Recent Advances in Thrombosis and Hemostasis

ISBN-13: 9784431998518 / Angielski / Miękka / 2010 / 643 str.

K. Tanaka; E. W. Davie

Opis

Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hypertension, and obesity are the leading causes of morbidity and mortality. They have become urgent medical problems with serious economic consequences in industrialized and devel- ing countries alike. At the same time, the impact of molecular biology and genetics on our understanding of thrombosis and hemostasis is rapidly growing stronger as well as our knowledge of regeneration and development of specific tissues, organs, and embryos. Researchers are also constantly learning more about cardiovascular diseases as well as regulatory mechanisms for various intrinsic and extrinsic stimuli in viable tissues. In this volume, our intention has been to present the latest relevant information in molecular biology and genetics as well as the clinical implications of a better understanding of pathophysiology, novel diagnostic methodologies, and therapeutic applications for new methods of prevention in thrombosis/hemostasis and related disorders, including atherosclerosis. The dramatic advances in knowledge of thrombosis/hemostasis and vascular biology since the first publication of Recent Advances in Thrombosis and Fibrinolysis, edited with Japanese colleagues, in 1991, have required extensive revision in order to highlight and review recent progress in the field. The editors also gratefully welcome the seven distinguished non Japanese authors, who, with their valuable contributions on subjects beyond the coverage by Japanese authors, have made this new edition truly international.

Recenzje

Aus den Rezensionen: "Das Werk ... ist gekennzeichnet von großer fachlicher Kompetenz und wissenschaftlicher Erfahrung der Autoren und Herausgeber. Die Hämostaseologie wird aufgrund neuester Erfahrungen modern und spannend dargestellt. ... Die fachliche Kompetenz der Autoren durchzieht sämtliche Texte dieses herausragenden Werkes über Thrombose und Hämostase. Wegen seiner Aktualität sollte es in keiner Bibliothek eines interessierten Hämostaseologen fehlen. Wir wünschen dem Werk eine weite Verbreitung in allen Fachkreisen der Hämostaseologie." (H. D. Bruhn, in: Hämastaseologie, January/2010, Issue 1, S. 42)

Spis treści

Preface V Contributors XI Part 1 Coagulation Mechanism Part 2 Endothelial Cells and Inflammation Part 3 Platelets Part 4 Tissue Proteolysis Part 5 Vascular Development and Regeneration Part 6 Hemorrhagic Diathesis Part 7 Other Topics of Thrombosis and Hemostasis Part 8 Clinicals: Thrombosis-related Disorders and Recent Topics