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Renal Cancer: Methods and Protocols
ISBN: 9780896038288 / Angielski / Twarda / 403 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The purpose of Renal Cancer: Methods and Protocols is to introduce the surgeon, clinician, investigator, and research scientist to the basic methods employed in the diagnosis and treatment of renal cancer. Treatment of localized renal cancer is surgical. Treatment of metastasis with resection, radiotherapy, chemotherapy, and immunotherapy has had limited results. Therefore, new avenues of treatment are necessary. In planning this work, I have attempted to incorporate coverage by specialists from a variety of disciplines, each applying their individual expertise in renal cancer therapy. Though...
The purpose of Renal Cancer: Methods and Protocols is to introduce the surgeon, clinician, investigator, and research scientist to the basic methods e...
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cena:
402,53 |
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Cancer of the Lung: From Molecular Biology to Treatment Guidelines
ISBN: 9780896038301 / Angielski / Twarda / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, including a practice-oriented review of its diagnosis, evaluation, and treatment. The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic. The book also elucidates the creation and effective...
Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, inc...
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cena:
603,81 |
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Breast Cancer: A Guide to Detection and Multidisciplinary Therapy
ISBN: 9780896038394 / Angielski / Twarda / 346 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Michael H. Torosian, MD, and a panel of physicians and clinical researchers critically synthesize the wide variety of treatment options available to create a state-of-the-art reference for the management of breast cancer patients. Writing from a multidisciplinary perspective, these authoritative contributors review in the light of the most recent findings the major clinical aspects of breast cancer, including, epidemiology and risk factors, breast imaging, biopsy techniques, breast-conserving surgery and reconstruction, mastectomy, and the latest developments in radiation, hormonal, and...
Michael H. Torosian, MD, and a panel of physicians and clinical researchers critically synthesize the wide variety of treatment options available to c...
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811,88 |
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Gene Therapy of Cancer: Methods and Protocols
ISBN: 9780896038431 / Angielski / Miękka / 645 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the discovery of the molecular structure of genes and the unveiling of the molecular basis of numerous human diseases, scientists have been fas- nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either replace defective nonfunctional genes, or code for therapeutic proteins. This concept has evolved into the rapidly growing field of gene therapy. Even though surgery, radiotherapy, and chemotherapy are widely ava- able and routinely used for cancer treatment, these therapies...
Since the discovery of the molecular structure of genes and the unveiling of the molecular basis of numerous human diseases, scientists have been fas-...
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525,32 |
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Cancer Screening: A Practical Guide for Physicians
ISBN: 9780896038653 / Angielski / Twarda / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Cancer Screening: A Practical Guide for Physicians, a panel of highly experienced clinicians and researchers from around the world present their up-to-date screening techniques for a wide variety of cancers. The techniques range from screening for breast, gynecological, and gastrointestinal cancers, to testing for urogenital, dermatological, and respiratory cancers. In addition to providing the busy practitioner with quick access to guidelines for particular cancers, the epidemiology and biology of the various cancers, as well as the sensitivity and specificity of the methods, are...
In Cancer Screening: A Practical Guide for Physicians, a panel of highly experienced clinicians and researchers from around the world present their up...
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603,81 |
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Melanoma: Biologically Targeted Therapeutics
ISBN: 9780896038769 / Angielski / Twarda / 388 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Strategies of treatment involving therapeutic proteins, irnrnune immune cells, or cel lular protein targets are those of greatest potential for further reducing mortality from melanoma. Therapeutic proteins or cells may inhibit melanoma cell growth either by augmentation of immune cell function or by inhibition of angiogenesis. Cytokines and melanoma antigens may be used either in vivo as a vaccine to stimulate irnrnune immune cell cell function or ex vivo to stimulate or proliferate cells for infusion. Alternatively, alteration in melanoma cell growth can occur through inhibition of protein...
Strategies of treatment involving therapeutic proteins, irnrnune immune cells, or cel lular protein targets are those of greatest potential for furthe...
