victim to dr...
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Anticancer Drug Discovery and Development: Natural Products and New Molecular Models: Proceedings of the Second Drug Discovery and Development Symposi
ISBN: 9781461361183 / Angielski / Miękka / 403 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the publication of these proceedings from the Second Drug Discovery and Development Symposium, this forum has become the main mechanism for bringing together the principal groups involved in both discovering and developing new approaches to the treatment of cancer. This Second Symposium emphasized the types of materials being discovered and their therapeutic activity. This is especially evident in the natural product discovery programs, where unique and active structures are being identified.
The major contributors to the meeting were the investigators participating in the National... With the publication of these proceedings from the Second Drug Discovery and Development Symposium, this forum has become the main mechanism for bring...
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Blood Stem Cell Transplantation
ISBN: 9781461379164 / Angielski / Miękka / 416 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. Some of the applications that stand to impact this field most significantly are based on recent advances in the biological sciences, as demonstrated by the chapters on gene therapy, on the detection of minimal residual disease using molecular techniques, and on the use of radioimmunoconjugates targeting lymphoma and leukemia-associated antigens. Others are the results of clinical observations - e.g., the association between graft-versus-host-...
Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. S...
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Head and Neck Cancer: Basic and Clinical Aspects
ISBN: 9781461358374 / Angielski / Miękka / 304 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Throughout the world, head and neck cancer is a major threat to public health and a significant challenge to both clinicians and basic scientists. Despite extensive efforts in primary prevention, screening, early detection, and therapy, long-term survival rates have not improved substantially in the last three decades. This book covers a wide range of exciting new findings in both clinical and basic sciences as they are relevant to head and neck cancer. These findings have recently enhanced our understanding of head and neck carcinogenesis at the genetic and molecular levels, offering the...
Throughout the world, head and neck cancer is a major threat to public health and a significant challenge to both clinicians and basic scientists. Des...
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Gastrointestinal Oncology
ISBN: 9781461372592 / Angielski / Miękka / 391 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gastrointestinal tract malignancies encompass a spectrum of diseases with marked differences in etiology, incidence, biological behavior, and treatment outcome. The incidence of new gastrointestinal cases recorded yearly for patients residing in the United States is approximately 230,000, representing nearly 20% of all cancer cases. Worldwide, gastrointestinal malignancies are responsible for the largest number of cancer deaths, particularly because of the high incidence of hepatocellular and gastric cancer in other countries.
Gastrointestinal Oncology is directed to those most... Gastrointestinal tract malignancies encompass a spectrum of diseases with marked differences in etiology, incidence, biological behavior, and treatmen...
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Biological and Hormonal Therapies of Cancer
ISBN: 9781461378372 / Angielski / Miękka / 286 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume, Biological and Hormonal Therapies of Cancer, which is part of the series Cancer Treatment and Research, presents selected new information concerning biologic and hormonal therapy of cancer. We have attempted to provide the reader with topics of major interest in a timely fashion. There is renewed interest in biologic therapy of cancer. Two chapters review the role of interferon in the hematologic malignancies and in solid tumors. Vaccine therapies have come to the forefront of cancer therapy re- cently, and two chapters approach different strategies of vaccine therapies; one...
This volume, Biological and Hormonal Therapies of Cancer, which is part of the series Cancer Treatment and Research, presents selected new information...
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Endocrine Neoplasms
ISBN: 9781461379195 / Angielski / Miękka / 450 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Andrew Arnold The past several years have been a time of intense excitement and have brought major advances in the understanding and treatment of endocrine neoplasms. This is therefore an excellent point at which to undertake a broad- based overview of the state of the art in endocrine neoplasia for the Cancer Treatment and Research series. Because of the wide and interdisciplinary readership of this series, our aim for each chapter has been to provide ample background for those not highly familiar with the topic, while emphasizing the most recent advances. Furthermore, the chapters have been...
Andrew Arnold The past several years have been a time of intense excitement and have brought major advances in the understanding and treatment of endo...
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Tobacco and Health
ISBN: 9781461357797 / Angielski / Miękka / 1039 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over 1,100 delegates from a hundred countries attended the 9th World Conference onTobaccoandHealth. Afterfivedaysofdebate, severalimportantresolutionswereadopted unanimously and will be landmarks in the fight against tobacco. This great success is due to three facts which emerged from the discussions: 1. Itappears clearlynowthattherisksassociated withtobaccoaremuchgreaterthan previously assumed. Out of two regular smokers, one will die from a tobacco related disease. 2. Reducing tobacco consumption can be achieved but the data collected in several...
Over 1,100 delegates from a hundred countries attended the 9th World Conference onTobaccoandHealth. Afterfivedaysofdebate, severalimportantresolutions...
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Current Research and Clinical Management of Melanoma
ISBN: 9781461363453 / Angielski / Miękka / 388 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In our environmentally conscious society, reports of an increase in the risk of developing several cancers - including melanoma, lymphoma and lung cancer - have excited great controversy. Of these tumors, melanoma has demonstrated the most spectacular increase, generating a considerable body of research. The justification for this volume is found in the need for an up-to-date review of this research. The book represents a comprehensive review of both current research and clinical management of melanoma, arranged in such a way as to be maximally user-friendly to both the basic...
In our environmentally conscious society, reports of an increase in the risk of developing several cancers - including melanoma, lymphoma and lung c...
