Nucleic Acids in Medicinal Chemistry and Chemical Biology: Drug Development and Clinical Applications

ISBN-13: 9781119692744 / Angielski / Twarda / 2023 / 600 str.

Jyoti Chattopadhyaya; Li-He Zhang; Xinjing Tang

Spis treści

Chapter 1. Phosph(on)ate Prodrugs-prof.Junbiao Chang.docxchapter 2-Cyclic Dinucleotides A New Generation Drug for Immune Therapy-prof Xi.docxChapter 3-Enzymatic and Endogenous Synthesis of NAD(P)-derived Calcium-mobilizing Messengers-Prof Lee.docxChapter 4-Selenium Atom-modified Nucleic Acids for Structural, Functional and Diagnostic Studies-prof huang.docxchapter 5-Sequence-specific chromosomal DNA binders an unfulfilled promise-Prof Sugiyama.docxchapter 6- DNA synthesis and synthetic genome-prof Yuan.docxChapter 7-Methods for mapping of nucleic acids epigenetic modifications and its clinic applications-prof zhou.docxChapter 8-main text.docxChapter 9-nucleic acid-based nanocarriers as drug delivry system-Prof. Jongbum Lee-no figure.docxChapter 10.docxChapter 11-Oligonucleotide therapeutics-Prof. Yang.docxChapter 12-CRISPRCas9 a therapeutic solution by manipulating nucleic acids-prof.Deng.docxchapter 13-Aptamer properties, functions and applications-prof Tan.docxchapter 14-G-quadruplex as a platform for new perspectives in nucleic acid targeting for therapeutic applications-Prof.Sissi.doc

O autorze

Lihe Zhang is President of the Academic Committee of State Key Laboratory of Natural & Biomimetic Drugs and Professor of Medicinal Chemistry at Peking University.Xinjing Tang is Professor of Medicinal Chemistry at Peking University.Zhen Xi is Chairman of the Department of Chemical Biology, Deputy Director of the State Key Laboratory of Element-Organic Chemistry, Professor of Pesticide Science and Chemical Biology, and Vice Dean for Academic Affairs of the College of Chemistry at Nankai University.Jyoti Chattopadhyaya is Chairman of the Department of Cell and Molecular Biology and Chair of Bioorganic Chemistry at the University of Uppsala.