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Biomedical engineering and medical informatics are challenging and rapidly growing areas. Applications of information technology in these areas are of paramount imp- tance. The aim of the first ITBAM conference was to bring together scientists, - searchers and practitioners from different disciplines (mathematics, bioinformatics, biology, medicine, biomedical engineering and computer science) having such c- mon interests. We hope that ITBAM conferences will provide opportunities for fru- ful discussions between all attendees and provide a platform where participants can exchange their most...

This book constitutes the refereed proceedings of the 4th International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2013, held in Prague, Czech Republic, in August 2013, held in conjunction with DEXA 2013. The 7 revised long papers presented together with 4 short papers were carefully reviewed and selected from numerous submissions. The papers address the following topics: critical health and intelligent systems in medical research, and obstetrics, neonatology and decision systems in cardiology.