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Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury: Proceedings of the 2nd International Conference September 17-21,
ISBN: 9781461365624 / Angielski / Miękka / 799 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas of biology and medicine. The eicosanoids comprise the prostaglandins, thromboxanes and leukotrienes and are products of arachidonic acid, an essential polyunsaturated fatty acid stored in tissue phospholipids. Disturbances of eicosanoids and their metabolic products play a regulatory role in many types of cell injuries and diseases. One of the most exciting areas of eicosanoid research pinpoints their participation in the control of cell...
In recent decades eicosanoids have been attracting an increasing amount of attention as a result of their important physiological roles in many areas ...
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Infectious Complications of Cancer
ISBN: 9781461285274 / Angielski / Miękka / 290 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite the major developments in the therapeutic armamentarium for the treatment of infection, the morbidity and mortality of this complication remains very high in patients with compromised defences. Cancer and its treatment represents a major predisposing condition to a variety of infections. These adverse events are still with us, in spite of much progress in the therapy of infectious disease, since cancer therapy is becoming more aggressive, yet further lowering the host's capacity to cope with infections. Moreover, the pathogens adapt effectively to drugs, and at a pace that might...
Despite the major developments in the therapeutic armamentarium for the treatment of infection, the morbidity and mortality of this complication remai...
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Cytokines: Interleukins and Their Receptors
ISBN: 9781461285281 / Angielski / Miękka / 388 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and abnormal human development. Today, it is apparent that cytokines orchestrate growth from the early embryonic stage to maturity and are responsible for the normal function of virtually every organ system. Furthermore, virtually all disease states have been associated, at least in part, with cytokine aberrations.
In this volume, the editors have brought together internationally known experts in the field of interleukin research to provide a... Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and ...
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Cancer Imaging with Radiolabeled Antibodies
ISBN: 9781461288053 / Angielski / Miękka / 468 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology tex...
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Carcinogenesis and Dietary Fat
ISBN: 9781461288787 / Angielski / Miękka / 492 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Prostaglandins, Leukotrienes, and Cancer is a multi-volume series which focuses on an emerging area of cancer research. In 1968, R. H. Williams first reported that elevated prostaglandin levels are present in human medullary carcinoma. Since that time, the concept that arachidonic acid metabolites may be involved in cancer has expanded to include every aspect of the disease from cell transformation through metastasis. Prostaglandins and leukotrienes are generic terms used to describe a family ofbioactive lipids produced from unsaturated fatty acids (principally from arachidonic acid) via the...
Prostaglandins, Leukotrienes, and Cancer is a multi-volume series which focuses on an emerging area of cancer research. In 1968, R. H. Williams first ...
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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy: Proceedings of the Fifth International Symposium on Platinum and Other Metal C
ISBN: 9781461289678 / Angielski / Miękka / 776 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Proceedings of the Fifth International Symposium, held in Abano Terme (Padova), italy, June 29-July 2, 1987
Proceedings of the Fifth International Symposium, held in Abano Terme (Padova), italy, June 29-July 2, 1987
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Management of Gastric Cancer
ISBN: 9781461367314 / Angielski / Miękka / 387 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gastric cancer has been one of the great malignant scourges affecting man- kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec- tion, and better management techniques with applied clinical research, but the...
Gastric cancer has been one of the great malignant scourges affecting man- kind for as long as medical records have been kept. Until operative resecti...
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Management of Infectious Complication in Cancer Patients
ISBN: 9781475771206 / Angielski / Miękka / 300 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Infection is a major cause of morbidity and mortality in patients with neoplastic disease because of compromised host defenses. These defects result in an increased risk of infection and its complications. The nature of the underlying malignancy, the immunodeficiencies associated with it, and the treatments directed against it are all important determinants of infection. In recent years, the introduction of more intensive chemotherapeutic regimes and the widespread use of bone marrow and peripheral stem cell transplantation have changed the pattern of infection in many patients. Furthermore,...
Infection is a major cause of morbidity and mortality in patients with neoplastic disease because of compromised host defenses. These defects result i...
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Physics and Technology of Hyperthermia
ISBN: 9789401081092 / Angielski / Miękka / 664 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the 1960s a firm rationale was developed for using raised temperatures to treat malignant disease and there has been a continuous expansion of the field ever since. However, a major limitation exists in our ability to heat human tumours, especially those sited deep in the body, with a reasonable degree of temperature uniformity. This problem has resulted in engineers and physicists collaborating closely with biologists and clinicians towards the common goal of developing and testing the clinical potential of this exciting treatment modality. The aim of the physicist and engineer is to...
In the 1960s a firm rationale was developed for using raised temperatures to treat malignant disease and there has been a continuous expansion of the ...
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1207,67 |
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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
ISBN: 9781489907400 / Angielski / Miękka / 546 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a tumor cell's resistance to platinum compounds. Inhibition of this repair system by combination chemotherapy with the excision repair inhibitors HU and Ara-C produces synergistic cell kills and increased levels and persistance of DNA interstrand crosslinks. The studies with cis-DDP and -DDP in combination with UV- induced thymine dimers suggest that there may be competition for DNA repair enzymes between the dimer and the platinum lesion. Whether...
Taken together the data presented in this review, and work by many other investigators, support the notion that DNA excision repair is important in a ...
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