This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is currently facing and for enhancing LDI efficiency. It presents a variety of cutting-edge nanophotonic structures to satisfy the mass-analytical needs of sensitivity, reproducibility, and quantification. As opposed to the commercialized, conventional organic matrix used in MALDI-MS, these nanostructures are validated to be highly effective in detecting small metabolites and drugs,...
This book presents innovative laser desorption ionization (LDI)-active nanophotonic structures for addressing the challenges that matrix-assisted lase...
This thesis proposes useful tools, on-the-fly trajectory mapping method and Reaction Space Projector (ReSPer), to analyze chemical reaction mechanisms by combining the reaction route map and the ab initio molecular dynamics. The key concept for the proposed tools is the Cartesian distance between pairwise molecular structures, and a practical procedure to get the optimal distance is introduced. The on-the-fly trajectory mapping method tracks the distance function between reference structures and molecular structures along the trajectory. Although this method provides fruitful insight into...
This thesis proposes useful tools, on-the-fly trajectory mapping method and Reaction Space Projector (ReSPer), to analyze chemical reaction mechanisms...
This book deals with efficient estimation and optimization methods to improve the design of electrotechnical devices under uncertainty. Uncertainties caused by manufacturing imperfections, natural material variations, or unpredictable environmental influences, may lead, in turn, to deviations in operation. This book describes two novel methods for yield (or failure probability) estimation. Both are hybrid methods that combine the accuracy of Monte Carlo with the efficiency of surrogate models. The SC-Hybrid approach uses stochastic collocation and adjoint error indicators. The...
This book deals with efficient estimation and optimization methods to improve the design of electrotechnical devices under uncertainty. Uncert...
This book reports on a set of advances relating to nonlinear observer design, with a special emphasis on high-gain observers. First, it covers the design of filters and their addition to the observer for reducing noise, a topic that has been so far neglected in the literature. Further, it describes the adaptive re-design of nonlinear observers to reduce the effect of parametric uncertainty. It discusses several limitations of classical methods, presenting a set of successfull solutions, which are mathematically formalised through Lyapunov stability analysis, and in turn validated via...
This book reports on a set of advances relating to nonlinear observer design, with a special emphasis on high-gain observers. First, it covers the des...
This book focuses on the development of novel functionalized organoboron compounds and those synthetic methods. High degrees of chemo-, regio-, and stereoselectivities of the borylation reactions are attained through catalyst design and optimization. Furthermore, the selectivity-determining mechanisms are analyzed with state-of-the-art DFT and other computational methods.
In this book, the author synthesizes some multi-substituted alkenyl and allylic boronates via borylation reactions using a copper(I)/diboron catalyst system. Those compounds contain novel densely substituted and...
This book focuses on the development of novel functionalized organoboron compounds and those synthetic methods. High degrees of chemo-, regio-, and...
Precision measurements of the Higgs boson’s properties are a powerful tool to look for deviations from the predictions of the Standard Model (SM) of particle physics. The 139/fb of proton-proton collision data which have been collected by the ATLAS experiment during Run 2 of the LHC, offer an opportunity to investigate rare Higgs-boson topologies, which are particularly sensitive to new physics scenarios but experimentally difficult to access. Several such measurements, which target Higgs-boson decays to heavy-flavour quarks, as well as their combinations are presented in this thesis. A...
Precision measurements of the Higgs boson’s properties are a powerful tool to look for deviations from the predictions of the Standard Model (SM) of...
This book explores the Higgs boson and its interactions with fermions, as well as the detector technologies used to measure it. The Standard Model of Particle Physics has been a groundbreaking theory in our understanding of the fundamental properties of the universe, but it is incomplete, and there are significant hints which require new physics. The discovery of the Higgs boson in 2012 was a substantial confirmation of the Standard Model, but many of its decay modes remain elusive. This book presents the latest search for Higgs boson decays into c-quarks using a proton-proton collision...
This book explores the Higgs boson and its interactions with fermions, as well as the detector technologies used to measure it. The Standard Model of ...
Since the initial predictions for the existence of Weyl fermions in condensed matter, many different experimental techniques have confirmed the existence of Weyl semimetals. Among these techniques, optical responses have shown a variety of effects associated with the existence of Weyl fermions. In chiral crystals, we find a new type of fermions protected by crystal symmetries — the chiral multifold fermions — that can be understood as a higher-spin generalization of Weyl fermions.
This work provides a complete description of all chiral multifold fermions, studying their...
Since the initial predictions for the existence of Weyl fermions in condensed matter, many different experimental techniques have confirmed the exi...
This book focuses on the development of novel functionalized organoboron compounds and those synthetic methods. High degrees of chemo-, regio-, and stereoselectivities of the borylation reactions are attained through catalyst design and optimization. Furthermore, the selectivity-determining mechanisms are analyzed with state-of-the-art DFT and other computational methods.
In this book, the author synthesizes some multi-substituted alkenyl and allylic boronates via borylation reactions using a copper(I)/diboron catalyst system. Those compounds contain novel densely substituted and...
This book focuses on the development of novel functionalized organoboron compounds and those synthetic methods. High degrees of chemo-, regio-, and...
This book investigates the physics of the discovered Higgs boson and additional Higgs bosons in the extended Higgs models which includes higher-order quantum corrections. While the 125 GeV Higgs boson was discovered, the structure of the Higgs sector is still a mystery. Since the Higgs sector determines the concrete realization of the Higgs mechanism, the study of its nature is one of the central interests in current and future high-energy physics.
The book begins with a review of the standard model and the two-Higgs doublet model, which is one of the representatives of the...
This book investigates the physics of the discovered Higgs boson and additional Higgs bosons in the extended Higgs models which includes higher-ord...