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cena:
254,57 |
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Chronic Leukemias and Lymphomas: Biology, Pathophysiology, and Clinical Management
ISBN: 9780896039070 / Angielski / Twarda / 342 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Chronic Leukemias and Lymphomas: Clinical Management, a panel of recognized experts in hematological oncology describe the unique biological features of indolent hematologic neoplasms, providing powerful insight into their clinical manifestation, highlighting potential targets for novel therapies, and distinguishing these disorders from aggressive lymphoma and Hodgkin's disease. In their integrated surveys of these chronic myeloproliferative and lymphoproliferative disorders, the authors emphasize such unique entities as prolymphocytic leukemias and cutaneous lymphomas. Special emphasis is...
In Chronic Leukemias and Lymphomas: Clinical Management, a panel of recognized experts in hematological oncology describe the unique biological featur...
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811,88 |
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Recombinant Antibodies for Cancer Therapy: Methods and Protocols
ISBN: 9780896039186 / Angielski / Twarda / 481 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the advent of hybridoma technology more than two decades ago, numerous antibodies have entered the clinical setting as potent therapeutic agents. Their repeated application in humans, however, is limited by the development of human antimouse antibodies (HAMA) in the recipient, leading to allergic re- tions against the foreign murine protein and rapid neutralization. To circumvent these limitations many new antibodies have recently been tailored through recombinant antibody technology. The initial clinical data show encouraging results, thus demonstrating the potential of these new...
Since the advent of hybridoma technology more than two decades ago, numerous antibodies have entered the clinical setting as potent therapeutic agents...
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811,88 |
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Tumor Targeting in Cancer Therapy
ISBN: 9780896039193 / Angielski / Twarda / 463 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Tumor Targeting in Cancer Therapy, Dr. Michel Page and a panel of authoritative experts from the drug industry, clinics, and academia introduce the principles and techniques of tumor targeting and critically survey their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme...
In Tumor Targeting in Cancer Therapy, Dr. Michel Page and a panel of authoritative experts from the drug industry, clinics, and academia introduce the...
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cena:
1050,68 |
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Lung Cancer: Volume 2: Diagnostic and Therapeutic Methods and Reviews
ISBN: 9780896039209 / Angielski / Twarda / 816 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This work, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, in the Methods in Molecular Medicine series presents an overview of the current status of those methods useful in the diagnosis and tre- ment of lung cancer--both as it exists in the clinic and as it is being revoluti- ized in the laboratory. The book is intended to serve as a resource for researchers wishing to increase their knowledge of current and cutting edge technologies, in order that their investigations into neoplasms of the lung may benefit from this enriched diversity of techniques and approaches....
This work, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, in the Methods in Molecular Medicine series presents an overview of ...
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811,88 |
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Colorectal Cancer: Multimodality Management
ISBN: 9780896039353 / Angielski / Twarda / 854 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The rapid growth in the number of options available for the management of colorectal cancer presents the clinician with new opportunities and new complexities. An explosion of understanding in the basic science that underlies both the disease and its potential therapies has translated into remarkable technological advances that can now be applied. So many specialties and subspecialties have now been brought to bear that it is appropriate to attempt to bring the expertise from these areas together in one volume, so that practitioners in one aspect of colorectal cancer management can maintain...
The rapid growth in the number of options available for the management of colorectal cancer presents the clinician with new opportunities and new comp...
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cena:
1127,15 |
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Targets for Cancer Chemotherapy: Transcription Factors and Other Nuclear Proteins
ISBN: 9780896039384 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Targets for Cancer Chemotherapy: Transcription Factors and Other Nuclear Proteins, a panel of leading basic researchers, pharmaceutical scientists, and clinical oncologists explain in detail the therapeutically-relevant protein targets that contribute to cancer pathology and spell out their implications for cancer drug discovery and clinical application. The authors identify and illuminate selected transcription factor oncoproteins and tumor suppressors, together with nuclear proteins that are central to the phenotype of the tumor cell involved in chromatin control. The emphasis is on new...
