Oxidative Stress, Inflammation, and Health

ISBN-13: 9780824727338 / Angielski / Twarda / 2005 / 636 str.

Young-Joon Surh; Lester Packer

Opis

Specifically focusing on the redox regulation of cell signaling responsible for oxidative stress and inflammatory tissue damage, this reference provides a comprehensive overview of cutting-edge research on the intracellular events mediating or preventing oxidative stress and pro-inflammatory processes induced by endogenous and xenobiotic factors-analyzing the implications of oxidative stress and inflammatory damage in the pathogenesis of human disorders such as cancer, neurodegenerative disease, and diabetes.

Spis treści

Oxidants and Antioxidants: Mechanism of Action and Regulation of Gene Expression by Bio?avonoids
Transcriptional Regulation of Cellular Antioxidant Defense Mechanisms
Redox Regulation of In?ammatory Tissue Damage by Thioredoxin
Regulation of NF-kB-Driven In?ammatory Genes by Phytoestrogens
Nuclear Factor-kB as Target for Chemoprevention
Heme Oxygenase-1: An Emerging Major Cellular Defense Against Cigarette Smoke-Induced Oxidative Stress and Cytotoxicity
Biphasic Induction of HO-1 in Macrophages Treated with Lipopolysaccharide: Role of HO-1 Induction in Cell Survival from Oxidative Stress
The Role of Ga12 Proteins in the PKC and JNK-Dependent Induction of NOS by Thrombin
Actions of 8-Hydroxyguanine in DNA
Role of Oxidative Stress in Hypercholesterolemia-Induced In?ammation
Oxidative Stress in Rheumatoid Arthritis
Roles of Carbon Monoxide and Nitric Oxide in Liver Damage
Role of Oxidative Stress and In?ammatory Response in Smokers and Chronic Obstructive Pulmonary Disease
Association of Chronic In?ammation with Carcinogenesis: Implications of Anti-In?ammatory Strategies for Cancer Prevention
Molecular In?ammation as an Underlying Mechanism of Aging: The Anti-in?ammatory Action of Calorie Restriction
Oxidative Stress in Mitochondria: The Involvement in Neurodegenerative Diseases
Implications of In?ammatory Stress in Alzheimer's Disease
Biomarkers for Evaluating Antioxidant Effects
Antioxidant and Neuroprotective Potentials
Resveratrol-A Unique Polyphenolic Antioxidant Present in Grape Skins and Red Wine-Is a Preventive Medicine Against a Variety of Degenerative Diseases
Molecular Mechanisms of Prevention Against Allergic Rhinitis by Aller-7, A Novel Polyherbal Formulation
Antioxidant Character of Selenium and Its Survival Signals by Activation of PI3-K/Akt Pathways
Neuroprotection by Rasagiline and Related Propargylamines Is Mediated by Suppression of Mitochondrial Death Signal and Induction of Antiapoptotic Genes
Index

O autorze

Young-Joon Surh