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Cytotoxic T-Lymphocytes in Human Viral and Malaria Infections
ISBN: 9783642785320 / Angielski / Miękka / 210 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice. In this volume, data for the role that CTL play in human infectious diseases is presented. As such, this represents the first volume in which such information from several different viral and protozoan infections is brought together.
Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of ...
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402,53 |
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Simian Immunodeficiency Virus
ISBN: 9783642785382 / Angielski / Miękka / 241 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Interest in the lentivirus subfamily of retroviruses has greatly intensified due to the realization that HIV-1 and HIV-2 are members of this previously obscure group. Related lentiviruses have now been isolated from sheep, goats, horses, cattle, cats, monkeys, and humans. This issue of CTMI is devoted to the lentiviruses of nonhuman primates, referred to as simian immunodeficiency viruses (SIVs). The SIVs provide valuable tools for our quest to understand and control the HIVs, which are obviously important new human pathogens. Included in this volume are discussions of the distribution and...
Interest in the lentivirus subfamily of retroviruses has greatly intensified due to the realization that HIV-1 and HIV-2 are members of this previousl...
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402,53 |
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Bacterial Pathogenesis of Plants and Animals: Molecular and Cellular Mechanisms
ISBN: 9783642786266 / Angielski / Miękka / 343 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The last decade has seen an explosion in our understanding of how bacterial pathogens trick, cajole, usurp and parasitize their various hosts. This renaissance is due to the convergence of molecular and cellular techniques with the power of microbial genetics. The purpose of this volume is to introduce recent advances in understanding selected systems chosen from both plant and animal hosts of bacterial pathogens. This somewhat nonobvious choice of topics was spurred by the recent findings, detailed by several conributors to this volume, of common systems used to secrete virulence factors...
The last decade has seen an explosion in our understanding of how bacterial pathogens trick, cajole, usurp and parasitize their various hosts. This re...
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402,53 |
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The Role of Nitric Oxide in Physiology and Pathophysiology
ISBN: 9783642791321 / Angielski / Miękka / 90 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Nitric Oxide (NO) an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neuro-transmitter like role in vascular endothelium, a scond-messenger role in N-methyl-D-aspartate (NMDA) responsive neurons in the central nervous system (CNS), a neurotoxic role after its release from these neurons, and a cytotoxic role after its release by macrophages.
This volume reviews among other topics the basic chemistry and physical properties of S-nitrosothiols (RS-NO) and their biochemical mechanisms of action, NO synthase isozymes, NO synthase... Nitric Oxide (NO) an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neuro-transmitter li...
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201,24 |
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Tuberculosis
ISBN: 9783642801686 / Angielski / Miękka / 307 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Tuberculosis has plagued mankind since prehistoric times and is still an important source of morbidity and mortality, with particularly devastating effects in developing and tropical countries. Tuberculosis results from an infection with Myeo- baeterium tubereu/osis, and the World Health Organization estimates that perhaps as much as one-third of the world's population or approximately 1. 9 billion persons are or have been infected with M. tubereu/osis. Each year, there are 8-10 million new cases of tuberculosis and about 3 million deaths due to it. Indeed, tuberculosis is the leading cause...
Tuberculosis has plagued mankind since prehistoric times and is still an important source of morbidity and mortality, with particularly devastating ef...
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402,53 |
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DNA Vaccination/Genetic Vaccination
ISBN: 9783642804779 / Angielski / Miękka / 198 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec- tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene- delivered antigen. The recent demonstration by a number of laboratories that the induced immune responses are functional in experimental models against...
Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec- tion of nucleic acid expressio...
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402,53 |
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Peritrophic Membranes
ISBN: 9783642844164 / Angielski / Miękka / 238 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Peritrophic membranes are secretion products of the midgut. For long they have been related only to insects, but they occur widely in the animal kingdom. They effect a part of the gut lumen and function not only as a mechanical protection barrier, but also as an ultrafilter, a barrier to parasites, and as envelopes for fecal pellets. Such peritrophic envelopes are of great ecological importance in marine environments. The book is divided into the following themes: - Occurrence - Formation and Structure - Degradation - Chemical Composition - Functions. It is the first comprehensive compilation...
