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In Casting for Big Ideas, Andrew Jaffe, industry veteran and Director of the Clio Awards, details important lessons on the management and growth of advertising agencies. He shows how the forty-year-old agency business model is breaking down because the work is becoming marginalized, as clients cut back ad budgets and hire outside marketing services and strategy firms. If agencies are to survive, Jaffe says, they must become idea-focused again and, instead of just making ads, master the art of devising the kind of non-advertising-type promotions that more quickly move a brand into the culture....

Covering a subject of burgeoning interest, this reference studies the most recent advances in the development of ocular drug delivery systems and offers new and expanded chapters on animal models for pharmacokinetic studies, gene therapy in the eye, and microparticulates for ocular drug delivery. Covering methods to treat or prevent ocular inflammation and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, and diabetic macular edema.

In recent years cosmologists have advanced from largely qualitative models of the Universe to precision modelling using Bayesian methods, in order to determine the properties of the Universe to high accuracy. This timely book is the only comprehensive introduction to the use of Bayesian methods in cosmological studies, and is an essential reference for graduate students and researchers in cosmology, astrophysics and applied statistics. The first part of the book focuses on methodology, setting the basic foundations and giving a detailed description of techniques. It covers topics including...