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The purpose of the present study was to evaluate the neuropharmacological, analgesic, antidiarrheal and antimicrobial activity of methanolic crude extract of Ziziphus mauritiana leaves in mice model. Among all the fractions, methanolic extract at a dose of 200 and 400 mg/kg body weight revealed 27.6 and 29.6 minutes of onset of sleeping; 79 and 89.8 minutes of total sleeping time where control group showed 15.8 minutes of onset of sleeping and 118.6 minutes of total sleeping time. Besides crude extract at a dose of 400 mg/kg body weight significantly inhibited the pain sensation at 48.55%,...

The four synthetic compounds named Ortho-amino aniline, 2-bromo propyl amine hydrobromide, 3-bromopopyl ammonium bromide and Benzimidazole-2-thiol were evaluated for their pharmacological activity. Evaluation of anti-oxidant activity was done by DPPH free radical scavenging activity. In this investigation, the compound ortho amino aniline showed the highest free radical scavenging activity with IC50 value 0.85 g/ml. At the same time Benzimadazole-2-Thiol also showed strong antioxidant potential having IC50 value 4.18 g/ml. The cyto-toxic activity was evaluated using Brine shrimp lethality...

The crude methanolic extract and different fractions of the whole plant of Gomphrena globosa(L) were subjected to phytochemical screening.The whole plant of G. globosa was extracted with methanol by cold extraction.From the concentrated methanolic crude extract Stigmasterol, beta Sitosterol and Isochavicinic acid were isolated with the help of different standard separating techniques.The isolated compounds were characterized by 1HNMR data and compared with authentic published data.Herewith Isochavicinic acid was isolated and characterized by 1HNMR and 2DNMR data for the first time from this...