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From a public health point of view, there is little doubt that one of the most important preventable causes of disease worldwide is tobacco smoking. It is also clear that tobacco smoke contains a vast number of chemicals with important biological efects in disease processes. Te gas phase of tobacco smoke is oxidizing, the tar phase is reducing, and whole smoke is roughly neutral, so its efects on oxidative stress may be an antioxidant paradox. From a scientifc point of view, we found it of interest to make a comprehensive ov- view of what we presently know about oxidative stress and tobacco...

From a public health point of view, there is little doubt that one of the most important preventable causes of disease worldwide is tobacco smoking. It is also clear that tobacco smoke contains a vast number of chemicals with important biological efects in disease processes. Te gas phase of tobacco smoke is oxidizing, the tar phase is reducing, and whole smoke is roughly neutral, so its efects on oxidative stress may be an antioxidant paradox. From a scientifc point of view, we found it of interest to make a comprehensive ov- view of what we presently know about oxidative stress and tobacco...