Experimental Glycoscience: Glycobiology

ISBN-13: 9784431779216 / Angielski / Miękka / 2008 / 498 str.

Naoyuki Taniguchi; Akemi Suzuki; Yukishige Ito

Opis

The aim of this book is to provide experimental protocols covering many aspects of glycobiology, glycotechnology, and chemistry: biochemistry, molecular and cellular biology, genetics, physiology, and medicine. The protocols are all self-contained descriptions of the equipment and reagents needed, followed by details of the experimental procedure. In the post-genomic era, glycobiology is coming of age because more than half of proteins are glycosylated and the importance of sugar chains in various fields of life science research cannot be disregarded. Many scientists had not entered this area because glycobiology and glycoscience used to be considered difficult fields. This book, therefore, is presented much like a cookbook which can help scientists in fields other than glycobiology and glycoscience carry out research more easily.

Recenzje

From the reviews:

"The book is a useful manual for many researchers in the field of glycobiology, biochemistry, and biotechnology. This book can be a very useful tool for teachers and students of colleges and universities." (G. Ya. Wiederschain, Biochemistry, Vol. 74 (6), 2009)

Spis treści

1. Glycosyltransferase Genes

  Part 1. Glycosyltransferases
  Part 2. Sugar-Modified Enzymes
  Part 3. Transporters
  Part 4. Glycosidases 
  Part 5. Animal Lectins

2. Functional Analyses of Sugar Chains

  Part 6. Immunology
  Part 7. Brains and Nerves
  Part 8. Quality Control of Proteins
  Part 9. Golgi and Lysosomal Diseases
  Part 10. Infections
  Part 11. Cancer
  Part 12. Regeneration Medicine and Transplantation
  Part 13. Fertilization
  Part 14. Development, Differentiation, and Morphogenesis
  Part 15. Muscle Dystrophy and Carbohydrate Disorders of Glycosylation
  Part 16. Lifestyle-Related Diseases
  Part 17. IgA Nephropathy
  Part 18. Growth Factor Receptors
  Part 19. Blood Groups and Blood Cells

3. Glycosyltransferase Gene KO Mice

  Part 20. Glycosyltransferase Gene KO Mice

4. Infrastructures and Research Resources

  Part 21. Glycosyltransferases and Related Genes, and Useful Cell Lines
  Part 22. Sugar Library
  Part 23. Database
  Part 24. Microarray

O autorze

Naoyuki Taniguchi graduated from the Hokkaido University School of Medicine, followed by an M.D. degree in 1967, and completed the doctoral course of medicine at the Graduate School of Hokkaido University and obtained a Ph.D in 1972. He was then appointed assistant professor at the Hokkaido University School of Medicine in 1975 and was a visiting professor in the group of Dr. Alton Meister at Cornell University Medical College between 1976 and 1977. Returning to Hokkaido University, he joined the Biochemistry Laboratory at the Cancer Institute, before being appointed as a full professor at the Department of Biochemistry, Osaka University Medical School in 1986. Professor Taniguchi is an honorary member of the American Society for Biochemistry and Molecular Biology and has received numerous awards, among them the International Glycoconjugate Organization (IGO) Award in 2001.