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Endodontic microsurgery, is a specialized dental procedure that uses a microscope for precise treatment of persistent or recurrent root canal infections. It involves making a small incision near the tooth, removing infected or damaged tissue, and repairing or resecting the root tip as needed. The use of a microscope provides enhanced visualization and accuracy, resulting in faster healing times and improved outcomes. Endodontic microsurgery is recommended when conventional root canal treatment has failed or when other treatment options are not feasible. It offers numerous benefits and is a...

Carvedilol has unique pharmacological profile. It blocks 1, 2, and 1 receptors, used in the management of hypertension and as an adjunct to standard therapy in symptomatic heart failure and also produces vasodilation. In the present study, an attempt has been made to improve drug concentration in the stomach by preparing gastroretentive floating microsphere of carvedilol phosphate to maintain drug levels within a desired range, reduce dosing frequency, Improve patient compliance, improve dissolution and at the site of absorption.Drug molecules presenting no difficulties in their solubility...