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In recent years a breakthrough has occurred in our ability to draw inferences from exact and optimum tests of variance component models, generating much research activity that relies on linear models with mixed and random effects. This volume covers the most important research of the past decade as well as the latest developments in hypothesis testing. It compiles all currently available results in the area of exact and optimum tests for variance component models and offers the only comprehensive treatment for...

This book constitutes the thoroughly refereed proceedings of the Second International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2011, held in Toulouse, France, in August/September 2011, in conjunction with DEXA 2011.

The 13 long papers and 5 short papers were carefully selected and address the following topics: decision support and data management in biomedicine; medical data mining and information retrieval; workflow management and decision support in medicine; and classification in bioinformatics. The papers show how broad the spectrum of topics in...