A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by which the brain acts as an endocrine organ, not only to control hormonal functions, but also to maintain homeostasis and regulate behavior. The authors-recognized both as leaders in their fields and as skilled teachers-provide systematic coverage of the analytical, anatomical, functional, clinical, and pathological aspects of neuroendocrinology. Topics range from the interactions between the nervous and endocrine systems to the regulation of...
A panel of leading experts integrate the latest findings from basic and clinical science to create a comprehensive treatment of the processes by whic...
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation
The authors explain how these methods are able to provide important biological...
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approache...
We are now on the verge of viewing effector molecules and other regulatory sites as therapeutic targets for the amelioration of human and animal disease. The recognition, for example, that mutant proteins are frequently misrouted molecules, rather than functionally defective ones, changes our approach to "inborn errors of metabolism" and offers new approaches for pharmacological discovery, based on rescue of receptors, ion channels and enzymes with pharmacoperones. Ion channels, regulators of G-protein signaling and enzymes engaged in regulation, now present opportunities for drug...
We are now on the verge of viewing effector molecules and other regulatory sites as therapeutic targets for the amelioration of human and animal di...
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation
The authors explain how these methods are able to provide important biological...
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approache...
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation
The authors explain how these methods are able to provide important biological...
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approache...
THE STATE oF HoRMONE AcTioN levels were induced in concert with ligand occupa- tion of certain membrane receptors and this second AND MoLECULAR REGULATION messenger (cAMP) was postulated to initiate intra- cellular phosphorylation of unknown targets. At Molecular Endocrinology and Regulation is a this point, the field ofPeptide Hormone Action also burgeoning field, having experienced a remarkable came into being. period of growth since the late 1960s. At that time, These fields developed together for much ofthe there was no field of Hormone Action. The prevail- next decade. Hormone Action...
THE STATE oF HoRMONE AcTioN levels were induced in concert with ligand occupa- tion of certain membrane receptors and this second AND MoLECULAR REGULA...
A compendium of thirty-four powerful techniques for identifying and analyzing the diversity of proteins expressed in cells. Thee readily reproducible proteomic methods range from general to specific techniques, and include methods for data analysis, posttranslational modification, and its variants and isoforms. Additional methods demonstrate the application of proteomics to the discovery of serological tumor markers, to identifying the determinants of sensitivity to antitumor drugs, and to specialized fields, such as endocrinology, plant biology, nephrology, and urology.
A compendium of thirty-four powerful techniques for identifying and analyzing the diversity of proteins expressed in cells. Thee readily reproducible ...
This volume of Methods in Enzymology is the first of three parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
Expert authors who are leaders in the field
Extensively referenced and useful figures and tables
Provides hints and tricks to facilitate reproduction of methods
This volume of Methods in Enzymology is the first of three parts looking at current methodology for the imaging and spectroscopic analysis o...
This volume of Methods in Enzymology is the second of three parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
Expert authors who are leaders in the field
Extensively referenced and useful figures and tables
Provides hints and tricks to facilitate reproduction of methods
This volume of Methods in Enzymology is the second of three parts looking at current methodology for the imaging and spectroscopic analysis ...
This volume of Methods in Enzymology is the third of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
The third of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells
The chapters provide hints and tricks not available in primary research publications
It is an invaluable resource for academics, researchers...
This volume of Methods in Enzymology is the third of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cell...