The Chemistry of β-Lactams

ISBN-13: 9789401053006 / Angielski / Miękka / 2012 / 351 str.

M. I. Page

Opis

This book provides an authoritative review of developments in the chemistry of Beta-lactams: in particular the synthesis, reactivity and mechanisms of reaction, including novel Beta-lactam structures and non-Beta-lactam analogues.

Spis treści

The biosynthesis of Beta-lactums. Structure-activity relationships: Chemical. Structure-activity relationships: biological. The mechanisms of reactions of Beta-lactams. Mode of action: interaction with the penicillin binding proteins. Beta-Lactamase: mechanism of action. Beta-Lactamase: inhibition. Novel Beta-Lactam structures-the carbacephems . Non-Beta-Lactam mimics of Beta-lactam antibiotics. Classical Beta-Lactam structures. Index.