This volumes provides an overview of the most recent findings on the role of angiotensin and associated mediators in cardiovascular adaptation and disease, with a particular emphasis on the treatment of such diseases by ACE inhibitors.

An International Symposium "Catecholamines and the Heart" was held in Munich in May 1981, which was organized in cooperation with the Council on Cardiac Metabolism of the International Society and Federation of Cardiology and with the Microcirculation Working Group of the European Society of Cardiology. It was the aim of the organizers to evaluate in this Symposium the recent advances made in the field of sympathetic control of heart function. Particular attention was given to neural sympathetic pathways, to mechanisms and consequences of adrenoceptor stimulation and blockade as well as to...

This volume is the product of a symposium held on 14-16 February, 1985 in Ham- burg in honour of the 65th birthday of Prof. Hans-Joachim Schumann. Schumann was born on 28 December, 1919 in Stralsund. He studied medicine in Cologne, Greifswald and Rostock. The chair of pharmacology in Rostock was held at that time by Peter Holtz. It was he who first introduced Schumann to pharma- cology in 1944 and who was his Doktorvater (research supervisor). Mter the war, Schumann again worked with Holtz in Rostock and then in Frankfurt am Main. He received decisive stimuli during a research fellowship, in...

In den letzten Jahren haben Hemmstoffe des Konversionsenzyms bei der Indikation hoher Blutdruck, Herzinsuffizienz und bei Zustanden nach Myokardinfarkt eine Dif ferentialtherapie erlaubt, die in ihren Ergebnissen bemerkenswert ist und uber eine Organ protektion zur Senkung der Mortalitat dieser letalen kardiovaskularen Erkrankungen beigetragen haben. Experimentelle Untersuchungen haben die Bedeutung der organstandigen Renin-Angiotensin-Systeme hervorgehoben und neue Aussichten zur Behandlung der Hypertrophie des Herzens und der Arteriosklerose der Gefasse eroffnet. Im hier vorliegenden Band,...