Peritrophic membranes are secretion products of the midgut. For long they have been related only to insects, but they occur widely in the animal kingd...
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402,53 |
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Breast Cancer Metastasis and Drug Resistance: Progress and Prospects
ISBN: 9781461456469 / Angielski / Twarda / 416 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volumecomprehensivelycovers recent prrogress in breast cancer research. In an effort to successfully treat breast cancer, it is imperative to a) fully understand the disease with all its heterogeneity, b) understand the factors that influence the metastasis of breast cancer to distant organs making it lethal and c) understand the underlying processes that lead to the phenomenon of drug-resistance making the disease particularly incurable.The book explores all of these issues, includingthe phenomenon of epithelial-mesenchymal-transition, cancer stem cells as well as microRNAs in an...
This volumecomprehensivelycovers recent prrogress in breast cancer research. In an effort to successfully treat breast cancer, it is imperative to a) ...
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Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines
ISBN: 9783642641947 / Angielski / Miękka / 296 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Mucosal immunity encompasses a broad field of research that includes areas of epithelial cell and molecular biology, molecular and cellular immunology, microbiology, virology, and vaccinology. This volume presents up to date and concise discussions of concepts as well as recent advances. It provides an overview of the components of the mucosal immune system, and the basic science relevant to mucosal vaccination. The authors assess current research in critical areas including: Organization of mucosal lymphoid tissue; antigen sampling and presentation in mucosal tissues; mucosalimmune responses...
Mucosal immunity encompasses a broad field of research that includes areas of epithelial cell and molecular biology, molecular and cellular immunology...
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Vaccines
ISBN: 9783642641961 / Angielski / Miękka / 534 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The immune system is the only organ system in the body besides the central nervous systems endowed with memory. Both types of memories are specific and long-lasting, sometimes life long. This memory capacity of the immune system provides the basis for the most cost-efficient of all medical interventions, successful vaccinations against many common infectious diseases. Such a success requires the isolation of the infectious agent or toxic substance, methods to grow and/or purify the relevant antigen and change it into something innocuous whilst maintaining its immunogenicity. Whereas the early...
The immune system is the only organ system in the body besides the central nervous systems endowed with memory. Both types of memories are specific an...
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402,53 |
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Helicobacter Pylori: Basic Mechanisms to Clinical Cure 1996
ISBN: 9789401072991 / Angielski / Miękka / 420 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The impact of Helicobacter pylori on basic science and the clinical management of patients with the complications of this infection is bewildering. The explosion of new information both in the laboratory and at the bedside has progressed at an unprecedented rate. Our main objective in furthering this progress has been to integrate this new information and organize a series of top quality presentations and discussions between investigators and clinicians on all aspects of H. pylori research and to review the current position and future research directions. To that end, the second meeting...
The impact of Helicobacter pylori on basic science and the clinical management of patients with the complications of this infection is bewildering. Th...
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805,10 |
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v-Myb proteins and their oncogenic potential: A study on how two point mutations affect the interaction of v-Myb with other proteins
ISBN: 9783656200055 / Angielski / Miękka / 124 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Master's Thesis from the year 2011 in the subject Biology - Micro- and Molecular Biology, grade: 1,0, University of Munster (Institut fur Biochemie), language: English, abstract: The oncogene v-myb of the retroviruses AMV (avian myeloblastosis virus) and E26 (avian leukaemia virus) encodes a transcription factor (v-Myb) which is a truncated homolog of its cellular progenitor c-Myb. c-Myb plays an essential role in the development of haematopoietic cells and is known to be a regulator for many target genes. v-Myb AMV is responsible for the transformation of myelomonocytic cells and arrests...
Master's Thesis from the year 2011 in the subject Biology - Micro- and Molecular Biology, grade: 1,0, University of Munster (Institut fur Biochemie), ...
