Atomic Force Microscopy, Scanning Nearfield Optical Microscopy and Nanoscratching: Application to Rough and Natural Surfaces
ISBN: 9783642066634 / Angielski / Miękka / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Making a clear distinction is made between nano- and micro-mechanical testing for physical reasons, this monograph describes the basics and applications of the supermicroscopies AFM and SNOM, and of the nanomechanical testing on rough and technical natural surfaces in the submicron range down to a lateral resolution of a few nm. New or improved instrumentation, new physical laws and unforeseen new applications in all branches of natural sciences (around physics, chemistry, mineralogy, materials science, biology and medicine) and nanotechnology are covered as well as the sources for pitfalls...
Making a clear distinction is made between nano- and micro-mechanical testing for physical reasons, this monograph describes the basics and applicatio...
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cena:
776,43 zł |
Frontiers in Chemical Sensors: Novel Principles and Techniques
ISBN: 9783642066122 / Angielski / Miękka / 372 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With their similarity to the organs of the most advanced creatures that inhabit the Earth, sensors are regarded as being the "senses of electronics" arti?cial eyes and ears that are capable of seeing and hearing beyond the range of - man perception; electronic noses and tongues that can recognise odours and ?avours without a lifetime training; touch that is able not only to feel the texture and temperature of the materials but even to discern their chemical compo- tion. Among the world of chemical sensors, optical devices (sometimes termed "optodes," from the Greek "the optical way") have...
With their similarity to the organs of the most advanced creatures that inhabit the Earth, sensors are regarded as being the "senses of electronics" a...
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cena:
582,32 zł |
Topology in Molecular Biology
ISBN: 9783642062421 / Angielski / Miękka / 238 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The contents of this book focus on the recent investigations in molecular bi- ogywhereapplicationsoftopologyseemtobeverystimulating. Thevolumeis based on the talks and lectures given by participants of the three-month p- gram TopologyinCondensedMatter, whichwasheldintheMaxPlanck- stitut fur Physik komplexer Systeme, Dresden, Germany, 8May 31July 2002, under the scienti?c direction of Professors M. Kl eman, S. Novikov and - self. The aim of this program was to discuss recent applications of topology to several areas in condensed matter physics and molecular biology. The ?rst volume Topology in...
The contents of this book focus on the recent investigations in molecular bi- ogywhereapplicationsoftopologyseemtobeverystimulating. Thevolumeis based...
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cena:
582,32 zł |
The Genetics and Molecular Biology of Neural Tumors
ISBN: 9781617379376 / Angielski / Miękka / 450 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, The Genetics and Molecular Biology of Neural Tumors provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. Each chapter, with a comprehensive list of references and many informative tables, contains clinical and epidemiologic information, as well as succinct but relevant patho-histologic and immunohistochemical descriptions facilitating the interpretation of the findings on tumor genetics and... Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, The Genetic... |
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640,55 zł |
Biomarker Methods in Drug Discovery and Development
ISBN: 9781617379253 / Angielski / Miękka / 396 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The pharmaceutical industry has faced many significant challenges since the early 1990s. The fundamental issue that needs to be addressed is how to improve the efficiency of drug discovery and development. The current research and development (R&D) cost for developing a new therapeutic drug is greater than $800 million. Additionally, it takes an average of 12 years to get a new drug to market with an attrition rate greater than 90%. Reviewing the overall pharmaceutical R&D process, it has become clear that many of the drug failures are due to our lack of knowledge in population diversity,...
The pharmaceutical industry has faced many significant challenges since the early 1990s. The fundamental issue that needs to be addressed is how to im...
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582,32 zł |
Prenatal Diagnosis
ISBN: 9781617377877 / Angielski / Miękka / 331 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular biology has transformed prenatal diagnosis because it permits an accurate diagnosis to be made from very small quantities of fetal material, even single cells. Although the latter permits the analysis of preimplantation embryos and, perhaps in the future, the analysis of fetal cells enriched from maternal blood, a major current focus is to facilitate rapid, cost-effective diagnoses. In this manner, the use of fluorescence in situ hybridization (FISH) or polymerase chain reaction (PCR)-based approaches on uncultured amniocytes or chorionic villi already permits a rapid assessment of...
