Kategoria BISAC: Science >> Bioinformatics

Now is a critical time in pediatric informatics. As information technologies electronic health records (EHRs), personal health records (PHRs), computerized physician order entry (CPOE) and standards (HL7) are developed to improve the quality of health care, it is imperative for policy makers and pediatricians to be aware of their impact on pediatric care and child health. Informed child advocates must be at the planning table as national and regional health information networks are developed to insure the unique health care needs of children are being met.

Pediatric Informatics:...

This book features the refereed proceedings of the 2nd International Symposium on Computer Science in Russia held in September 2007. The 35 papers cover theory track deals with algorithms, protocols, and data structures; complexity and cryptography; formal languages, automata and their applications to computer science; computational models and concepts; proof theory; and applications of logic to computer science. Many applications are presented.

Here is a work that adds much to the sum of our knowledge in a key area of science today. It is concerned with the estimation of discrete-time semi-Markov and hidden semi-Markov processes. A unique feature of the book is the use of discrete time, especially useful in some specific applications where the time scale is intrinsically discrete. The models presented in the book are specifically adapted to reliability studies and DNA analysis. The book is mainly intended for applied probabilists and statisticians interested in semi-Markov chains theory, reliability and DNA analysis, and for...

Every biological system is the outcome of its evolution; therefore, the deciphering of its evolutionary history is of tremendous importance to understand the biology of a system.

Since 1997 scientists of different disciplines have held an annual "Evolutionary Biology Meeting" at Marseille (France) in order to discuss their research developments, exchange ideas and start collaborations. Consisting of the most representative talks of the 11th meeting, this book provides an up-to-date overview of evolutionary concepts and how these concepts can be applied to a better...

This book constitutes the refereed proceedings of the 5th International Conference on Theory and Applications of Models of Computation, TAMC 2008, held in Xi'an, China in April 2008.

The 48 revised full papers presented together with 2 invited talks and 1 plenary lecture were carefully reviewed and selected from 192 submissions. The papers address current issues of all major areas in computer science, mathematics (especially logic) and the physical sciences - computation, algorithms, complexity and computability theory in particular. With this crossdisciplinary character the conference...

An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry.

Included is an overview of bioinformatics, the full spectrum of genome annotation approaches including; genome analysis and gene prediction, gene regulation analysis and expression, genome variation and QTL analysis, large scale...

Biomolecular sequence comparison is the origin of bioinformatics. This book gives a complete in-depth treatment of the study of sequence comparison.

A comprehensive introduction is followed by a focus on alignment algorithms and techniques, proceeded by a discussion of the theory. The book examines alignment methods and techniques, features a new issue of sequence comparison - the spaced seed technique, addresses several new flexible strategies for coping with various scoring schemes, and covers the theory on the significance of high-scoring segment pairs between two unalignment...

Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and classification problems in two main high-throughput platforms: microarray gene expression and phylogenic analysis.

The book explores Bayesian techniques and models for detecting differentially expressed genes,...

Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called "conductance injection") allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer.

The technique can be implemented from neural simulation environments and a variety of custom-made or commercial systems. The real-time interaction between the computer and cell also enables the design of recording paradigms with unprecedented accuracy via a...