In Targets for Cancer Chemotherapy: Transcription Factors and Other Nuclear Proteins, a panel of leading basic researchers, pharmaceutical scientists,...
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811,88 |
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Novel Anticancer Drug Protocols
ISBN: 9780896039636 / Angielski / Twarda / 355 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxicities that have been the hallmark of conventional cytotoxic cancer chemotherapy. Advances in cancer cell biology fueled by the molecular biology revolution have resulted in the uncovering of many novel potential molecular targets for cancer therapy. New anticancer drug discovery and development is now largely focused on exploiting these new molecular targets, which encompass oncogenes, tumor s- pressor genes, and their gene products, as well as...
We are in an exciting era in the war against cancer, with real prospects for novel anticancer drugs that are cancer cell-specific without the toxiciti...
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811,88 |
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Leukemia and Lymphoma: Detection of Minimal Residual Disease
ISBN: 9780896039667 / Angielski / Twarda / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for leukemias and lymphomas. They apply reverse transcription PCR (RT-PCR) to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for Non-Hodgkin's Lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute...
In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they...
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cena:
525,32 |
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Suicide Gene Therapy: Methods and Reviews
ISBN: 9780896039711 / Angielski / Twarda / 572 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Gene therapy has expanded rapidly over the last decade. The number of clinical trials reported by 2001 included 532 protocols and 3436 patients. Phase I trials predominate with 359 trials of 1774 patients versus Phase II (57 trials with 507 patients) and Phase III (3 trials of 251 patients). The disease overwhelmingly targeted by gene therapy is cancer: involving 331 trials with 2361 patients. Despite the somewhat disappointing results of clinical trials to date, gene therapy offers tremendous promise for the future of cancer therapy. The area of gene therapy is vast, and both malignant and...
Gene therapy has expanded rapidly over the last decade. The number of clinical trials reported by 2001 included 532 protocols and 3436 patients. Phase...
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cena:
811,88 |
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Oncogene-Directed Therapies
ISBN: 9780896039827 / Angielski / Twarda / 487 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic...
Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clin...
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cena:
811,88 |
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Lung Cancer: Volume 1: Molecular Pathology Methods and Reviews
ISBN: 9780896039858 / Angielski / Twarda / 594 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Methods in Molecular Medicine series is intended as a resource for both novice and experienced investigators attempting to diversify their tech- logical base in research. Lung Cancer: Volume 1: Molecular Pathology Me- ods and Reviews presents an overview of the current status of assays employed to detect and characterize the multitude of pathologies that contribute to the development of this deadly disease. As with all volumes in the Methods in Molecular Medicine series, the reader should find that each methods-based chapter provides clear instructions for the performance of various...
The Methods in Molecular Medicine series is intended as a resource for both novice and experienced investigators attempting to diversify their tech- l...
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811,88 |
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Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies
ISBN: 9780896039865 / Angielski / Twarda / 520 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emphasis shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and tumor suppressor genes function in the same pathways, providing positive and ne- tive growth regulatory activities. The signaling pathways controlled by these genes involve virtually...
It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive...
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cena:
603,81 |
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Tumor Suppressor Genes: Volume 2: Regulation, Function, and Medicinal Applications
ISBN: 9780896039872 / Angielski / Twarda / 657 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It has become clear that tumors result from excessive cell proliferation and a corresponding reduction in cell death caused by the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emp- sis has shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and TSGs function in the same pathways, providing positive and negative growth regulatory activities. The signaling pathways controlled by these genes involve virtually every process in cell...
It has become clear that tumors result from excessive cell proliferation and a corresponding reduction in cell death caused by the successive accumula...
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cena:
603,81 |
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Immunologic Approaches to the Classification and Management of Lymphomas and Leukemias
ISBN: 9780898383553 / Angielski / Twarda / 290 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general on cology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure...
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general on cology te...
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cena:
1050,68 |
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