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Presented is a new computer-aided multispectral image processing method which is used in 3 spatial dimensions and 1 spectral dimension where the dynamic, contrast enhanced magnetic resonance parameter maps derived from voxelwise model-fitting represent the spectral dimension. The method is based on co-occurrence analysis using a 3-dimensional window of observation which introduces an automated identification of suspicious lesions. The co-occurrence analysis defines 21 different statistical features, a subset of which were input to a neural network classifier where the assessments of the...