"Lysosomes are now known tobe notjustacollectionofisolatedorganellesofin- terest only to the biochemist, but part ofa complex, dynamic, membranous sys- tem essential to the cell's economy." So wrote the late Dame Honor Fell and I in the preface to the first volume of Lysosomes in Biology and Pathology almost 30 years ago. We wentonto say thatresearchonthelysosomalsystematthetimewas in a state ofexplosive and chaotic growth. While the chaos has beenlargely reduced, the growthofresearch into the bi- ology ofthe lysosome remains considerable. Biologists worldwide are still fasci- nated by the...
"Lysosomes are now known tobe notjustacollectionofisolatedorganellesofin- terest only to the biochemist, but part ofa complex, dynamic, membranous sys...
Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is formed in an initial step of lipid peroxidation. Lipid hydroperoxide is also known as a potential source of singlet oxygen. Harmful aldehydes are formed when the lipid hydroperoxide is degraded. The formed aldehyde has high reactivity against thiol or amine moieties. Therefore, it could act as a signaling molecule, which might induce the changing of gears inside a cell. Recent studies have shown that lipid hydroperoxide or a slightly modified...
Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is f...
This comprehensive, edited book explores carotenoids and their important functional roles in yeast, bacteria and plants and a profound exposition on the structures of carotenoid molecules, focusing in the first of three parts on the biosynthesis of carotenoids.
This comprehensive, edited book explores carotenoids and their important functional roles in yeast, bacteria and plants and a profound exposition on t...
As stated by its first editor, Dr. D. B. Roodyn, the primary goal of the series Subcellular Biochemistry is to achieve an integrated view of the cell by bringing together results from a wide range of different techniques and disciplines. This volume deals with the applications of fluorescence spectroscopy to membrane research. It seeks to present complementary biochemical and bio physical data on both the structure and the dynamics of biological membranes. Biophysics and biochemistry are improving more and more in their ability to study biomembranes, overlapping somewhat in this area and...
As stated by its first editor, Dr. D. B. Roodyn, the primary goal of the series Subcellular Biochemistry is to achieve an integrated view of the cell ...
Volume 18 of the Subcellular Biochemistry series, which specializes in various aspects of the biochemistry of the intracellular parasites, was initially proposed by Jose Luis Avila and strongly supported by myself, as Series Editor of Sub- cellular Biochemistry. Considerable assistance was received from Professor Frank Wunderlich (University of Dusseldorf) and more particularly from Dr. Michael Miles (London School of Hygiene and Tropical Medicine) during the compilation of the list of possible chapters. Our initial aim was to present a comprehensive survey of this broad field of study....
Volume 18 of the Subcellular Biochemistry series, which specializes in various aspects of the biochemistry of the intracellular parasites, was initial...
Cellular virology has made tremendous advances in the past decade due to the availability and application of new immunological techniques together with the vast range of biochemical techniques and the continued impact of transmission electron microscopy. The chapters contained in this volume provide significant coverage of the subject of cellular virology as a whole. Considerable overall emphasis is placed upon the membrane biochemistry of viral proteins and glycoproteins within the infected cell. In the opening chapter Edouard Kurstak and his colleagues provide a useful survey on the...
Cellular virology has made tremendous advances in the past decade due to the availability and application of new immunological techniques together wit...
This volume and future ones in the series, which is now under new editorship. depart from the pattern established by previous volumes in containing chapters loosely related to one another. It is thus appropriate that each volume should have a relevant subtitle. In the present volume the underlying theme is immu- nology and its application to the study of a number of different biochemical systems. Almost inevitably, the study of the cell-surface antigens and glycoproteins of a number of different tissues tends to dominate the contents, but considerable emphasis is also placed on subcellular...
This volume and future ones in the series, which is now under new editorship. depart from the pattern established by previous volumes in containing ch...
This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of...
This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fiel...
The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. The number of publications on the topic has increased from nothing in the early 1980s to more than 10,000 papers annually today. It is now well recognized that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The idea that life requires death seems somewhat paradoxical, but cell suicide is essential for an animal to survive. For example, without selective destruction of "non-self" T...
The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. T...
The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, derived from "vital-amines," indicates their elementary metabolic key functions in human metabolism. Vitamins are truly families of compounds, which include precursors and various free and bound forms, all with individual roles in metabolism and function. A more recent approach therefore searches for the components, the understanding of...
The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequen...