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301,33 |
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The Hippo Signaling Pathway and Cancer
ISBN: 9781461462194 / Angielski / Twarda / 354 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many leading scientists are showing increased interest in this growing field and it's relation to cancer. The chapters in this volume cover virtually all aspects of tumor biology, because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Ras, Wnt, TGFbeta and p53. Moreover, Hippo signaling is not solely involved in regulating "classic" tumor characteristics such as cell...
The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many lead...
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603,81 |
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Biosystems Engineering I: Creating Superior Biocatalysts
ISBN: 9783642264764 / Angielski / Miękka / 250 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. -Integration of Systems Biology with Bioprocess Engineering: L-Threonine Production by Systems Metabolic Engineering of Escherichia Coli, By Sang Yup Lee and Jin Hwan Park; -Analysis and Engineering of Metabolic Pathway Fluxes in Corynebacterium glutamicum, By Christoph Wittmann; -Systems Biology of Industrial Microorganisms, Marta Papini, Margarita Salazar, and Jens Nielsen; -De Novo Metabolic Engineering and the Promise of Synthetic DNA, By Daniel Klein-Marcuschamer, Vikramaditya G. Yadav, Adel Ghaderi, and Gregory N. Stephanopoulos; -Systems Biology of Recombinant Protein Production in...
-Integration of Systems Biology with Bioprocess Engineering: L-Threonine Production by Systems Metabolic Engineering of Escherichia Coli, By Sang Yup ...
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1207,67 |
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Multi-Drug Resistance in Cancer
ISBN: 9781617796647 / Angielski / Miękka / 492 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug...
Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely lim...
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603,81 |
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Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids
ISBN: 9781468439854 / Angielski / Miękka / 708 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. This was the first meeting of its kind in the Southern Hemisphere. The meeting place was selected for its relaxed and comfortable climate, conducive to interactions among participants. More importantly the locale facilitated the participation of nearby Latin American clinical and research scientists who deal directly with the health manifestations of pathogenic p1asmids. Diseases and socio-economic practices of developing countries exist in...
This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic...
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402,53 |
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General and Applied Aspects of Halophilic Microorganisms
ISBN: 9781461366607 / Angielski / Miękka / 402 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During recent years the subject of extreme environments and extremophiles has become a central topic in modern Biology. The capability of some microorganisms to withstand, and often prefer, the harsh conditions found in such environments is helping to define the physicho-chemicallimits of life and in consequence its essential nature. Halophiles are one of the most representative types of extremophiles, requiring high concentrations of inorganic salts, mostly sodium chloride, to grow and survive. They inhabit hypersaline environments, the distribution and abundance of which dur ing geological...
During recent years the subject of extreme environments and extremophiles has become a central topic in modern Biology. The capability of some microor...
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201,24 |
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Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I
ISBN: 9783642627200 / Angielski / Miękka / 444 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by...
It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose product...
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603,81 |
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Origin and Evolution of the Vertebrate Immune System
ISBN: 9783642640780 / Angielski / Miękka / 326 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop- ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte- brates, the general answer has been...
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in inver...
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603,81 |
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Lactic Acid Bacteria: Genetics, Metabolism and Applications: Proceedings of the Fifth Symposium Held in Veldhoven, the Netherlands, 8-12 September 199
ISBN: 9789401072922 / Angielski / Miękka / 266 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The last decade has seen an explosive increase in the volume of research on and knowledge of lactic acid bacteria, organisms of prime importance for the production of dairy products and the fermentation of various vegetables. This issue of Antonie van Leeuwenhoek, written by international experts in the field, documents these recent exciting developments with respect to genetics, metabolism and application of lactic acid bacteria for industrial and potential medical applications. This book is essential for all researchers with an interest in the fundamental biology of Gram-positive...
The last decade has seen an explosive increase in the volume of research on and knowledge of lactic acid bacteria, organisms of prime importance for t...
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603,81 |
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