Ruthenium and Other Non-Platinum Metal Complexes in Cancer Chemotherapy

ISBN-13: 9783642747625 / Angielski / Miękka / 2011 / 226 str.

Opis

Contents/Information: N.P. Johnson, J.-L. Butour, G. Villani, F.L. Wimmer, M. Defais, V. Pierson, Toulouse, France; V. Brabec, Kralovopolska, CSSR: "Metal Antitumor " "Compounds: The Mechanism of Action of Platinum Complexes " "Pertaining to the Design of Anticancer Agents"B.K. Keppler, M. Henn, U.M. Juhl, M.R. Berger, R. Niebl, Heidelberg; F.E. Wagner, Garching, FRG: "New Ruthenium Complexes for the " "Treatment of Cancer"G. Mestroni, E. Alessio, Trieste, M. Calligaris, Pavia, Italy; W.M. Attia, Ismailia, Egypt; F. Quadrifoglio, S. Cauci, Udine, Italy; G. Sava, S. Zorzet, S. Pacor, C. Monti-Bragadin, M. Tamaro, L. Dolzani, Trieste, Italy: "Chemical, Biological and Antitumor Properties of " "Ruthenium (II) Complexes with Dimethylsulfoxide"N. Farrell, Burlington/VT, USA: "Metal Complexes as Radiosensitizers"S.C. Srivastava, L.F. Mausner, M.J. Clarke, Upton/NY, and Chestnut Hill/MA, USA: "Radioruthenium-Labeled Compounds for " "Diagnostic Tumor Imaging"P. Kopf-Maier, Berlin, FRG: "The " "Antitumor Activity of Transition and Main-Group Metal " "Cyclopentadienyl Complexes"E.V. Scott, G. Zon, L.G. Marzilli, Atlanta/GA and Foster City/CA, USA: "NMR Relaxation " "Footprinting: The ACr(NH3)6U3+ Cation as a Probe for Drug " "Binding Sites on Oligonucleotides"J.E. Schurig, H.A. Meinema, K. Timmer, Wallingford/CT, USA; B.H. Long, A.M. Casazza, Zeist, NL: "Antitumor Activity of " "BisABis(Diphenylphosphino)Alkane and AlkeneU Group VIII " "Metal Complexes"M.E. Heim, H. Flechtner, Mannheim; B.K. Keppler, Heidelberg, FRG: "Clinical Studies with Budotitane -" "A New Non-Platinum Metal Complex for Cancer Therapy""

Spis treści

Metal Antitumor Compounds: The Mechanism of Action of Platinum Complexes.- Ruthenium Chemistry Pertaining to the Design of Anticancer Agents.- New Ruthenium Complexes for the Treatment of Cancer.- Chemical, Biological and Antitumor Properties of Ruthenium(II) Complexes with Dimethylsulfoxide.- Metal Complexes as Radiosensitizers.- Radioruthenium-Labeled Compounds for Diagnostic Tumor Imaging.- The Antitumor Activity of Transition and Main-Group Metal Cyclopentadienyl Complexes.- NMR Relaxation Footprinting: The [Cr(NH3)6]3+ Cation as a Probe for Drug Binding Sites on Oligonucleotides.- Antitumor Activity of Bis[Bis(Diphenylphosphino)Alkane and Alkene] Group VIII Metal Complexes.- Clinical Studies with Budotitane — A New Non-Platinum Metal Complex for Cancer Therapy.- Author Index Volumes 1–10.