Atomic Force Microscopy, Scanning Nearfield Optical Microscopy and Nanoscratching: Application to Rough and Natural Surfaces
ISBN: 9783642066634 / Angielski / Miękka / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Making a clear distinction is made between nano- and micro-mechanical testing for physical reasons, this monograph describes the basics and applications of the supermicroscopies AFM and SNOM, and of the nanomechanical testing on rough and technical natural surfaces in the submicron range down to a lateral resolution of a few nm. New or improved instrumentation, new physical laws and unforeseen new applications in all branches of natural sciences (around physics, chemistry, mineralogy, materials science, biology and medicine) and nanotechnology are covered as well as the sources for pitfalls...
Making a clear distinction is made between nano- and micro-mechanical testing for physical reasons, this monograph describes the basics and applicatio...
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cena:
780,00 zł |
Recent Advances in Thrombosis and Hemostasis
ISBN: 9784431998518 / Angielski / Miękka / 643 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hypertension, and obesity are the leading causes of morbidity and mortality. They have become urgent medical problems with serious economic consequences in industrialized and devel- ing countries alike. At the same time, the impact of molecular biology and genetics on our understanding of thrombosis and hemostasis is rapidly growing stronger as well as our knowledge of regeneration and development of specific tissues, organs, and embryos....
Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hyp...
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cena:
780,00 zł |
Visualizing Immunity
ISBN: 9783642101014 / Angielski / Miękka / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Understanding immune complexity in diverse tissue environments is a challenge for researchers. However, advances in imaging have greatly improved our ability to probe the immune system. This volume provides a synopsis of major insights in immunology revealed using imaging approaches.
Understanding immune complexity in diverse tissue environments is a challenge for researchers. However, advances in imaging have greatly improved our ...
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780,00 zł |
Non-Protein Coding Rnas
ISBN: 9783642089800 / Angielski / Miękka / 398 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows "RNA" Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation,...
The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which foll...
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cena:
780,00 zł |
Standardization and Quality Assurance in Fluorescence Measurements II: Bioanalytical and Biomedical Applications
ISBN: 9783642089503 / Angielski / Miękka / 564 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Analytical chemists and materials scientists will find this a useful addition to their armory. The contributors have sought to highlight the present state of affairs in the validation and quality assurance of fluorescence measurements, as well as the need for future standards. Methods included range from steady-state fluorometry and microfluorometry, microscopy, and micro-array technology, to time-resolved fluorescence and fluorescence depolarization imaging techniques. Analytical chemists and materials scientists will find this a useful addition to their armory. The contributors have sought to highlight the presen... |
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780,00 zł |
Alternative Splicing and Disease
ISBN: 9783642070815 / Angielski / Miękka / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. This is the first book to highlight the medical implications, i.e. diseases, caused by alternative splicing. Alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences. The book also outlines possible targets for therapy.
Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. This is the first book to highlight the medic... |
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780,00 zł |
Advanced Imaging in Biology and Medicine: Technology, Software Environments, Applications
ISBN: 9783642088537 / Angielski / Miękka / 445 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen s X-ray technology, were applied to the medical ?eld and while still crude revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional...
A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine ...
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cena:
780,00 zł |
Molecular Basis of Multiple Sclerosis: The Immune System
ISBN: 9783642141522 / Angielski / Twarda / 308 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. This book intents to review the advances made in this highly complex field.
Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclero...
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cena:
780,00 zł |
Handbook of Proteomic Methods
ISBN: 9781617375040 / Angielski / Miękka / 510 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A compendium of thirty-four powerful techniques for identifying and analyzing the diversity of proteins expressed in cells. Thee readily reproducible proteomic methods range from general to specific techniques, and include methods for data analysis, posttranslational modification, and its variants and isoforms. Additional methods demonstrate the application of proteomics to the discovery of serological tumor markers, to identifying the determinants of sensitivity to antitumor drugs, and to specialized fields, such as endocrinology, plant biology, nephrology, and urology.
A compendium of thirty-four powerful techniques for identifying and analyzing the diversity of proteins expressed in cells. Thee readily reproducible ...
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cena:
780,00 zł |
DNA Methylation, Epigenetics and Metastasis
ISBN: 9789048169177 / Angielski / Miękka / 310 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Most of the cancer patients die because the tumoral cells do not "stick" in the original site, but instead detach, invade and disseminate throughout the bloodstream to distal sites, where these transformed cells start to proliferate and destroy again. In the last ten years, researchers have identified a number of important genes involved in these processes, including cadherins, laminins, heparan sulfates, inhibitors of proteases and angiogenesis and many others. The puzzling problem was that few genetic alterations in these genes had been described in human tumors, despite the common finding...
Most of the cancer patients die because the tumoral cells do not "stick" in the original site, but instead detach, invade and disseminate throughout t...
