Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our com- protects against transforming defects in oncogenes prehension of the cellular and molecular pathology or tumor-suppressor genes and are here considered of malignant transformation is incomplete. In view as metasuppressor genes. Advances in the molecular of the diverse clinical presentations of various explanations of growth dysregulation, metastasis malignancies, doubts may be raised as to whether it formation, extension of life span, and...
Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our co...
This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signaling pathways to their roles in the clinical manifestation of specific cancers. Topics covered include molecular events intrinsic to tumor cells (leading to growth deregulation, extended lifespan, and the ability to invade surrounding tissue), protective mechanisms that prevent transformation (including DNA repair and epigenetic regulation), tumor-host interactions (with the endocrine system, the immune system, and blood vessel formation), and...
This book describes molecular processes whose deregulation is important in the formation of tumors. The material is developed from basic cell signa...
Molecular Therapies of Cancer sets out to comprehensively cover the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashion. While there is a huge literature on anti-cancer drugs, books on the subject are often concoctions of invited review articles with only superficial connections to each other. There is a lack of comprehensive and systematic text on the topic of molecular terapies in cancer. A further deficit in the relevant literature is a progressive sub-specialization that typically limits textbooks on cancer drugs to cover either pharmacology or medicinal...
Molecular Therapies of Cancer sets out to comprehensively cover the molecular mechanisms of anti-cancer drug actions in a comparably systematic fashio...
