Novel Optical Resolution Technologies

ISBN-13: 9783540463177 / Angielski / Twarda / 2007 / 313 str.

Kenichi Sakai;Noriaki Hirayama;Rui Tamura

Opis

Preferential Crystallization - Mechanism and Scope of Preferential Enrichment, a Symmetry Breaking Enantiomeric Resolution Phenomenon - Racemization, Optical Resolution, and Crystallization-induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates - Advantages of Structural Similarities of the Reactants in Optical Resolution Processes - Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition - New Resolution Technologies Controlled by Chiral Discrimination Mechanisms - Molecular Mechanisms of Dielectrically Controlled Resolution (DCR) - From Racemates to Single Enantiomers - Chiral Synthetic Drugs over the Recent 20 Years.

Spis treści

G. Coquerel: Preferential Crystallization.- R. Tamura, H. Takahashi, D. Fujimoto, T. Ushio: Mechanism and Scope of Preferential Enrichment, a Symmetry-Breaking Enantiomeric Resolution Phenomenon.- R. Yoshioka: Racemization, Optical Resolution, and Crystallization-Induced Asymmetric Transformation of Amino Acids and Pharmaceutical Intermediates.- F. Faigl, J. Schindler, E. Fogassy: Advantages of Structural Similarities of the Reactants in Optical Resolution Processes.- R.M. Kellogg , B. Kaptein, T.R. Vries: Dutch Resolution of Racemates and the Roles of Solid Solution Formation and Nucleation Inhibition.- K. Sakai, R. Sakurai, H. Nohira: New Resolution Technologies Controlled by Chiral Discrimination Mechanisms.- K. Sakai, R. Sakurai, N. Hirayama: Molecular Mechanisms of Dielectrically Controlled Resolution (DCR).- H. Murakami: From Racemates to Single Enantiomers – Chiral Synthetic Drugs over the Recent 20 Years