Kategoria BISAC: Science >> Bioinformatics

Bioinformatics can be loosely defined as the collection, classification, storage, and analysis of biochemical and biological information using computers and mathematical algorithms. Although no single person or group started the field wholly on their own, Temple Smith, Ph.D., a professor at Boston University, is generally credited with coining the term. Bioinformatics represents a marriage of biology, medicine, computer science, physics, and mathematics, fields of study that have historically existed as mutually exclusive disciplines.

Concurrently,...

This volume discusses the latest developments in clinical proteomics and describes in detail the algorithms used in publicly available software tools. It should be considered as a proteomics-bioinformatics resource and offers the opportunity to understand the details of the various publicly available algorithms. The book should not only be considered as a pure bioinformatics resource filled with complex equations but it aims to describe the background of the biology and experimental methods. However, detailed experimental protocols will only be referenced. The pro and cons of the various...

This book constitutes the refereed proceedings of the Third International Conference on Theory and Applications of Models of Computation, TAMC 2006, held in Beijing, China, in May 2006. The 75 revised full papers presented together with 7 plenary talks were carefully reviewed and selected from 319 submissions. All major areas in computer science, mathematics (especially logic) and the physical sciences particularly with regard to computation and computability theory are addressed.

This, the 4th Transactions on Computational Systems Biology volume, contains carefully selected and enhanced contributions presented at the first Converging Science conference held at the University of Trento, Italy, in December 2004.

Dedicated especially to models and metaphors from biology to bioinformatics tools, the 11 papers selected for the special issue cover a wide range of bioinformatics research, such as foundations of global computing, interdisciplinarity in innovation initiatives, biodiversity, and more.

Recent advances in understanding the thermodynamics of macromolecules, the topological properties of gene networks, the organization and mutation capabilities of genomes, and the structure of populations make it possible to incorporate these key elements into a broader and deeply interdisciplinary view of molecular evolution. This book gives an account of such a new approach, through clear tutorial contributions by leading scientists.

This volume, the 7th in the Transactions on Computational Systems Biology series, contains a fully refereed and carefully selected set of papers from two workshops: BioConcur 2004 held in London, UK in August 2004 and BioConcur 2005 held in San Francisco, CA, USA in August 2005.

The 8 papers chosen for this special issue are devoted to various aspects of computational methods, algorithms, and techniques in bioinformatics.

This book presents applications of bioinformatics tools that experimental research scientists use in "daily practice." Its interdisciplinary approach combines computational and experimental methods to solve scientific problems. The book begins with reviews of computational methods for protein sequence-structure-function analysis, followed by methods that use experimental data obtained in the laboratory to improve functional predictions.

Systems biology is defined for the purpose of this study as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. This involves a variety of approaches, such as the identification and validation of networks, the creation of appropriate datasets, the development of tools for data acquisition and software development, and the use of modeling and simulation software in close linkage with experiment. All of these are discussed in this volume. Of course, the definition...

Bioinformatics has ignited the imagination of scientists, entrepreneurs and the general public. At the meeting place of two fast growth disciplines, biology and computer science Bioinformatics is one of the cornerstones of the new biology. It is clearly pivotal to the translation of high throughput projects such the human genome project into useful knowledge. Yet despite all this attention, there is no consensus on what exactly is Bioinformatics. There are several canonical topics, such as gene structure prediction, protein functional classification or structure prediction. The present...

Plant nutrition in greenhouse cultivation differs in many essential aspects from field crops and justified the development of a special publication on this subject. The high productions realised and the specific produce quality requirements ensure high uptakes of nutrients and a careful tuning of the application. The covering with glass or plastic is responsible for specific climatic conditions, which in modern greenhouse can be fully adjusted to the requirements of the crop by automatic climate control. The natural precipitation is excluded, thus, the water has to be applied in...

Quantitative trait locus (QTL) mapping is used to discover the genetic and molecular architecture underlying complex quantitative traits. It has important applications in agricultural, evolutionary, and biomedical research. R/qtl is an extensible, interactive environment for QTL mapping in experimental crosses. It is implemented as a package for the widely used open source statistical software R and contains a diverse array of QTL mapping methods, diagnostic tools for ensuring high-quality data, and facilities for the fit and exploration of multiple-QTL models, including QTL x QTL and QTL...

This book defines the field of systems biology, one of the newest and fastest developing fields in science today. It discusses the most effective experimental and computational strategies and highlights new and emerging applications. Cell biologists and other readers will discover many benefits for industry, such as the new network-based drug-target design validation. The authors also thoroughly explore testing.