Molecular biology has transformed prenatal diagnosis because it permits an accurate diagnosis to be made from very small quantities of fetal material,...
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cena:
562,91 zł |
Mesenchymal Stem Cells: Methods and Protocols
ISBN: 9781617377679 / Angielski / Miękka / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic efficacy. In Mesenchymal Stem Cells: Methods and Protocols, leaders in the field were assembled to contribute detailed methodologies for the isolation and characterization of human and rodent MSCs. Recently, these vital cells have shown therapeutic benefits in the treatment of myocardial infarction, stroke, lung diseases, spinal cord injury and other neurological disorders, thus promising a boundless future in their study. Cutting edge and... For over forty years, mesenchymal stem cells (MSCs) have been scrutinized and studied, garnering much attention due to their broad therapeutic effi... |
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465,84 zł |
Innate Immunity
ISBN: 9781617377549 / Angielski / Miękka / 458 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains chapters dealing with the isolation and functional characterization of cells involved in innate immunity in mouse and man, including mast cells and eosinophils, and with several chapters focusing on natural killer cells. These approaches and models are being used to dissect the complex interplay between hosts and pathogens, and contribute to developing strategies to help fight infection.
This volume contains chapters dealing with the isolation and functional characterization of cells involved in innate immunity in mouse and man, inc... |
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582,32 zł |
Single Cell Diagnostics: Methods and Protocols
ISBN: 9781617376542 / Angielski / Miękka / 182 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Single Cell Diagnostics: Methods and Protocols applies modern Single Cell Diagnostics: Methods and Protocols applies modern |
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388,20 zł |
Oligonucleotide Synthesis: Methods and Applications
ISBN: 9781617374418 / Angielski / Miękka / 436 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of...
A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protoco...
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659,97 zł |
Interventional Radiology of the Spine: Image-Guided Pain Therapy
ISBN: 9781617374197 / Angielski / Miękka / 229 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A panel of world-renowned experts presents a complete course on evaluating and treating patients with back pain, including interventional spinal procedures, spinal imaging, and the clinical evaluation of the spine patient. The authors focus on all the critical spinal procedures, ranging from such traditional methods as selective nerve root blocks, epidural injections, facet injections, sacroiliac joint injections, to such state-of-the art techniques as spinal biopsy, percutaneous vertebroplasty, spinal imaging, nucleoplasty, discography, intradiscal electrothermal therapy, and transcatheter...
A panel of world-renowned experts presents a complete course on evaluating and treating patients with back pain, including interventional spinal proce...
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cena:
465,84 zł |
Death Receptors in Cancer Therapy
ISBN: 9781617374012 / Angielski / Miękka / 374 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling...
An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developin...
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427,02 zł |
Membrane Protein Protocols: Expression, Purification, and Characterization
ISBN: 9781617373763 / Angielski / Miękka / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment. Structural ana- sis of multiprotein complexes helps to define the role and interaction of each individual component, and can predict the...
Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientati...
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582,32 zł |
Protein Purification Protocols
ISBN: 9781617373343 / Angielski / Miękka / 484 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The first edition of Protein Purification Protocols (1996), edited by Professor Shawn Doonan, rapidly became very successful. Professor Doonan achieved his aims of p- ducing a list of protocols that were invaluable to newcomers in protein purification and of significant benefit to established practitioners. Each chapter was written by an ex- rienced expert in the field. In the intervening time, a number of advances have w- ranted a second edition. However, in attempting to encompass the recent developments in several areas, the intention has been to expand on the original format, retaining...
The first edition of Protein Purification Protocols (1996), edited by Professor Shawn Doonan, rapidly became very successful. Professor Doonan achieve...
