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This volume of Springer's Handbook of Experimental Pharmacology explores the wide range of factors relating to sodium channels, from their biophysical behavior, structure, and pathological vulnerabilities to the methodologies employed in studying them.

A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into...

The meal-in-a-bowl brews at the Daily Soup, a Manhattan food chain, excite customer devotion. Now Leslie Kaul, the stores' executive chef, along with the owners, offer The Daily Soup Cookbook, a collection of 200 favorite recipes for soups, stews, and stocks. These straightforward formulas, drawn from a globe-spanning repertoire, will please cooks of all kinds, from beginners to the accomplished.
Organized by ingredients such as vegetables, beans, grains, and fruit, the recipes include old favorites like French Onion and Chicken Matzoh Ball soups, as well as less familiar brews...

The great mathematician G. H. Hardy told us that "Beauty is the ?rst test: there is no permanent place in the world for ugly mathematics" (see 24, p. 85]). It is clear why Hardy loved complex analysis: it is a very beautiful partofclassicalmathematics. ThetheoryofHilbertspacesandofoperatorson themisalmostasclassicalandisperhapsasbeautifulascomplexanalysis. The studyoftheHardy-Hilbertspace(aHilbertspacewhoseelementsareanalytic functions), and of operators on that space, combines these two subjects. The interplay produces a number of extraordinarily elegant results. For example, very...

The great mathematician G. H. Hardy told us that "Beauty is the ?rst test: there is no permanent place in the world for ugly mathematics" (see 24, p. 85]). It is clear why Hardy loved complex analysis: it is a very beautiful partofclassicalmathematics. ThetheoryofHilbertspacesandofoperatorson themisalmostasclassicalandisperhapsasbeautifulascomplexanalysis. The studyoftheHardy-Hilbertspace(aHilbertspacewhoseelementsareanalytic functions), and of operators on that space, combines these two subjects. The interplay produces a number of extraordinarily elegant results. For example, very...