The Biological Chemistry of Nickel

ISBN-13: 9781782624981 / Angielski / Twarda / 2017 / 380 str.

Deborah Zamble; Jennifer Glass; Henryk Kozlowski

Opis

Nickel is an essential element in many biochemical processes and there has been significant research into understanding in great depth the role thatthis transition element plays. This book provides a comprehensive review of the latest findings in nickel biology, covering the function, biochemistry, toxicology and medical applications of nickel systems. Chapters discuss a range of topics in this field including the coordination chemistry of nickel-containing biomolecules, current theories on nickel-containing enzymes and the transport, storage and transcriptional regulation of nickel in biological systems. Issues such as the key role of nickel in pathogens, nickel toxicity in humans and the potential medical applications are also examined. Written by internationally leading experts in nickel biology and chemistry research, this book is an essential reference for bioinorganic chemists, biochemists, biologists and medicinal chemists."