Synthesis and Biological Evaluation of Cu, Ni, Mn and Zn Complexes

ISBN-13: 9783659623639 / Angielski / Miękka / 2014 / 60 str.

Ehsan Tayyeba;Bukhari Iftikhar Hussain;Ilyas Sadia

Opis

New Schiff base complexes of Copper, Nickel, Manganese and Zinc derived from Azithromycin with salicylaldehyde have been synthesized. Complexes was synthesized and physico-chemically characterized by solubility testing, melting point and FTIR. The synthesized metal complex was evaluated for antibacterial activity against the multidrug resistant pathogens, such as Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus and antifungal activity in opposition to Aspergillus niger and Aspergillus flavus. The metal complex showed the significant antibacterial and antifungal activity in comparison with free ligand.

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O autorze

Miss Tayyaba Ehsan has completed her M.Phil from Govt. Collage University, Faisalabad,Pakistan.Her area of specialization is Inorganic Chemistry. She is member of Chemical Society of Pakistan.