Nucleic Acids and Molecular Biology

ISBN-13: 9783642465987 / Angielski / Miękka / 2012 / 243 str.

Spis treści

Drugs and Minor Groove Binding in B-DNA: Netropsin and Hoechst 33258.- The Molecular Structure of Base Pair Mismatches.- Interactions Between Antitumor Drugs and DNA.- Conformation of DNA Base Pair Mismatches in Solution.- Energetics of the B-Z DNA Transition.- Z-DNA: Exploring the Biological Significance.- The Extrusion of Cruciform Structures in Supercoiled DNA-Kinetics and Mechanisms.- DNA Curvature.- Fidelity of DNA Synthesis.- RecA Protein and Its Interaction with DNA.- Initiation of Prokaryotic Transcription — Kinetic and Structural Approaches.- Yeast DNA Topoisomerases and Their Structural Genes.- Antisense RNA.- Cell-Type Specificity of Transcription: The Immunoglobulin Heavy Chain Enhancer as a Model System.