Name Reactions for Carbocyclic Ring Formations

ISBN-13: 9780470085066 / Angielski / Twarda / 2010 / 772 str.

Jie Jack Li; E. J. Corey

Opis

Ring formations are an important tool in the synthetic arsenal of organic chemistry. Name Reactions on Carbocyclic Ring Formations continues the authoritative series on name reactions in organic chemistry by comprehensively covering name reactions specific to ring formation.

Recenzje

"This comprehensive reference guide offers information on the most current developments in name reactions on carbocyclic ring formations, and is intended as a resource for both students and professionals working in organic chemistry and polymer synthesis." (Booknews, 1 February 2011)

Spis treści

Foreword.

Preface.

Contributing Authors.

Chapter 1 Three–Membered Carbocycles.

1.1 Freund Reaction.

1.2 Kishner Cyclopropane Synthesis.

1.3 Kulinovich Cyclopropanol Synthesis.

1.4 Simmons–Smith Reaction.

Chapter 2 Four–Membered Carbocycles.

2.1 Staudinger Ketene Cycloaddition.

Chapter 3 Five–Membered Carbocycles.

3.1 Danheiser Annulation.

3.2 Dieckmann Condensation.

3.3 Favorskii Rearrangement.

3.4 Nazarov Cyclization.

3.5 Pauson–Khand Reaction.

3.6 Weiss Cook Reaction.

Chapter 4 Six–Membered Carbocycles.

4.1 Bardhan–Sengupta Pheantherene Synthesis.

4.2 Bergman Cyclization.

4.3 Bogert–Cook Reaction.

4.4 Bradsher Cycloaddition and Bradsher Reaction.

4.5 Bradsher Reaction.

4.6 Darzens Synthesis of Tetralin Derivatives.

4.7 Diels–Alder Reaction.

4.8 Dötz Benzannulation.

4.9 Elbs Reaction.

4.10 Fujimoto–Belleau Reaction.

4.11 Haworth Reaction.

4.12 Moore Cyclization.

4.13 Myers–Saito Cyclization.

4.14 Robinson Annulation.

4.15 Scholl Reaction.

Chapter 5 Large–Ring Carbocycles.

5.1 Buchner Reaction.

5.2 de Mayo Reaction.

5.3 Ring–closing Metathesis (RCM).

5.4 Thorpe–Ziegler Reaction.

Chapter 6 Transformations of Carbocycles.

6.1 Blanc Chloromethylation Reaction.

6.2 Asymmetric Friedel–Crafts Reactions: Past to Present.

6.3 Houben–Hoesch Reaction.

6.4 Kolbe–Schmitt Reaction.

6.5 Vilsmeier–Haack Reaction.

6.6 von Richter Reaction.

Appendices.

1 Contents Volume 1: Name Reactions in Heterocyclic Chemistry.

2 Contents Volume 2: Name Reactions for Functional Group Transformations.

3 Contents Volume 3: Name Reactions for Homologations Part I.

4 Contents Volume 4: Name Reactions for Homologations Part II.

5 Contents Volume 6: Name Reactions in Heterocyclic Chemistry Part II.

Subject Index.

O autorze

JIE JACK LI is a chemist at Bristol–Myers Squibb Company in Wallingford, Connecticut. He has authored or edited various books, including Name Reactions in Heterocyclic Chemistry, Name Reactions for Functional Group Transformations, Name Reactions for Homologations, Parts I and II, Contemporary Drug Synthesis, The Art of Drug Synthesis, and Modern Drug Synthesis, all published by Wiley.

Blurb

A valuable additon to the literature by any measure and surely will prove its merit in years to come. The new knowledge that arises with its help will be impressive and of great benefit to humankind.
From the Foreword by E.J. Corey, Nobel laureate

An invaluable guide to name reactions on carbocyclic ring formations

Ring–forming reactions have found widespread applicability advantageous to the interests of science. Currently, they are used in all areas of organic synthesis, including medicinal and pharmaceutical, agricultural, fine chemicals, and, most recently, polymer science.

This all–inclusive reference focuses on name reactions specific to ring formations, and details the carbocyclic characteristics that make these rings an effective tool in the synthetic arsenal of organic chemistry with:

• A description of a ring–forming reaction included in each section highlighting the following: historical perspective, a mechanism for the reaction, variations and improvements on the reaction, synthetic utilities of the reaction, experimental details, and current references

• Coverage of fundamental topics, including various carbocycles (three, five, six, and large–ring carbocycles) and the transformation of carbocycles

• Examples of common name reactions, such as Simmons–Smith, Pauson–Khand, Danheiser annulation, Diels–Alder, Robinson annulation, Stork enamine reaction, and ring–closing metathesis

An excellent resource for both students and professionals involved with organic chemistry and polymer synthesis, Name Reactions for Carbocyclic Ring Formations delivers essential information on the latest developments from leading experts in the field and serves as a springboard to further advance scientific discovery.