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cena:
582,32 zł |
Fatty Acids: Physiological and Behavioral Functions
ISBN: 9781617372650 / Angielski / Miękka / 437 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leading academic and biomedical researchers comprehensively review the status of essential fatty acids (EFA) in nutrition, medicine, psychology, and pharmacology. Topics range from a discussion of EFA basic mechanisms to their effects on individual psychiatry and behavior, and include extensive coverage of pathology, DHA in CNS development, and phospholipid and fatty acid composition and metabolism. Comprehensive and forward-looking, Fatty Acids: Physiological and Behavioral Functions reviews and critically evaluates our current knowledge of EFA, setting the stage for oncoming wave of...
Leading academic and biomedical researchers comprehensively review the status of essential fatty acids (EFA) in nutrition, medicine, psychology, and p...
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cena:
854,08 zł |
Green Fluorescent Protein
ISBN: 9781617372469 / Angielski / Miękka / 394 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Could there be a better time to be a life scientist? In the past two decades, a host of new techniques have been added to the tool chests of biochemists and molecular biologists. A wonderful benefit of the basic scientific research that fueled the advances in these fields is the wide variety of direct applications in agriculture and medicine. Even with all of these advances, and with the accompanying explosion in computer and information technology, it is clear that the depth of our ignorance vastly exceeds the breadth of our knowledge about complex organisms at the molecular level. Any new...
Could there be a better time to be a life scientist? In the past two decades, a host of new techniques have been added to the tool chests of biochemis...
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388,20 zł |
Methods in Biological Oxidative Stress
ISBN: 9781617372001 / Angielski / Miękka / 216 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side-effects, xenobiotic toxicity, carcinogenesis, and the aging process, to name just a few. Because of the centrality of oxidative processes to normal and abnormal tissue function, it has become imperative to develop appropriate analytical techniques to facilitate the quantitation of significant reactants. Without advances in methodology, corresponding advances in our knowledge of underlying biochemical events will be necessarily limited. Drs....
Oxidative damage appears to play a central role in the development of a wide range of tissue pathology, including neurodegenerative disease, drug side...
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cena:
388,20 zł |
Recent Advances in Thrombosis and Hemostasis
ISBN: 9784431998518 / Angielski / Miękka / 643 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hypertension, and obesity are the leading causes of morbidity and mortality. They have become urgent medical problems with serious economic consequences in industrialized and devel- ing countries alike. At the same time, the impact of molecular biology and genetics on our understanding of thrombosis and hemostasis is rapidly growing stronger as well as our knowledge of regeneration and development of specific tissues, organs, and embryos....
Now more than ever, thrombotic and thromboembolic disorders as well as related diseases such as malignancies, arteriosclerosis, diabetes mellitus, hyp...
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cena:
776,43 zł |
New Frontiers in Lifestyle-Related Diseases
ISBN: 9784431998396 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is my great pleasure to publish New Frontiers in Lifestyle-Related Dis eases, the proceedings of the Showa University International Symposium for Life Sciences, 3rd Annual Meeting, held at Showa University on Sep tember 13, 2006. This symposium was supported, in part, by Grants for the Promotion of the Advancement of Education and Research in Graduate Schools and Ordinary Expenses for Private Schools from the Ministry of Education, Culture, Sports, Science, and Technology of Japan. On behalf of Showa University, I would like to express my deepest thanks to all the authors and editors for...
It is my great pleasure to publish New Frontiers in Lifestyle-Related Dis eases, the proceedings of the Showa University International Symposium for L...
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194,08 zł |
Visualizing Immunity
ISBN: 9783642101014 / Angielski / Miękka / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Understanding immune complexity in diverse tissue environments is a challenge for researchers. However, advances in imaging have greatly improved our ability to probe the immune system. This volume provides a synopsis of major insights in immunology revealed using imaging approaches.
Understanding immune complexity in diverse tissue environments is a challenge for researchers. However, advances in imaging have greatly improved our ...
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cena:
776,43 zł |