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A series of novel alpha-beta chimeric oligodeoxynucleotides bearing either an intercalator-conjugated nucleobase located at the internal 4-nt linker region or an anthraquinone-conjugated propionic acid as a non-nucleosidic backbone unit at the internal linker region was synthesized. The UV-melting experiments reveled that the obtained modified chimera TFOs formed remarkably stable alternate-stranded triplex. On the other hand, modified TFOs bearing non-nucleosidic intercalator-conjugate possessed two diastereomers formed substantially stable alternate-stranded triple helix almost regardless...

The crude methanolic extract and different fractions of the whole plant of Gomphrena globosa(L) were subjected to phytochemical screening.The whole plant of G. globosa was extracted with methanol by cold extraction.From the concentrated methanolic crude extract Stigmasterol, beta Sitosterol and Isochavicinic acid were isolated with the help of different standard separating techniques.The isolated compounds were characterized by 1HNMR data and compared with authentic published data.Herewith Isochavicinic acid was isolated and characterized by 1HNMR and 2DNMR data for the first time from this...