Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug...

This book combines empirical research and theoretical discussions to demonstrate that the civil society paradigm as a western concept could be applicable to the study of state-society relations in contemporary China. However, the growth of Chinese civil society does not necessarily present an adversarial or confrontational relationship between state and society, but rather it is a cooperative relationship based on common interests and mutual benefits between industrial associations and local governments. The findings of this research confirm that, in contrast to the conventional civil society...