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cena:
780,00 zł |
Programmed Cell Death in Cancer Progression and Therapy
ISBN: 9789048176687 / Angielski / Miękka / 356 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. With the discovery of key mechanisms that are involved in mediating PCD and in promoting resistance to therapy, design of therapeutic approaches for promoting tumor-selective cell death has risen dramatically. With this book, we give a comprehensive overview of the mechanisms that are involved in mediating and regulating PCD in cancer. We also provide a detailed indication of the utility of PCD in cancer therapy. This book will be a valuable resource for... Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. With the discov... |
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780,00 zł |
Heat Shock Proteins in Cancer
ISBN: 9789048176274 / Angielski / Miękka / 400 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point... Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance t... |
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780,00 zł |
Magnetic Resonance in Experimental and Clinical Oncology: Proceedings of the 21st Annual Detroit Cancer Symposium Detroit, Michigan, USA -- April 13 a
ISBN: 9780792309352 / Angielski / Twarda / 392 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past decade, techniques have been developed and implemented to observe metabolism noninvasively in localized regions of intact, living experimental animals and humans through the use of magnetic resonance spectroscopy (MRS). At the same time, magnetic resonance imaging (MRI) techniques developed in the 1970s and refined in this decade have been increasingly applied as a powerful clinical tool to probe human anatomy. Because of the unusual metabolic and physiologic characteristics of malignant tissues, oncology has been one of the primary focuses of the application of both MRS and...
Over the past decade, techniques have been developed and implemented to observe metabolism noninvasively in localized regions of intact, living experi...
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780,00 zł |
Multislice-CT of the Abdomen
ISBN: 9783642178627 / Angielski / Twarda / 365 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a lucid summary of modern multislice CT imaging of the abdomen, with a focus on the essential imaging findings. After a concise technical introduction, the most important abdominal diseases are described and illustrated with high-quality images. Sections are devoted to the liver and biliary system, the pancreas and spleen, the kidneys and urogenital system, and the bowel and peritoneal cavity. Throughout, key differential diagnostic features are highlighted. The editorial team is composed of internationally renowned radiologists from Europe and the United States, and all...
This book provides a lucid summary of modern multislice CT imaging of the abdomen, with a focus on the essential imaging findings. After a concise tec...
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cena:
780,00 zł |
Magnetic Resonance Imaging of the Bone Marrow
ISBN: 9783642178597 / Angielski / Twarda / 371 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book describes the MRI appearance of normal bone marrow, and the full range of bone marrow disorders, including malignancies and other conditions. Coverage includes the role of MRI in assessing treatment response, use of contrast media, and more.
This book describes the MRI appearance of normal bone marrow, and the full range of bone marrow disorders, including malignancies and other conditions...
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cena:
780,00 zł |
Neutron Capture Therapy: Principles and Applications
ISBN: 9783642313332 / Angielski / Twarda / 554 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle allows for tumor cell-selective high-LET particle radiotherapy. This book provides a comprehensive summary of the progress made in NCT in recent years. Individual sections cover all important aspects, including neutron sources, boron chemistry, drugs for NCT, dosimetry, and radiation biology. The use of NCT in a variety of malignancies and... Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probabilit... |
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cena:
780,00 zł |
Prostate Cancer: Biochemistry, Molecular Biology and Genetics
ISBN: 9781461468271 / Angielski / Twarda / 522 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Prostate Cancer provides an up-to-date review of the biochemistry, molecular biology, and genetic changes in prostate cells that are the driving forces in the initiation and progression of cancer. It includes an overview by experts in the field of cell-cell interactions, including stem cells, reactive Stromal cells and membrane lipid rafts that are instrumental in the initiation and progression of prostate cancer.
Prostate Cancer provides an up-to-date review of the biochemistry, molecular biology, and genetic changes in prostate cells that are the drivin...
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cena:
780,00 zł |
Natural Products in Cancer Prevention and Therapy
ISBN: 9783642345746 / Angielski / Twarda / 257 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Chemoprevention of Esophageal Squamous Cell Carcinoma with Berries, by Gary D. Stoner and Li-Shu Wang Cancer Prevention by Different Forms of Tocopherols, by Chung S. Yang and Nanjoo Suh Cancer Chemopreventive and Therapeutic Potential of Guggulsterone, by Inas Almazari and Young-Joon Surh Inhibition of UVB-Induced Nonmelanoma Skin Cancer: A Path from Tea to Caffeine to Exercise to Decreased Tissue Fat, by Allan H. Conney, You-Rong Lou, Paul Nghiem, Jamie J. Bernard, George C. Wagner and Yao-Ping Lu Cancer Chemoprevention and Nutri-Epigenetics: State of the Art and... Chemoprevention of Esophageal Squamous Cell Carcinoma with Berries, by Gary D. Stoner and Li-Shu Wang Cancer Prevention by Different Forms of... |
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780,00 zł |
Nuclear Analytical Methods in the Life Sciences
ISBN: 9781461267775 / Angielski / Miękka / 776 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer- encesheldbytheInternationalAtomicEnergyAgency. Thefirsttook placeinAmsterdamin 1967, thesecondin Bledin 1972, andthethird inViennain 1978. Theaimoftheseconferenceshasbeentostimulate discussions between scientists who are working as biologists, envi- ronmentalists, and physicians, and those who are working on the advancementofnuclear analytical techniques. The 1989 Conference was held at the National Institute of Standards and Technology (NIST, formerly the National Bureau of...
The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer- encesheldbytheInternationalAto...
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cena:
780,00 zł |
The P2 Nucleotide Receptors
ISBN: 9781461272892 / Angielski / Miękka / 440 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A state-of-the-art summary from leading laboratories around the world of our current knowledge of the molecular biology, the physiology, and the pharmacology of the P2 receptors. The authoritative contributions cover the major aspects of these receptors, describing the relationships between physiological and pharmacological effects of ATP and other nucleotides and the various cloned P2 receptors, as well as providing an historical perspective and discussing current issues of nomenclature. They also illuminate how P2 receptor structures contribute to their function, including the physical...
A state-of-the-art summary from leading laboratories around the world of our current knowledge of the molecular biology, the physiology, and the pharm...
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cena:
780,00 zł |