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Millions of people complain of sleep problems, from insomnia to excessive daytime sleepiness, to chronic fatigue and the irritability associated with unsatisfactory sleep. Sleep problems are an important aspect of several psychiatric disorders, notably mood and anxiety disorders. Sleep deprivation has also been identified as a factor in numerous other medical conditions, including diabetes and impaired immune function. No matter what its specific medical source, sleep deprivation possesses high societal costs-impaired driving, work-related accidents and chronically poor work performance. In...

This book reviews current knowledge on the importance of sleep for brain function, from molecular mechanisms to behavioral output, with special emphasis on the question of how sleep and sleep loss ultimately affect cognition and mood.

This book reviews current knowledge on the importance of sleep for brain function, from molecular mechanisms to behavioral output, with special emphasis on the question how sleep and sleep loss ultimately affect cognition and mood. It provides an extensive overview of the latest insights in the role of sleep in regulating gene expression, synaptic plasticity and neurogenesis and how that in turn is linked to learning and memory processes. In addition, readers will learn about the potential clinical implications of insufficient sleep and discover how chronically restricted or disrupted sleep...