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The Beta-3 Adrenoreceptor plays an important role in regulating human fat storage and variants of this receptor are thought to be relevant to diabetes.
In addition to the major interest in obesity and diabetes expressed by the pharmaceutical industry, increasing numbers of academic groups are attracted by this general research area. This renewed interest is of course in part stimulated by available financing from industry. It also reflects the growing realisation that metabolism remains an open frontier: little is known about adipocyte sub-populations, specific markers, or endocrine...

As America's struggle with the dual problem of exploding health costs and assuring access to health care for the uninsured, health care rationing has moved to the centre of the public policy debate. A prime example of this is the intense public discussion surrounding the proposal by the state of Oregon to provide universal health care but to ration which diagnoses and treatments will be covered. Focusing largely on the Oregon proposal, this volume examines a wide range of ethical, methodological, legal and political issues that must be addressed by any serious programme of health care...

Can medical ethics be legislated? Can a complex bioethical question be definitively answered through legislation? In July 1987 the New York State legislature experimented with legislating medical ethics by amending the state's public health law to regulate Do Not Resuscitate' orders. The consequent law was complex and remains controversial. This volume reviews both the background bioethical debates and the elements of the public policy making process that are essential to understanding New York's experience with the DNR law. It features debates between leading exponents and critics of the...

"The Advances in Bioethics" series is devoted to publishing collections of original papers and multi-authored volumes that advance the field of bioethics either by exploring new areas, or by taking new approaches to traditional areas. Although the series is published in English, its scope is international, and manuscripts are welcome from authors throughout the world. Divided into three sections this volume covers: Human Rights, Public Safety, and Public Policy; Practitioner Responsibilities During Times of Epidemics; Global Dimensions of Epidemics - each chapter in the book goes in depth to...