Hans Krebs: Volume 1: The Formation of a Scientific Life, 1900-1933

ISBN-13: 9780195070729 / Angielski / Twarda / 1991 / 512 str.

Frederic Lawrence Holmes

Opis

This is the first volume of a comprehensive scientific biography of Hans Krebs, one of the world's foremost biochemists. It treats his childhood, his medical education and scientific apprenticeship under Otto Warburg, his emergence as an independent investigator, and his discovery of the urea cycle in 1932. This early achievement, and his discovery of the citric acid cycle, are viewed as foundations for the modern structure of intermediary metabolism. During the writing of this fascinating history, the author had access to a complete set of Krebs' laboratory notebooks that reveal the daily dimensions of scientific creativity. Based in addition on many personal interviews with its subject, the Krebs biography is certain to interest and intrigue biochemists and historians of science alike. Volume 2: Hans Krebs: Architect of Intermediary Metabolism 1933-37, will appear in spring, 1993.

Recenzje

'This is not only a study of Krebs's research, it is also a comprehensive biography of Krebs's personal as well as scientific life ... These two volumes represent an extraordinary achievement, as a biography of a man, living in a time of turmoil and upheaval, who emerged as a great scientists. The story of both the man and the science is full and rewarding. Among studies of biochemists, I know of nothing in the least comparable with Holmes's achievement here, in its depth and breadth.' John T. Edsall, Harvard University, Nature, Vol. 366, December 1993

Spis treści

Intermediary metabolism in the first third of the twentieth century; Boyhood in Hildesheim; Outward movement; Clinical years; The research apprentice; Initiative and dependence; Moves toward autonomy; Freiburg: The foundation of a career; The ornithine effect; The formation of urea; The rewards of success; The brief life of a Freiburg school of metabolism; Reflections on the formation of a scientific life.