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This title encompasses over 30 years of progress towards our understanding of calcium channel structure, function, regulation, physiology, pharmacology, and genetics. It balances contributions from many of the leading authorities in the calcium channel field with fresh perspectives from risings stars in the area.

This book covers the tremendous progress in the current understanding of the molecular physiology of voltage-gated calcium channels. This book includes unparalleled insights into structural features of calcium channels due to X-ray crystallography and cryo-EM, which in turn yielded critical information into how these channels function under normal and pathophysiological conditions, and how they interact with calcium channel therapeutics. The chapters investigate how, with the advent of high throughput genome sequencing, numerous mutations in various calcium channel genes have been identified...