Intraocular Drug Delivery

ISBN-13: 9780824728601 / Angielski / Twarda / 2006 / 384 str.

Glenn J. Jaffe; Captain Paul Ashton; P. Andrew Pearson

Opis

Covering a subject of burgeoning interest, this reference studies the most recent advances in the development of ocular drug delivery systems and offers new and expanded chapters on animal models for pharmacokinetic studies, gene therapy in the eye, and microparticulates for ocular drug delivery. Covering methods to treat or prevent ocular inflammation and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, and diabetic macular edema.

Spis treści

GENERAL. Retinal Drug Delivery. Blood Retinal Barrier. Neuroprotection. Regulatory Issues in Drug Delivery to the Eye. SPECIFIC DELIVERY SYSTEMS. Intravitreal Injection. Anti-angiogenic Agents. Intravitreal Antimicrobials. Pharmacologic Retinal Reattachment with INS37217 (Denufosol Tetrasodium), a Nucleotide P2Y2 Receptor Agonist. Cell Based Delivery Systems. Photodynamic Therapy. Thermal Sensitive Liposomes. Gene Therapy for Retinal Disease. Biodegradable Systems. Transscleral Drug Delivery to the Retina and Choroid. Nondegradable Intraocular Sustained Release Drug Delivery Devices. LOCAL DRUG DELIVERY APPROACH TO SPECIFIC CLINICAL DISEASES. Age-Related Macular Degeneration. Photodynamic Therapy Human Clinical Studies. Age-Related Macular Degeneration Drug Delivery. Intraocular Sustained Drug Delivery in Uveitis. Drug Delivery for Proliferative Vitreoretinopathy: Prevention and Treatment. Pharmacological Treatment in Diabetic Macular Edema. Retinal Vein Occlusion. Cytomegalovirus (CMV) Retinitis. Endophthalmitis

O autorze

Glenn J. Jaffe

Paul Ashton 

P. Andrew Pearson